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Q9BV19 (CA050_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C1orf50
Gene names
Name:C1orf50
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length199 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   DomainCoiled coil
   PTMAcetylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 199199Uncharacterized protein C1orf50
PRO_0000251189

Regions

Coiled coil71 – 10131 Potential

Amino acid modifications

Modified residue11N-acetylmethionine Ref.3

Natural variations

Natural variant1781T → M. Ref.2
Corresponds to variant rs11548275 [ dbSNP | Ensembl ].
VAR_054409

Sequences

Sequence LengthMass (Da)Tools
Q9BV19 [UniParc].

Last modified February 10, 2009. Version 2.
Checksum: 499A0179C042E39D

FASTA19921,877
        10         20         30         40         50         60 
MEDAAAPGRT EGVLERQGAP PAAGQGGALV ELTPTPGGLA LVSPYHTHRA GDPLDLVALA 

        70         80         90        100        110        120 
EQVQKADEFI RANATNKLTV IAEQIQHLQE QARKVLEDAH RDANLHHVAC NIVKKPGNIY 

       130        140        150        160        170        180 
YLYKRESGQQ YFSIISPKEW GTSCPHDFLG AYKLQHDLSW TPYEDIEKQD AKISMMDTLL 

       190 
SQSVALPPCT EPNFQGLTH 

« Hide

References

[1]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT MET-178.
Tissue: Lymph.
[3]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC098484 Genomic DNA. No translation available.
BC001508 mRNA. Translation: AAH01508.1.
BC001711 mRNA. Translation: AAH01711.1.
RefSeqNP_077002.2. NM_024097.3.
UniGeneHs.148845.

3D structure databases

ProteinModelPortalQ9BV19.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122528. 2 interactions.
IntActQ9BV19. 1 interaction.

PTM databases

PhosphoSiteQ9BV19.

Polymorphism databases

DMDM223590163.

Proteomic databases

PaxDbQ9BV19.
PRIDEQ9BV19.

Protocols and materials databases

DNASU79078.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000372525; ENSP00000361603; ENSG00000164008.
GeneID79078.
KEGGhsa:79078.
UCSCuc001cia.4. human.

Organism-specific databases

CTD79078.
GeneCardsGC01P043232.
HGNCHGNC:28795. C1orf50.
HPAHPA030236.
neXtProtNX_Q9BV19.
PharmGKBPA134861089.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG84695.
HOGENOMHOG000230218.
HOVERGENHBG080112.
InParanoidQ9BV19.
OMARANATNK.
PhylomeDBQ9BV19.
TreeFamTF105992.

Gene expression databases

ArrayExpressQ9BV19.
BgeeQ9BV19.
CleanExHS_C1orf50.
GenevestigatorQ9BV19.

Family and domain databases

InterProIPR019534. DUF2452.
[Graphical view]
PfamPF10504. DUF2452. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSC1orf50. human.
GenomeRNAi79078.
NextBio67879.

Entry information

Entry nameCA050_HUMAN
AccessionPrimary (citable) accession number: Q9BV19
Entry history
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: February 10, 2009
Last modified: April 16, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM