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Protein

Fibronectin type III domain-containing protein 11

Gene

FNDC11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Fibronectin type III domain-containing protein 11
Gene namesi
Name:FNDC11
Synonyms:C20orf195
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:28764. FNDC11.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: UniProtKB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000125531.
PharmGKBiPA142672215.

Polymorphism and mutation databases

BioMutaiC20orf195.
DMDMi74761293.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002328671 – 318Fibronectin type III domain-containing protein 11Add BLAST318

Proteomic databases

PaxDbiQ9BVV2.
PeptideAtlasiQ9BVV2.
PRIDEiQ9BVV2.

PTM databases

iPTMnetiQ9BVV2.
PhosphoSitePlusiQ9BVV2.

Expressioni

Gene expression databases

BgeeiENSG00000125531.
CleanExiHS_C20orf195.
ExpressionAtlasiQ9BVV2. baseline and differential.
GenevisibleiQ9BVV2. HS.

Organism-specific databases

HPAiHPA041341.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi122493. 25 interactors.
IntActiQ9BVV2. 39 interactors.
MINTiMINT-1444108.

Structurei

3D structure databases

ProteinModelPortaliQ9BVV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini210 – 307Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST98

Phylogenomic databases

eggNOGiENOG410IGYC. Eukaryota.
ENOG410YC0Q. LUCA.
GeneTreeiENSGT00390000006008.
HOGENOMiHOG000231855.
HOVERGENiHBG080464.
InParanoidiQ9BVV2.
OMAiNTMFQLI.
OrthoDBiEOG091G0D2Y.
PhylomeDBiQ9BVV2.
TreeFamiTF338188.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9BVV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTHVAGLGL DKMKLGNPQS FLDQEEADDQ QLLEPEAWKT YTERRNALRE
60 70 80 90 100
FLTSDLSPHL LKRHHARMQL LRKCSYYIEV LPKHLALGDQ NPLVLPSALF
110 120 130 140 150
QLIDPWKFQR MKKVGTAQTK IQLLLLGDLL EQLDHGRAEL DALLRSPDPR
160 170 180 190 200
PFLADWALVE RRLADVSAVM DSFLTMMVPG RLHVKHRLVS DVSATKIPHI
210 220 230 240 250
WLMLSTKMPV VFDRKASAAH QDWARLRWFV TIQPATSEQY ELRFRLLDPR
260 270 280 290 300
TQQECAQCGV IPVAACTFDV RNLLPNRSYK FTIKRAETST LVYEPWRDSL
310
TLHTKPEPLE GPALSHSV
Length:318
Mass (Da):36,526
Last modified:June 1, 2001 - v1
Checksum:i9FDA08CB588A9699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121829 Genomic DNA. No translation available.
BC000912 mRNA. Translation: AAH00912.1.
CCDSiCCDS13526.1.
RefSeqiNP_001306081.1. NM_001319152.1.
NP_001306082.1. NM_001319153.1.
NP_076964.1. NM_024059.3.
XP_011527343.1. XM_011529041.2.
UniGeneiHs.197755.

Genome annotation databases

EnsembliENST00000370097; ENSP00000359115; ENSG00000125531.
ENST00000370098; ENSP00000359116; ENSG00000125531.
ENST00000615526; ENSP00000480914; ENSG00000125531.
GeneIDi79025.
KEGGihsa:79025.
UCSCiuc002yfj.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121829 Genomic DNA. No translation available.
BC000912 mRNA. Translation: AAH00912.1.
CCDSiCCDS13526.1.
RefSeqiNP_001306081.1. NM_001319152.1.
NP_001306082.1. NM_001319153.1.
NP_076964.1. NM_024059.3.
XP_011527343.1. XM_011529041.2.
UniGeneiHs.197755.

3D structure databases

ProteinModelPortaliQ9BVV2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122493. 25 interactors.
IntActiQ9BVV2. 39 interactors.
MINTiMINT-1444108.

PTM databases

iPTMnetiQ9BVV2.
PhosphoSitePlusiQ9BVV2.

Polymorphism and mutation databases

BioMutaiC20orf195.
DMDMi74761293.

Proteomic databases

PaxDbiQ9BVV2.
PeptideAtlasiQ9BVV2.
PRIDEiQ9BVV2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370097; ENSP00000359115; ENSG00000125531.
ENST00000370098; ENSP00000359116; ENSG00000125531.
ENST00000615526; ENSP00000480914; ENSG00000125531.
GeneIDi79025.
KEGGihsa:79025.
UCSCiuc002yfj.4. human.

Organism-specific databases

CTDi79025.
GeneCardsiFNDC11.
HGNCiHGNC:28764. FNDC11.
HPAiHPA041341.
neXtProtiNX_Q9BVV2.
OpenTargetsiENSG00000125531.
PharmGKBiPA142672215.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGYC. Eukaryota.
ENOG410YC0Q. LUCA.
GeneTreeiENSGT00390000006008.
HOGENOMiHOG000231855.
HOVERGENiHBG080464.
InParanoidiQ9BVV2.
OMAiNTMFQLI.
OrthoDBiEOG091G0D2Y.
PhylomeDBiQ9BVV2.
TreeFamiTF338188.

Miscellaneous databases

GenomeRNAii79025.
PROiPR:Q9BVV2.

Gene expression databases

BgeeiENSG00000125531.
CleanExiHS_C20orf195.
ExpressionAtlasiQ9BVV2. baseline and differential.
GenevisibleiQ9BVV2. HS.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFND11_HUMAN
AccessioniPrimary (citable) accession number: Q9BVV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: June 1, 2001
Last modified: April 12, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.