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Protein

Uncharacterized membrane protein C19orf24

Gene

C19orf24

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000118050-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein C19orf24
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:26073. C19orf24.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • cytoplasm Source: HGNC
  • extracellular region Source: BHF-UCL
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000228300.
PharmGKBiPA134930220.

Polymorphism and mutation databases

DMDMi294862428.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000007938527 – 132Uncharacterized membrane protein C19orf24Add BLAST106

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi47N-linked (GlcNAc...)Sequence analysis1
Modified residuei113PhosphothreonineCombined sources1
Modified residuei117PhosphoserineCombined sources1
Modified residuei120PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ9BVV8.
PaxDbiQ9BVV8.
PeptideAtlasiQ9BVV8.
PRIDEiQ9BVV8.

PTM databases

iPTMnetiQ9BVV8.
PhosphoSitePlusiQ9BVV8.

Expressioni

Gene expression databases

BgeeiENSG00000228300.
CleanExiHS_C19orf24.
ExpressionAtlasiQ9BVV8. baseline and differential.
GenevisibleiQ9BVV8. HS.

Organism-specific databases

HPAiHPA043279.

Interactioni

Protein-protein interaction databases

IntActiQ9BVV8. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ9BVV8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J2R5. Eukaryota.
ENOG41129NG. LUCA.
GeneTreeiENSGT00530000064649.
HOGENOMiHOG000111985.
InParanoidiQ9BVV8.
OMAiQPGAPHN.
PhylomeDBiQ9BVV8.
TreeFamiTF339572.

Family and domain databases

InterProiIPR009565. DUF1180.
[Graphical view]
PfamiPF06679. DUF1180. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BVV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPRVLQPPL LLLLLALLLA ALPCGAEEAS PLRPAQVTLS PPPAVTNGSQ
60 70 80 90 100
PGAPHNSTHT RPPGASGSAL TRSFYVILGF CGLTALYFLI RAFRLKKPQR
110 120 130
RRYGLLANTE DPTEMASLDS DEETVFESRN LR
Length:132
Mass (Da):14,249
Last modified:April 20, 2010 - v2
Checksum:i58C95478850F1818
GO

Sequence cautioni

The sequence BAA91305 differs from that shown.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004258 Genomic DNA. No translation available.
BC000890 mRNA. Translation: AAH00890.2.
AK000647 mRNA. Translation: BAA91305.1. Sequence problems.
CCDSiCCDS12060.2.
RefSeqiNP_060384.3. NM_017914.3.
UniGeneiHs.591383.

Genome annotation databases

EnsembliENST00000409293; ENSP00000386557; ENSG00000228300.
GeneIDi55009.
KEGGihsa:55009.
UCSCiuc002lrw.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004258 Genomic DNA. No translation available.
BC000890 mRNA. Translation: AAH00890.2.
AK000647 mRNA. Translation: BAA91305.1. Sequence problems.
CCDSiCCDS12060.2.
RefSeqiNP_060384.3. NM_017914.3.
UniGeneiHs.591383.

3D structure databases

ProteinModelPortaliQ9BVV8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9BVV8. 1 interactor.

PTM databases

iPTMnetiQ9BVV8.
PhosphoSitePlusiQ9BVV8.

Polymorphism and mutation databases

DMDMi294862428.

Proteomic databases

MaxQBiQ9BVV8.
PaxDbiQ9BVV8.
PeptideAtlasiQ9BVV8.
PRIDEiQ9BVV8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409293; ENSP00000386557; ENSG00000228300.
GeneIDi55009.
KEGGihsa:55009.
UCSCiuc002lrw.5. human.

Organism-specific databases

CTDi55009.
GeneCardsiC19orf24.
HGNCiHGNC:26073. C19orf24.
HPAiHPA043279.
neXtProtiNX_Q9BVV8.
OpenTargetsiENSG00000228300.
PharmGKBiPA134930220.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J2R5. Eukaryota.
ENOG41129NG. LUCA.
GeneTreeiENSGT00530000064649.
HOGENOMiHOG000111985.
InParanoidiQ9BVV8.
OMAiQPGAPHN.
PhylomeDBiQ9BVV8.
TreeFamiTF339572.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000118050-MONOMER.

Miscellaneous databases

GenomeRNAii55009.
PROiQ9BVV8.

Gene expression databases

BgeeiENSG00000228300.
CleanExiHS_C19orf24.
ExpressionAtlasiQ9BVV8. baseline and differential.
GenevisibleiQ9BVV8. HS.

Family and domain databases

InterProiIPR009565. DUF1180.
[Graphical view]
PfamiPF06679. DUF1180. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCS024_HUMAN
AccessioniPrimary (citable) accession number: Q9BVV8
Secondary accession number(s): Q9NWS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: April 20, 2010
Last modified: November 2, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.