Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9BVC6 (TM109_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein 109
Alternative name(s):
Mitsugumin-23
Short name=Mg23
Gene names
Name:TMEM109
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length243 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333 Potential
Chain34 – 243210Transmembrane protein 109
PRO_0000044618

Regions

Transmembrane84 – 10421Helical; Potential
Transmembrane136 – 15621Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane186 – 20520Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9BVC6 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: E405591236B94BB3

FASTA24326,210
        10         20         30         40         50         60 
MAASSISSPW GKHVFKAILM VLVALILLHS ALAQSRRDFA PPGQQKREAP VDVLTQIGRS 

        70         80         90        100        110        120 
VRGTLDAWIG PETMHLVSES SSQVLWAISS AISVAFFALS GIAAQLLNAL GLAGDYLAQG 

       130        140        150        160        170        180 
LKLSPGQVQT FLLWGAGALV VYWLLSLLLG LVLALLGRIL WGLKLVIFLA GFVALMRSVP 

       190        200        210        220        230        240 
DPSTRALLLL ALLILYALLS RLTGSRASGA QLEAKVRGLE RQVEELRWRQ RRAAKGARSV 


EEE 

« Hide

References

« Hide 'large scale' references
[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Placenta.
[2]Bienvenut W.V., Claeys D.
Submitted (NOV-2005) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 48-59 AND 207-215, IDENTIFICATION BY MASS SPECTROMETRY.
Tissue: Platelet.
[3]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC001309 mRNA. Translation: AAH01309.1.
CCDSCCDS7996.1.
RefSeqNP_076997.1. NM_024092.2.
UniGeneHs.13662.

3D structure databases

ProteinModelPortalQ9BVC6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122524. 3 interactions.
IntActQ9BVC6. 6 interactions.
MINTMINT-5003515.
STRING9606.ENSP00000227525.

PTM databases

PhosphoSiteQ9BVC6.

Polymorphism databases

DMDM74733312.

Proteomic databases

MaxQBQ9BVC6.
PaxDbQ9BVC6.
PeptideAtlasQ9BVC6.
PRIDEQ9BVC6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000227525; ENSP00000227525; ENSG00000110108.
ENST00000536171; ENSP00000443990; ENSG00000110108.
GeneID79073.
KEGGhsa:79073.
UCSCuc001nqg.3. human.

Organism-specific databases

CTD79073.
GeneCardsGC11P060681.
HGNCHGNC:28771. TMEM109.
HPAHPA011785.
neXtProtNX_Q9BVC6.
PharmGKBPA142670760.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG46846.
HOGENOMHOG000126892.
HOVERGENHBG083664.
InParanoidQ9BVC6.
OMATMHLVSE.
OrthoDBEOG79CZ16.
PhylomeDBQ9BVC6.
TreeFamTF332238.

Gene expression databases

ArrayExpressQ9BVC6.
BgeeQ9BVC6.
CleanExHS_TMEM109.
GenevestigatorQ9BVC6.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi79073.
NextBio67865.
PROQ9BVC6.

Entry information

Entry nameTM109_HUMAN
AccessionPrimary (citable) accession number: Q9BVC6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM