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Protein

Zinc finger BED domain-containing protein 2

Gene

ZBED2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri52 – 113BED-typePROSITE-ProRule annotationAdd BLAST62

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger BED domain-containing protein 2
Gene namesi
Name:ZBED2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000177494.5
HGNCiHGNC:20710 ZBED2
MIMi615246 gene
neXtProtiNX_Q9BTP6

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000177494
PharmGKBiPA134879520

Polymorphism and mutation databases

BioMutaiZBED2
DMDMi251757414

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000665611 – 218Zinc finger BED domain-containing protein 2Add BLAST218

Proteomic databases

EPDiQ9BTP6
PaxDbiQ9BTP6
PeptideAtlasiQ9BTP6
PRIDEiQ9BTP6

PTM databases

iPTMnetiQ9BTP6
PhosphoSitePlusiQ9BTP6

Expressioni

Gene expression databases

BgeeiENSG00000177494
CleanExiHS_ZBED2
GenevisibleiQ9BTP6 HS

Organism-specific databases

HPAiHPA029786

Interactioni

Protein-protein interaction databases

BioGridi122663, 2 interactors
IntActiQ9BTP6, 2 interactors

Structurei

Secondary structure

1218
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi55 – 60Combined sources6
Beta strandi61 – 63Combined sources3
Beta strandi68 – 70Combined sources3
Beta strandi76 – 81Combined sources6
Beta strandi93 – 95Combined sources3
Helixi97 – 104Combined sources8
Helixi107 – 112Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DJRNMR-A55-117[»]
ProteinModelPortaliQ9BTP6
SMRiQ9BTP6
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9BTP6

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri52 – 113BED-typePROSITE-ProRule annotationAdd BLAST62

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IXJY Eukaryota
ENOG41115R7 LUCA
GeneTreeiENSGT00390000013530
HOGENOMiHOG000136530
InParanoidiQ9BTP6
OMAiTPMPHNK
OrthoDBiEOG091G0JGE
PhylomeDBiQ9BTP6
TreeFamiTF338048

Family and domain databases

InterProiView protein in InterPro
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
PfamiView protein in Pfam
PF02892 zf-BED, 1 hit
SMARTiView protein in SMART
SM00614 ZnF_BED, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50808 ZF_BED, 1 hit

Sequencei

Sequence statusi: Complete.

Q9BTP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMRREDEEEE GTMMKAKGDL EMKEEEEISE TGELVGPFVS AMPTPMPHNK
60 70 80 90 100
GTRFSEAWEY FHLAPARAGH HPNQYATCRL CGRQVSRGPG VNVGTTALWK
110 120 130 140 150
HLKSMHREEL EKSGHGQAGQ RQDPRPHGPQ LPTGIEGNWG RLLEQVGTMA
160 170 180 190 200
LWASQREKEV LRRERAVEWR ERAVEKRERA LEEVERAILE MKWKVRAEKE
210
ACQREKELPA AVHPFHFV
Length:218
Mass (Da):25,122
Last modified:July 7, 2009 - v2
Checksum:i2E2602FA7FC3BEE2
GO

Sequence cautioni

The sequence AAH03536 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH71956 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC055748 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW79699.1
CH471052 Genomic DNA Translation: EAW79700.1
BC003536 mRNA Translation: AAH03536.1 Different initiation.
BC071956 mRNA Translation: AAH71956.1 Different initiation.
CCDSiCCDS2960.2
RefSeqiNP_078784.2, NM_024508.4
UniGeneiHs.136912

Genome annotation databases

EnsembliENST00000317012; ENSP00000321370; ENSG00000177494
GeneIDi79413
KEGGihsa:79413
UCSCiuc003dxy.4 human

Similar proteinsi

Entry informationi

Entry nameiZBED2_HUMAN
AccessioniPrimary (citable) accession number: Q9BTP6
Secondary accession number(s): D3DN62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: July 7, 2009
Last modified: March 28, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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