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Protein

Protein PBDC1

Gene

PBDC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PBDC1
Alternative name(s):
Polysaccharide biosynthesis domain-containing protein 1
Gene namesi
Name:PBDC1
Synonyms:CXorf26
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:28790. PBDC1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA128394657.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 233233Protein PBDC1PRO_0000254105Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei126 – 1261Phosphoserine1 Publication
Modified residuei181 – 1811Phosphoserine1 Publication
Modified residuei197 – 1971Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9BVG4.
PaxDbiQ9BVG4.
PeptideAtlasiQ9BVG4.
PRIDEiQ9BVG4.

PTM databases

PhosphoSiteiQ9BVG4.

Expressioni

Gene expression databases

BgeeiQ9BVG4.
CleanExiHS_CXorf26.
ExpressionAtlasiQ9BVG4. baseline and differential.
GenevestigatoriQ9BVG4.

Organism-specific databases

HPAiHPA003155.

Interactioni

Protein-protein interaction databases

BioGridi119416. 14 interactions.
IntActiQ9BVG4. 6 interactions.
STRINGi9606.ENSP00000362456.

Structurei

3D structure databases

ProteinModelPortaliQ9BVG4.
SMRiQ9BVG4. Positions 26-155.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PBDC1 family.Curated

Phylogenomic databases

eggNOGiNOG285457.
GeneTreeiENSGT00390000016333.
HOGENOMiHOG000189636.
HOVERGENiHBG059712.
InParanoidiQ9BVG4.
OMAiLRLNCSQ.
PhylomeDBiQ9BVG4.
TreeFamiTF314442.

Family and domain databases

Gene3Di1.10.3560.10. 1 hit.
InterProiIPR021148. Put_polysacc_synth.
IPR008476. UPF0368_met/fun.
IPR023139. Yst0336-like_domain.
[Graphical view]
PANTHERiPTHR13410. PTHR13410. 1 hit.
PfamiPF04669. Polysacc_synt_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BVG4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAATSGTDEP VSGELVSVAH ALSLPAESYG NDPDIEMAWA MRAMQHAEVY
60 70 80 90 100
YKLISSVDPQ FLKLTKVDDQ IYSEFRKNFE TLRIDVLDPE ELKSESAKEK
110 120 130 140 150
WRPFCLKFNG IVEDFNYGTL LRLDCSQGYT EENTIFAPRI QFFAIEIARN
160 170 180 190 200
REGYNKAVYI SVQDKEGEKG VNNGGEKRAD SGEEENTKNG GEKGADSGEE
210 220 230
KEEGINREDK TDKGGEKGKE ADKEINKSGE KAM
Length:233
Mass (Da):26,057
Last modified:June 1, 2001 - v1
Checksum:i31FD39EC70B9A9C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC001220 mRNA. Translation: AAH01220.1.
BC051894 mRNA. Translation: AAH51894.1.
CCDSiCCDS14432.1.
RefSeqiNP_001287817.1. NM_001300888.1.
NP_057584.2. NM_016500.3.
UniGeneiHs.370100.

Genome annotation databases

EnsembliENST00000373358; ENSP00000362456; ENSG00000102390.
GeneIDi51260.
KEGGihsa:51260.
UCSCiuc004ecl.1. human.

Polymorphism databases

DMDMi74733325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC001220 mRNA. Translation: AAH01220.1.
BC051894 mRNA. Translation: AAH51894.1.
CCDSiCCDS14432.1.
RefSeqiNP_001287817.1. NM_001300888.1.
NP_057584.2. NM_016500.3.
UniGeneiHs.370100.

3D structure databases

ProteinModelPortaliQ9BVG4.
SMRiQ9BVG4. Positions 26-155.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119416. 14 interactions.
IntActiQ9BVG4. 6 interactions.
STRINGi9606.ENSP00000362456.

PTM databases

PhosphoSiteiQ9BVG4.

Polymorphism databases

DMDMi74733325.

Proteomic databases

MaxQBiQ9BVG4.
PaxDbiQ9BVG4.
PeptideAtlasiQ9BVG4.
PRIDEiQ9BVG4.

Protocols and materials databases

DNASUi51260.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000373358; ENSP00000362456; ENSG00000102390.
GeneIDi51260.
KEGGihsa:51260.
UCSCiuc004ecl.1. human.

Organism-specific databases

CTDi51260.
GeneCardsiGC0XP075409.
H-InvDBHIX0016884.
HIX0148004.
HGNCiHGNC:28790. PBDC1.
HPAiHPA003155.
neXtProtiNX_Q9BVG4.
PharmGKBiPA128394657.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG285457.
GeneTreeiENSGT00390000016333.
HOGENOMiHOG000189636.
HOVERGENiHBG059712.
InParanoidiQ9BVG4.
OMAiLRLNCSQ.
PhylomeDBiQ9BVG4.
TreeFamiTF314442.

Miscellaneous databases

GenomeRNAii51260.
NextBioi54431.

Gene expression databases

BgeeiQ9BVG4.
CleanExiHS_CXorf26.
ExpressionAtlasiQ9BVG4. baseline and differential.
GenevestigatoriQ9BVG4.

Family and domain databases

Gene3Di1.10.3560.10. 1 hit.
InterProiIPR021148. Put_polysacc_synth.
IPR008476. UPF0368_met/fun.
IPR023139. Yst0336-like_domain.
[Graphical view]
PANTHERiPTHR13410. PTHR13410. 1 hit.
PfamiPF04669. Polysacc_synt_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Leiomyosarcoma and Rhabdomyosarcoma.
  2. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-126, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  4. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
    Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
    Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-197, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181 AND SER-197, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiPBDC1_HUMAN
AccessioniPrimary (citable) accession number: Q9BVG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: January 7, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.