Q9BT43 (RPC7L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase III subunit RPC7-like
Short name=RNA polymerase III subunit C7-like

Alternative name(s):
DNA-directed RNA polymerase III subunit G-like

Gene names

Name:

POLR3GL

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the eukaryotic RPC7 RNA polymerase subunit family.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	termination of RNA polymerase III transcription Traceable author statement. Source: Reactome transcription elongation from RNA polymerase III promoter Traceable author statement. Source: Reactome
Cellular_component	nucleoplasm Traceable author statement. Source: Reactome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	DNA-directed RNA polymerase III subunit RPC7-like		PRO_0000311590
Regions
	Compositional bias	142 – 191	50	Glu-rich
Amino acid modifications
	Modified residue	162	1	Phosphothreonine By similarity
	Modified residue	163	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9BT43 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 01E3B35D7279E43E	FASTA	218	25,334
	10 20 30 40 50 60 MASRGGGRGR GRGQLTFNVE AVGIGKGDAL PPPTLQPSPL FPPLEFRPVP LPSGEEGEYV 70 80 90 100 110 120 LALKQELRGA MRQLPYFIRP AVPKRDVERY SDKYQMSGPI DNAIDWNPDW RRLPRELKIR 130 140 150 160 170 180 VRKLQKERIT ILLPKRPPKT TEDKEETIQK LETLEKKEEE VTSEEDEEKE EEEEKEEEEE 190 200 210 EEYDEEEHEE ETDYIMSYFD NGEDFGGDSD DNMDEAIY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Two forms of RNA polymerase III with distinct expression patterns in human cells." Haurie V., Gaillard-Durrieu S., Prochazkova M., Dumay-Odelot H., Besser D., Teichmann M. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Skeletal muscle.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye.
[4]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ418461 mRNA. Translation: ABD76394.1. AK056984 mRNA. Translation: BAB71332.1. BC004355 mRNA. Translation: AAH04355.1.
IPI	IPI00031117.
RefSeq	NP_115681.1. NM_032305.1. XP_003960229.1. XM_003960180.1.
UniGene	Hs.591456.
3D structure databases
ProteinModelPortal	Q9BT43.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-59080N.
IntAct	Q9BT43. 1 interaction.
STRING	9606.ENSP00000358320.
PTM databases
PhosphoSite	Q9BT43.
Polymorphism databases
DMDM	74733087.
Proteomic databases
PaxDb	Q9BT43.
PRIDE	Q9BT43.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000369314; ENSP00000358320; ENSG00000121851.
GeneID	101060555. 84265.
KEGG	hsa:101060555. hsa:84265.
UCSC	uc001enp.1. human.
Organism-specific databases
CTD	84265.
GeneCards	GC01M145456.
HGNC	HGNC:28466. POLR3GL.
HPA	HPA027288.
neXtProt	NX_Q9BT43.
PharmGKB	PA134921690.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG77071.
HOGENOM	HOG000293249.
HOVERGEN	HBG054922.
InParanoid	Q9BT43.
KO	K03024.
OMA	FPPLEFH.
OrthoDB	EOG4V1725.
PhylomeDB	Q9BT43.
Enzyme and pathway databases
Reactome	REACT_1788. Transcription. REACT_71. Gene Expression.
Gene expression databases
ArrayExpress	Q9BT43.
Bgee	Q9BT43.
CleanEx	HS_POLR3GL.
Genevestigator	Q9BT43.
Family and domain databases
InterPro	IPR024661. RNA_pol_III_Rpc31. [Graphical view]
Pfam	PF11705. RNA_pol_3_Rpc31. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	73808.

Entry information

Entry name

RPC7L_HUMAN

Accession

Primary (citable) accession number: Q9BT43
Secondary accession number(s): B1MVG5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.