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Protein

Protein YIPF4

Gene

YIPF4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the maintenance of the Golgi structure.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIPF4
Alternative name(s):
YIP1 family member 4
Gene namesi
Name:YIPF4
ORF Names:Nbla11189
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:28145. YIPF4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei114 – 13421HelicalSequence analysisAdd
BLAST
Transmembranei139 – 15921HelicalSequence analysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence analysisAdd
BLAST
Transmembranei196 – 21621HelicalSequence analysisAdd
BLAST
Transmembranei224 – 24421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670547.

Polymorphism and mutation databases

BioMutaiYIPF4.
DMDMi74733045.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244Protein YIPF4PRO_0000242632Add
BLAST

Proteomic databases

EPDiQ9BSR8.
MaxQBiQ9BSR8.
PaxDbiQ9BSR8.
PRIDEiQ9BSR8.

PTM databases

iPTMnetiQ9BSR8.
PhosphoSiteiQ9BSR8.

Expressioni

Gene expression databases

BgeeiQ9BSR8.
CleanExiHS_YIPF4.
ExpressionAtlasiQ9BSR8. baseline and differential.
GenevisibleiQ9BSR8. HS.

Organism-specific databases

HPAiHPA017884.

Interactioni

Subunit structurei

Interacts with YIPF3.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
FATE1Q969F03EBI-751253,EBI-743099
RNF185Q96GF13EBI-751253,EBI-2340249
YIPF3Q9GZM54EBI-751253,EBI-743787

Protein-protein interaction databases

BioGridi123999. 21 interactions.
IntActiQ9BSR8. 5 interactions.
MINTiMINT-1454288.
STRINGi9606.ENSP00000238831.

Structurei

3D structure databases

ProteinModelPortaliQ9BSR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IQ6V. Eukaryota.
ENOG4111EZE. LUCA.
GeneTreeiENSGT00730000111152.
HOGENOMiHOG000285931.
HOVERGENiHBG056534.
InParanoidiQ9BSR8.
OMAiFSMISIY.
OrthoDBiEOG7GXPCN.
PhylomeDBiQ9BSR8.
TreeFamiTF315055.

Family and domain databases

InterProiIPR006977. Yip1.
[Graphical view]
PfamiPF04893. Yip1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BSR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPPGPPPAY APTNGDFTFV SSADAEDLSG SIASPDVKLN LGGDFIKEST
60 70 80 90 100
ATTFLRQRGY GWLLEVEDDD PEDNKPLLEE LDIDLKDIYY KIRCVLMPMP
110 120 130 140 150
SLGFNRQVVR DNPDFWGPLA VVLFFSMISL YGQFRVVSWI ITIWIFGSLT
160 170 180 190 200
IFLLARVLGG EVAYGQVLGV IGYSLLPLIV IAPVLLVVGS FEVVSTLIKL
210 220 230 240
FGVFWAAYSA ASLLVGEEFK TKKPLLIYPI FLLYIYFLSL YTGV
Length:244
Mass (Da):27,083
Last modified:June 1, 2001 - v1
Checksum:iBEC6F8EA9892F612
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB072898 mRNA. Translation: BAE45710.1.
AK098486 mRNA. Translation: BAC05315.1.
BC004875 mRNA. Translation: AAH04875.1.
CCDSiCCDS1781.1.
RefSeqiNP_115688.1. NM_032312.3.
UniGeneiHs.468099.

Genome annotation databases

EnsembliENST00000238831; ENSP00000238831; ENSG00000119820.
GeneIDi84272.
KEGGihsa:84272.
UCSCiuc002rok.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB072898 mRNA. Translation: BAE45710.1.
AK098486 mRNA. Translation: BAC05315.1.
BC004875 mRNA. Translation: AAH04875.1.
CCDSiCCDS1781.1.
RefSeqiNP_115688.1. NM_032312.3.
UniGeneiHs.468099.

3D structure databases

ProteinModelPortaliQ9BSR8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123999. 21 interactions.
IntActiQ9BSR8. 5 interactions.
MINTiMINT-1454288.
STRINGi9606.ENSP00000238831.

PTM databases

iPTMnetiQ9BSR8.
PhosphoSiteiQ9BSR8.

Polymorphism and mutation databases

BioMutaiYIPF4.
DMDMi74733045.

Proteomic databases

EPDiQ9BSR8.
MaxQBiQ9BSR8.
PaxDbiQ9BSR8.
PRIDEiQ9BSR8.

Protocols and materials databases

DNASUi84272.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000238831; ENSP00000238831; ENSG00000119820.
GeneIDi84272.
KEGGihsa:84272.
UCSCiuc002rok.4. human.

Organism-specific databases

CTDi84272.
GeneCardsiYIPF4.
HGNCiHGNC:28145. YIPF4.
HPAiHPA017884.
neXtProtiNX_Q9BSR8.
PharmGKBiPA142670547.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IQ6V. Eukaryota.
ENOG4111EZE. LUCA.
GeneTreeiENSGT00730000111152.
HOGENOMiHOG000285931.
HOVERGENiHBG056534.
InParanoidiQ9BSR8.
OMAiFSMISIY.
OrthoDBiEOG7GXPCN.
PhylomeDBiQ9BSR8.
TreeFamiTF315055.

Miscellaneous databases

ChiTaRSiYIPF4. human.
GeneWikiiYIPF4.
GenomeRNAii84272.
NextBioi73838.
PROiQ9BSR8.

Gene expression databases

BgeeiQ9BSR8.
CleanExiHS_YIPF4.
ExpressionAtlasiQ9BSR8. baseline and differential.
GenevisibleiQ9BSR8. HS.

Family and domain databases

InterProiIPR006977. Yip1.
[Graphical view]
PfamiPF04893. Yip1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma."
    Ohira M., Morohashi A., Nakamura Y., Isogai E., Furuya K., Hamano S., Machida T., Aoyama M., Fukumura M., Miyazaki K., Suzuki Y., Sugano S., Hirato J., Nakagawara A.
    Cancer Lett. 197:63-68(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Neuroblastoma.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Gastric mucosa.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lymph.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH YIPF4.

Entry informationi

Entry nameiYIPF4_HUMAN
AccessioniPrimary (citable) accession number: Q9BSR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2001
Last modified: April 13, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.