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Protein

Uncharacterized protein C20orf195

Gene

C20orf195

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C20orf195
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:28764. C20orf195.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672215.

Polymorphism and mutation databases

BioMutaiC20orf195.
DMDMi74761293.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Uncharacterized protein C20orf195PRO_0000232867Add
BLAST

Proteomic databases

PaxDbiQ9BVV2.
PRIDEiQ9BVV2.

PTM databases

iPTMnetiQ9BVV2.
PhosphoSiteiQ9BVV2.

Expressioni

Gene expression databases

BgeeiQ9BVV2.
CleanExiHS_C20orf195.
ExpressionAtlasiQ9BVV2. baseline and differential.
GenevisibleiQ9BVV2. HS.

Organism-specific databases

HPAiHPA041341.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CALCOCO2Q131374EBI-744935,EBI-739580
CCDC102BA1A4H13EBI-744935,EBI-10171570
CDAP323203EBI-744935,EBI-9250559
FAM9BQ8IZU03EBI-744935,EBI-10175124
GOLGA2Q083793EBI-744935,EBI-618309
GPBP1Q86WP23EBI-744935,EBI-2349758
GPBP1Q86WP2-43EBI-744935,EBI-10300058
HMBOX1Q6NT763EBI-744935,EBI-2549423
KRT40Q6A1623EBI-744935,EBI-10171697
LZTS2Q9BRK43EBI-744935,EBI-741037
MAGEA12Q6FHH83EBI-744935,EBI-10178394
MDFIQ997503EBI-744935,EBI-724076
MTUS2Q5JR593EBI-744935,EBI-742948
RBPMSQ930623EBI-744935,EBI-740322
RELQ048643EBI-744935,EBI-307352
SSX2IPQ9Y2D83EBI-744935,EBI-2212028
TRIM27P143733EBI-744935,EBI-719493

Protein-protein interaction databases

BioGridi122493. 25 interactions.
IntActiQ9BVV2. 20 interactions.
MINTiMINT-1444108.

Structurei

3D structure databases

ProteinModelPortaliQ9BVV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini210 – 30798Fibronectin type-IIIPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 fibronectin type-III domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IGYC. Eukaryota.
ENOG410YC0Q. LUCA.
GeneTreeiENSGT00390000006008.
HOGENOMiHOG000231855.
HOVERGENiHBG080464.
InParanoidiQ9BVV2.
OMAiNTMFQLI.
OrthoDBiEOG7MKW6N.
PhylomeDBiQ9BVV2.
TreeFamiTF338188.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BVV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTHVAGLGL DKMKLGNPQS FLDQEEADDQ QLLEPEAWKT YTERRNALRE
60 70 80 90 100
FLTSDLSPHL LKRHHARMQL LRKCSYYIEV LPKHLALGDQ NPLVLPSALF
110 120 130 140 150
QLIDPWKFQR MKKVGTAQTK IQLLLLGDLL EQLDHGRAEL DALLRSPDPR
160 170 180 190 200
PFLADWALVE RRLADVSAVM DSFLTMMVPG RLHVKHRLVS DVSATKIPHI
210 220 230 240 250
WLMLSTKMPV VFDRKASAAH QDWARLRWFV TIQPATSEQY ELRFRLLDPR
260 270 280 290 300
TQQECAQCGV IPVAACTFDV RNLLPNRSYK FTIKRAETST LVYEPWRDSL
310
TLHTKPEPLE GPALSHSV
Length:318
Mass (Da):36,526
Last modified:June 1, 2001 - v1
Checksum:i9FDA08CB588A9699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121829 Genomic DNA. Translation: CAI95748.1.
BC000912 mRNA. Translation: AAH00912.1.
CCDSiCCDS13526.1.
RefSeqiNP_001306081.1. NM_001319152.1.
NP_001306082.1. NM_001319153.1.
NP_076964.1. NM_024059.3.
XP_011527339.1. XM_011529037.1.
XP_011527343.1. XM_011529041.1.
UniGeneiHs.197755.

Genome annotation databases

EnsembliENST00000370097; ENSP00000359115; ENSG00000125531.
ENST00000370098; ENSP00000359116; ENSG00000125531.
ENST00000615526; ENSP00000480914; ENSG00000125531.
GeneIDi79025.
KEGGihsa:79025.
UCSCiuc002yfj.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121829 Genomic DNA. Translation: CAI95748.1.
BC000912 mRNA. Translation: AAH00912.1.
CCDSiCCDS13526.1.
RefSeqiNP_001306081.1. NM_001319152.1.
NP_001306082.1. NM_001319153.1.
NP_076964.1. NM_024059.3.
XP_011527339.1. XM_011529037.1.
XP_011527343.1. XM_011529041.1.
UniGeneiHs.197755.

3D structure databases

ProteinModelPortaliQ9BVV2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122493. 25 interactions.
IntActiQ9BVV2. 20 interactions.
MINTiMINT-1444108.

PTM databases

iPTMnetiQ9BVV2.
PhosphoSiteiQ9BVV2.

Polymorphism and mutation databases

BioMutaiC20orf195.
DMDMi74761293.

Proteomic databases

PaxDbiQ9BVV2.
PRIDEiQ9BVV2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370097; ENSP00000359115; ENSG00000125531.
ENST00000370098; ENSP00000359116; ENSG00000125531.
ENST00000615526; ENSP00000480914; ENSG00000125531.
GeneIDi79025.
KEGGihsa:79025.
UCSCiuc002yfj.4. human.

Organism-specific databases

CTDi79025.
GeneCardsiC20orf195.
HGNCiHGNC:28764. C20orf195.
HPAiHPA041341.
neXtProtiNX_Q9BVV2.
PharmGKBiPA142672215.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGYC. Eukaryota.
ENOG410YC0Q. LUCA.
GeneTreeiENSGT00390000006008.
HOGENOMiHOG000231855.
HOVERGENiHBG080464.
InParanoidiQ9BVV2.
OMAiNTMFQLI.
OrthoDBiEOG7MKW6N.
PhylomeDBiQ9BVV2.
TreeFamiTF338188.

Miscellaneous databases

GenomeRNAii79025.
PROiQ9BVV2.

Gene expression databases

BgeeiQ9BVV2.
CleanExiHS_C20orf195.
ExpressionAtlasiQ9BVV2. baseline and differential.
GenevisibleiQ9BVV2. HS.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Cervix.

Entry informationi

Entry nameiCT195_HUMAN
AccessioniPrimary (citable) accession number: Q9BVV2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.