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Protein

Protein HGH1 homolog

Gene

HGH1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HGH1 homolog
Gene namesi
Name:HGH1
Synonyms:C8orf30A, C8orf30B, FAM203A, FAM203B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000235173.6.
HGNCiHGNC:24161. HGH1.

Pathology & Biotechi

Organism-specific databases

DisGeNETi51236.
OpenTargetsiENSG00000235173.
PharmGKBiPA142672348.
PA142672349.

Polymorphism and mutation databases

BioMutaiFAM203A.
DMDMi74733161.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00002733182 – 390Protein HGH1 homologAdd BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylglycineCombined sources1 Publication1
Modified residuei17PhosphoserineCombined sources1
Modified residuei214PhosphoserineCombined sources1
Modified residuei388PhosphothreonineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9BTY7.
MaxQBiQ9BTY7.
PaxDbiQ9BTY7.
PeptideAtlasiQ9BTY7.
PRIDEiQ9BTY7.

PTM databases

iPTMnetiQ9BTY7.
PhosphoSitePlusiQ9BTY7.

Expressioni

Gene expression databases

BgeeiENSG00000235173.
CleanExiHS_C8orf30A.
ExpressionAtlasiQ9BTY7. baseline and differential.
GenevisibleiQ9BTY7. HS.

Organism-specific databases

HPAiHPA042470.

Interactioni

Protein-protein interaction databases

BioGridi119398. 23 interactors.
IntActiQ9BTY7. 10 interactors.
MINTiMINT-1379236.
STRINGi9606.ENSP00000321320.

Structurei

3D structure databases

ProteinModelPortaliQ9BTY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi4 – 151Ala-richAdd BLAST148

Sequence similaritiesi

Belongs to the HGH1 family.Curated

Phylogenomic databases

eggNOGiKOG2973. Eukaryota.
ENOG410YNU7. LUCA.
GeneTreeiENSGT00390000016546.
HOVERGENiHBG060474.
InParanoidiQ9BTY7.
OMAiCLLACEN.
OrthoDBiEOG091G0DXE.
PhylomeDBiQ9BTY7.
TreeFamiTF313296.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR007206. Protein_HGH1_C.
IPR007205. Protein_HGH1_N.
PfamiView protein in Pfam
PF04063. DUF383. 1 hit.
PF04064. DUF384. 1 hit.
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BTY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEAGAGAGA SGGPEASPEA EVVKLLPFLA PGARADLQAA AVRHVLALTG
60 70 80 90 100
CGPGRALLAG QAALLQALME LAPASAPARD AARALVNLAA DPGLHETLLA
110 120 130 140 150
ADPGLPARLM GRALDPQWPW AEEAAAALAN LSREPAPCAA LMAALAAAEP
160 170 180 190 200
ADSGLERLVR ALCTPGYNAR APLHYLAPLL SNLSQRPAAR AFLLDPDRCV
210 220 230 240 250
VQRLLPLTQY PDSSVRRGGV VGTLRNCCFE HRHHEWLLGP EVDILPFLLL
260 270 280 290 300
PLAGPEDFSE EEMERLPVDL QYLPPDKQRE PDADIRKMLV EAIMLLTATA
310 320 330 340 350
PGRQQVRDQG AYLILRELHS WEPEPDVRTA CEKLIQVLIG DEPERGMENL
360 370 380 390
LEVQVPEDVE QQLQQLDCRE QEQLERELAP EPWVERATPT
Length:390
Mass (Da):42,129
Last modified:June 1, 2001 - v1
Checksum:iDC3AA4E92EA3761D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104592 Genomic DNA. No translation available.
BC003035 mRNA. Translation: AAH03035.1.
BC009915 mRNA. Translation: AAH09915.1.
CCDSiCCDS6417.1.
RefSeqiNP_057542.2. NM_016458.3.
UniGeneiHs.300224.

Genome annotation databases

EnsembliENST00000347708; ENSP00000321320; ENSG00000235173.
GeneIDi51236.
KEGGihsa:51236.
UCSCiuc010mfs.4. human.

Similar proteinsi

Entry informationi

Entry nameiHGH1_HUMAN
AccessioniPrimary (citable) accession number: Q9BTY7
Secondary accession number(s): P0CB43
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: June 1, 2001
Last modified: September 27, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families