Q9BW84 (Q9BW84_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Transporter RuleBase RU003732

Gene names

Name:

SLC6A2 EMBL AAH00563.2

Organism

Homo sapiens (Human) EMBL AAH00563.2

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	325 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the sodium:neurotransmitter symporter (SNF) family. RuleBase RU003732

Ontologies

Keywords
Biological process	Symport RuleBase RU003732 SAAS SAAS000175 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000175
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	neurotransmitter:sodium symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH00563.2

Sequences

	Sequence		Length	Mass (Da)
	Q9BW84 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: C3468A7752ED3479	FASTA	325	36,513
	10 20 30 40 50 60 LYFSLWKGVK TSGKVWIDAA TQIFFSLGAG FGVLIAFASY NKFDNNCYRD ALLTSSINCI 70 80 90 100 110 120 TSFVSGFAIF SILGYMAHEH KVNIEDVATE GAGLVFILYP EAISTLSGST FWAVVFFVML 130 140 150 160 170 180 LALGLDSSMG GMEAVITGLA DDFQVLKRHR KLFTFGVTFS TFLLALFCIT KGGIYVLTLL 190 200 210 220 230 240 DTFAAGTSIL FAVLMEAIGV SWFYGVDRFS NDIQQMMGFR PGLYWRLCWK FVSPAFLLFV 250 260 270 280 290 300 VVVSIINFKP LTYDDYIFPP WANWVGWGIA LSSMVLVPIY VIYKFLSTQG SLWERLAYGI 310 320 TPENEHHLVA QRDIRQFQLQ HWLAI

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAH00563.2.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC000563 mRNA. Translation: AAH00563.2.
IPI	IPI00642795.
UniGene	Hs.78036.
3D structure databases
ProteinModelPortal	Q9BW84.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9BW84.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG071421.
Gene expression databases
ArrayExpress	Q9BW84.
Bgee	Q9BW84.
Family and domain databases
InterPro	IPR000175. Na/ntran_symport. [Graphical view]
PANTHER	PTHR11616. PTHR11616. 1 hit.
Pfam	PF00209. SNF. 1 hit. [Graphical view]
PRINTS	PR00176. NANEUSMPORT.
PROSITE	PS50267. NA_NEUROTRAN_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9BW84_HUMAN

Accession

Primary (citable) accession number: Q9BW84

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	March 1, 2004
Last modified:	October 3, 2012
This is version 65 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.