Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger BED domain-containing protein 2

Gene

ZBED2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri52 – 11362BED-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger BED domain-containing protein 2
Gene namesi
Name:ZBED2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:20710. ZBED2.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134879520.

Polymorphism and mutation databases

BioMutaiZBED2.
DMDMi251757414.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Zinc finger BED domain-containing protein 2PRO_0000066561Add
BLAST

Proteomic databases

EPDiQ9BTP6.
PaxDbiQ9BTP6.
PRIDEiQ9BTP6.

PTM databases

iPTMnetiQ9BTP6.
PhosphoSiteiQ9BTP6.

Expressioni

Gene expression databases

BgeeiQ9BTP6.
CleanExiHS_ZBED2.
GenevisibleiQ9BTP6. HS.

Organism-specific databases

HPAiHPA029786.

Interactioni

Protein-protein interaction databases

BioGridi122663. 2 interactions.
IntActiQ9BTP6. 2 interactions.
STRINGi9606.ENSP00000321370.

Structurei

Secondary structure

1
218
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi55 – 606Combined sources
Beta strandi61 – 633Combined sources
Beta strandi68 – 703Combined sources
Beta strandi76 – 816Combined sources
Beta strandi93 – 953Combined sources
Helixi97 – 1048Combined sources
Helixi107 – 1126Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DJRNMR-A55-117[»]
ProteinModelPortaliQ9BTP6.
SMRiQ9BTP6. Positions 56-119.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9BTP6.

Family & Domainsi

Sequence similaritiesi

Contains 1 BED-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri52 – 11362BED-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IXJY. Eukaryota.
ENOG41115R7. LUCA.
GeneTreeiENSGT00390000013530.
HOGENOMiHOG000136530.
InParanoidiQ9BTP6.
OMAiPMPHNKG.
OrthoDBiEOG7HQN9C.
PhylomeDBiQ9BTP6.
TreeFamiTF338048.

Family and domain databases

InterProiIPR003656. Znf_BED.
[Graphical view]
PfamiPF02892. zf-BED. 1 hit.
[Graphical view]
SMARTiSM00614. ZnF_BED. 1 hit.
[Graphical view]
PROSITEiPS50808. ZF_BED. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BTP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMRREDEEEE GTMMKAKGDL EMKEEEEISE TGELVGPFVS AMPTPMPHNK
60 70 80 90 100
GTRFSEAWEY FHLAPARAGH HPNQYATCRL CGRQVSRGPG VNVGTTALWK
110 120 130 140 150
HLKSMHREEL EKSGHGQAGQ RQDPRPHGPQ LPTGIEGNWG RLLEQVGTMA
160 170 180 190 200
LWASQREKEV LRRERAVEWR ERAVEKRERA LEEVERAILE MKWKVRAEKE
210
ACQREKELPA AVHPFHFV
Length:218
Mass (Da):25,122
Last modified:July 7, 2009 - v2
Checksum:i2E2602FA7FC3BEE2
GO

Sequence cautioni

The sequence AAH03536.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAH71956.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC055748 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW79699.1.
CH471052 Genomic DNA. Translation: EAW79700.1.
BC003536 mRNA. Translation: AAH03536.1. Different initiation.
BC071956 mRNA. Translation: AAH71956.1. Different initiation.
CCDSiCCDS2960.2.
RefSeqiNP_078784.2. NM_024508.4.
UniGeneiHs.136912.

Genome annotation databases

EnsembliENST00000317012; ENSP00000321370; ENSG00000177494.
GeneIDi79413.
KEGGihsa:79413.
UCSCiuc003dxy.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC055748 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW79699.1.
CH471052 Genomic DNA. Translation: EAW79700.1.
BC003536 mRNA. Translation: AAH03536.1. Different initiation.
BC071956 mRNA. Translation: AAH71956.1. Different initiation.
CCDSiCCDS2960.2.
RefSeqiNP_078784.2. NM_024508.4.
UniGeneiHs.136912.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DJRNMR-A55-117[»]
ProteinModelPortaliQ9BTP6.
SMRiQ9BTP6. Positions 56-119.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122663. 2 interactions.
IntActiQ9BTP6. 2 interactions.
STRINGi9606.ENSP00000321370.

PTM databases

iPTMnetiQ9BTP6.
PhosphoSiteiQ9BTP6.

Polymorphism and mutation databases

BioMutaiZBED2.
DMDMi251757414.

Proteomic databases

EPDiQ9BTP6.
PaxDbiQ9BTP6.
PRIDEiQ9BTP6.

Protocols and materials databases

DNASUi79413.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000317012; ENSP00000321370; ENSG00000177494.
GeneIDi79413.
KEGGihsa:79413.
UCSCiuc003dxy.4. human.

Organism-specific databases

CTDi79413.
GeneCardsiZBED2.
HGNCiHGNC:20710. ZBED2.
HPAiHPA029786.
MIMi615246. gene.
neXtProtiNX_Q9BTP6.
PharmGKBiPA134879520.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IXJY. Eukaryota.
ENOG41115R7. LUCA.
GeneTreeiENSGT00390000013530.
HOGENOMiHOG000136530.
InParanoidiQ9BTP6.
OMAiPMPHNKG.
OrthoDBiEOG7HQN9C.
PhylomeDBiQ9BTP6.
TreeFamiTF338048.

Miscellaneous databases

EvolutionaryTraceiQ9BTP6.
GenomeRNAii79413.
NextBioi68375.
PROiQ9BTP6.
SOURCEiSearch...

Gene expression databases

BgeeiQ9BTP6.
CleanExiHS_ZBED2.
GenevisibleiQ9BTP6. HS.

Family and domain databases

InterProiIPR003656. Znf_BED.
[Graphical view]
PfamiPF02892. zf-BED. 1 hit.
[Graphical view]
SMARTiSM00614. ZnF_BED. 1 hit.
[Graphical view]
PROSITEiPS50808. ZF_BED. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary and Uterus.
  4. "Solution structures of the C2H2 type zinc finger domain of human zinc finger BED domain containing protein 2."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2006) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 55-117.

Entry informationi

Entry nameiZBED2_HUMAN
AccessioniPrimary (citable) accession number: Q9BTP6
Secondary accession number(s): D3DN62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: July 7, 2009
Last modified: March 16, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.