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Q9BTE7

- DCNL5_HUMAN

UniProt

Q9BTE7 - DCNL5_HUMAN

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Protein

DCN1-like protein 5

Gene
DCUN1D5
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
DCN1-like protein 5
Alternative name(s):
DCUN1 domain-containing protein 5
Defective in cullin neddylation protein 1-like protein 5
Gene namesi
Name:DCUN1D5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:28409. DCUN1D5.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672011.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237DCN1-like protein 5PRO_0000254171Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei9 – 91Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9BTE7.
PaxDbiQ9BTE7.
PeptideAtlasiQ9BTE7.
PRIDEiQ9BTE7.

PTM databases

PhosphoSiteiQ9BTE7.

Expressioni

Gene expression databases

ArrayExpressiQ9BTE7.
BgeeiQ9BTE7.
CleanExiHS_DCUN1D5.
GenevestigatoriQ9BTE7.

Organism-specific databases

HPAiHPA050863.

Interactioni

Protein-protein interaction databases

BioGridi123986. 13 interactions.
IntActiQ9BTE7. 1 interaction.
STRINGi9606.ENSP00000260247.

Structurei

3D structure databases

ProteinModelPortaliQ9BTE7.
SMRiQ9BTE7. Positions 65-232.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini46 – 232187DCUN1Add
BLAST

Sequence similaritiesi

Contains 1 DCUN1 domain.

Phylogenomic databases

eggNOGiNOG279481.
HOGENOMiHOG000241761.
HOVERGENiHBG106637.
InParanoidiQ9BTE7.
KOiK17824.
OMAiQCDSIQK.
PhylomeDBiQ9BTE7.
TreeFamiTF354270.

Family and domain databases

InterProiIPR014764. DCN-prot.
IPR005176. PONY_dom.
[Graphical view]
PANTHERiPTHR12281. PTHR12281. 1 hit.
PfamiPF03556. Cullin_binding. 1 hit.
[Graphical view]
PROSITEiPS51229. DCUN1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BTE7-1 [UniParc]FASTAAdd to Basket

« Hide

MPVKKKRKSP GVAAAVAEDG GLKKCKISSY CRSQPPARLI SGEEHFSSKK    50
CLAWFYEYAG PDEVVGPEGM EKFCEDIGVE PENIIMLVLA WKLEAESMGF 100
FTKEEWLKGM TSLQCDCTEK LQNKFDFLRS QLNDISSFKN IYRYAFDFAR 150
DKDQRSLDID TAKSMLALLL GRTWPLFSVF YQYLEQSKYR VMNKDQWYNV 200
LEFSRTVHAD LSNYDEDGAW PVLLDEFVEW QKVRQTS 237
Length:237
Mass (Da):27,508
Last modified:June 1, 2001 - v1
Checksum:i4F507B6E5D81EF79
GO

Sequence cautioni

The sequence AAQ76805.1 differs from that shown. Reason: Frameshift at positions 222 and 232.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti227 – 2271F → L in AAQ76805. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056993 mRNA. Translation: BAB71336.1.
BC004169 mRNA. Translation: AAH04169.1.
AY364246 mRNA. Translation: AAQ76805.1. Frameshift.
CCDSiCCDS8325.1.
RefSeqiNP_115675.1. NM_032299.3.
UniGeneiHs.503716.

Genome annotation databases

EnsembliENST00000260247; ENSP00000260247; ENSG00000137692.
GeneIDi84259.
KEGGihsa:84259.
UCSCiuc001phm.3. human.

Polymorphism databases

DMDMi74733117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056993 mRNA. Translation: BAB71336.1 .
BC004169 mRNA. Translation: AAH04169.1 .
AY364246 mRNA. Translation: AAQ76805.1 . Frameshift.
CCDSi CCDS8325.1.
RefSeqi NP_115675.1. NM_032299.3.
UniGenei Hs.503716.

3D structure databases

ProteinModelPortali Q9BTE7.
SMRi Q9BTE7. Positions 65-232.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123986. 13 interactions.
IntActi Q9BTE7. 1 interaction.
STRINGi 9606.ENSP00000260247.

PTM databases

PhosphoSitei Q9BTE7.

Polymorphism databases

DMDMi 74733117.

Proteomic databases

MaxQBi Q9BTE7.
PaxDbi Q9BTE7.
PeptideAtlasi Q9BTE7.
PRIDEi Q9BTE7.

Protocols and materials databases

DNASUi 84259.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000260247 ; ENSP00000260247 ; ENSG00000137692 .
GeneIDi 84259.
KEGGi hsa:84259.
UCSCi uc001phm.3. human.

Organism-specific databases

CTDi 84259.
GeneCardsi GC11M102924.
HGNCi HGNC:28409. DCUN1D5.
HPAi HPA050863.
neXtProti NX_Q9BTE7.
PharmGKBi PA142672011.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG279481.
HOGENOMi HOG000241761.
HOVERGENi HBG106637.
InParanoidi Q9BTE7.
KOi K17824.
OMAi QCDSIQK.
PhylomeDBi Q9BTE7.
TreeFami TF354270.

Miscellaneous databases

GenomeRNAii 84259.
NextBioi 73782.
PROi Q9BTE7.

Gene expression databases

ArrayExpressi Q9BTE7.
Bgeei Q9BTE7.
CleanExi HS_DCUN1D5.
Genevestigatori Q9BTE7.

Family and domain databases

InterProi IPR014764. DCN-prot.
IPR005176. PONY_dom.
[Graphical view ]
PANTHERi PTHR12281. PTHR12281. 1 hit.
Pfami PF03556. Cullin_binding. 1 hit.
[Graphical view ]
PROSITEi PS51229. DCUN1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Skeletal muscle.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.
  3. "NovelFam3000 -- uncharacterized human protein domains conserved across model organisms."
    Kemmer D., Podowski R.M., Arenillas D., Lim J., Hodges E., Roth P., Sonnhammer E.L.L., Hoeoeg C., Wasserman W.W.
    BMC Genomics 7:48-48(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-233.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiDCNL5_HUMAN
AccessioniPrimary (citable) accession number: Q9BTE7
Secondary accession number(s): Q3ZTT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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