Q9BV19 (CA050_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C1orf50

Gene names

Name:

C1orf50

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	Uncharacterized protein C1orf50		PRO_0000251189
Regions
	Coiled coil	71 – 101	31	Potential
Natural variations
	Natural variant	178	1	T → M. Ref.2 Corresponds to variant rs11548275 [ dbSNP | Ensembl ].		VAR_054409

Sequences

	Sequence		Length	Mass (Da)
	Q9BV19 [UniParc]. Last modified February 10, 2009. Version 2. Checksum: 499A0179C042E39D	FASTA	199	21,877
	10 20 30 40 50 60 MEDAAAPGRT EGVLERQGAP PAAGQGGALV ELTPTPGGLA LVSPYHTHRA GDPLDLVALA 70 80 90 100 110 120 EQVQKADEFI RANATNKLTV IAEQIQHLQE QARKVLEDAH RDANLHHVAC NIVKKPGNIY 130 140 150 160 170 180 YLYKRESGQQ YFSIISPKEW GTSCPHDFLG AYKLQHDLSW TPYEDIEKQD AKISMMDTLL 190 SQSVALPPCT EPNFQGLTH

References

[1]

"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT MET-178. Tissue: Lymph.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC098484 Genomic DNA. No translation available. BC001508 mRNA. Translation: AAH01508.1. BC001711 mRNA. Translation: AAH01711.1.
IPI	IPI00012198.
RefSeq	NP_077002.2. NM_024097.3.
UniGene	Hs.148845.
3D structure databases
ProteinModelPortal	Q9BV19.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BV19. 1 interaction.
PTM databases
PhosphoSite	Q9BV19.
Polymorphism databases
DMDM	223590163.
Proteomic databases
PaxDb	Q9BV19.
PRIDE	Q9BV19.
Protocols and materials databases
DNASU	79078.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000372525; ENSP00000361603; ENSG00000164008.
GeneID	79078.
KEGG	hsa:79078.
UCSC	uc001cia.4. human.
Organism-specific databases
CTD	79078.
GeneCards	GC01P043232.
HGNC	HGNC:28795. C1orf50.
HPA	HPA030236.
neXtProt	NX_Q9BV19.
PharmGKB	PA134861089.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG84695.
HOGENOM	HOG000230218.
HOVERGEN	HBG080112.
InParanoid	Q9BV19.
OMA	YYLYKRE.
OrthoDB	EOG4RBQKQ.
Gene expression databases
ArrayExpress	Q9BV19.
Bgee	Q9BV19.
CleanEx	HS_C1orf50.
Genevestigator	Q9BV19.
GermOnline	ENSG00000164008. Homo sapiens.
Family and domain databases
InterPro	IPR019534. DUF2452. [Graphical view]
Pfam	PF10504. DUF2452. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	C1orf50. human.
GenomeRNAi	79078.
NextBio	67879.

Entry information

Entry name

CA050_HUMAN

Accession

Primary (citable) accession number: Q9BV19

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	February 10, 2009
Last modified:	April 3, 2013
This is version 74 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.