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Protein

Protein NipSnap homolog 3B

Gene

NIPSNAP3B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NipSnap homolog 3B
Short name:
NipSnap3B
Alternative name(s):
SNAP1
Gene namesi
Name:NIPSNAP3B
Synonyms:NIPSNAP3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:23641. NIPSNAP3B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134947095.

Polymorphism and mutation databases

BioMutaiNIPSNAP3B.
DMDMi17380145.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Protein NipSnap homolog 3BPRO_0000221154Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei45 – 451N6-succinyllysineBy similarity
Modified residuei57 – 571N6-succinyllysineBy similarity

Proteomic databases

EPDiQ9BS92.
MaxQBiQ9BS92.
PaxDbiQ9BS92.
PRIDEiQ9BS92.

PTM databases

iPTMnetiQ9BS92.
PhosphoSiteiQ9BS92.

Expressioni

Gene expression databases

BgeeiQ9BS92.
CleanExiHS_NIPSNAP3B.
ExpressionAtlasiQ9BS92. baseline and differential.
GenevisibleiQ9BS92. HS.

Organism-specific databases

HPAiHPA042491.
HPA047909.
HPA047925.
HPA049256.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000363894.

Structurei

3D structure databases

ProteinModelPortaliQ9BS92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NipSnap family.Curated

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000111003.
HOGENOMiHOG000007437.
HOVERGENiHBG052660.
InParanoidiQ9BS92.
OMAiKDKEWQQ.
PhylomeDBiQ9BS92.
TreeFamiTF314501.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 2 hits.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9BS92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVLRSGLTK ALASRTLAPQ VCSSFATGPR QYDGTFYEFR TYYLKPSNMN
60 70 80 90 100
AFMENLKKNI HLRTSYSELV GFWSVEFGGR TNKVFHIWKY DNFAHRAEVR
110 120 130 140 150
KALANCKEWQ EQSIIPNLAR IDKQETEITY LIPWSKLEKP PKEGVYELAV
160 170 180 190 200
FQMKPGGPAL WGDAFERAIN AHVNLGYTKV VGVFHTEYGE LNRVHVLWWN
210 220 230 240
ESADSRAAGR HKSHEDPRVV AAVRESVNYL VSQQNMLLIP ASFSPLK
Length:247
Mass (Da):28,313
Last modified:June 1, 2001 - v1
Checksum:i3D979E5AD99FC318
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti190 – 1901E → G in BAA92101 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti94 – 941A → P.1 Publication
Corresponds to variant rs10761084 [ dbSNP | Ensembl ].
VAR_050277
Natural varianti154 – 1541K → E.
Corresponds to variant rs3739740 [ dbSNP | Ensembl ].
VAR_050278
Natural varianti159 – 1591A → G.1 Publication
Corresponds to variant rs3739741 [ dbSNP | Ensembl ].
VAR_050279

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF287262 Genomic DNA. Translation: AAK43527.1.
AK002137 mRNA. Translation: BAA92101.1.
AL359846 Genomic DNA. Translation: CAH73582.1.
CH471105 Genomic DNA. Translation: EAW58991.1.
BC005202 mRNA. Translation: AAH05202.1.
BC017914 mRNA. Translation: AAH17914.1.
CCDSiCCDS6761.1.
RefSeqiNP_060846.2. NM_018376.3.
UniGeneiHs.429294.
Hs.720355.
Hs.732606.

Genome annotation databases

EnsembliENST00000374762; ENSP00000363894; ENSG00000165028.
GeneIDi55335.
KEGGihsa:55335.
UCSCiuc004bci.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF287262 Genomic DNA. Translation: AAK43527.1.
AK002137 mRNA. Translation: BAA92101.1.
AL359846 Genomic DNA. Translation: CAH73582.1.
CH471105 Genomic DNA. Translation: EAW58991.1.
BC005202 mRNA. Translation: AAH05202.1.
BC017914 mRNA. Translation: AAH17914.1.
CCDSiCCDS6761.1.
RefSeqiNP_060846.2. NM_018376.3.
UniGeneiHs.429294.
Hs.720355.
Hs.732606.

3D structure databases

ProteinModelPortaliQ9BS92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000363894.

PTM databases

iPTMnetiQ9BS92.
PhosphoSiteiQ9BS92.

Polymorphism and mutation databases

BioMutaiNIPSNAP3B.
DMDMi17380145.

Proteomic databases

EPDiQ9BS92.
MaxQBiQ9BS92.
PaxDbiQ9BS92.
PRIDEiQ9BS92.

Protocols and materials databases

DNASUi55335.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000374762; ENSP00000363894; ENSG00000165028.
GeneIDi55335.
KEGGihsa:55335.
UCSCiuc004bci.3. human.

Organism-specific databases

CTDi55335.
GeneCardsiNIPSNAP3B.
HGNCiHGNC:23641. NIPSNAP3B.
HPAiHPA042491.
HPA047909.
HPA047925.
HPA049256.
MIMi608872. gene.
neXtProtiNX_Q9BS92.
PharmGKBiPA134947095.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000111003.
HOGENOMiHOG000007437.
HOVERGENiHBG052660.
InParanoidiQ9BS92.
OMAiKDKEWQQ.
PhylomeDBiQ9BS92.
TreeFamiTF314501.

Miscellaneous databases

GenomeRNAii55335.
PROiQ9BS92.
SOURCEiSearch...

Gene expression databases

BgeeiQ9BS92.
CleanExiHS_NIPSNAP3B.
ExpressionAtlasiQ9BS92. baseline and differential.
GenevisibleiQ9BS92. HS.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 2 hits.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences."
    Qiu Y., Cavelier L., Chiu S., Yang X., Rubin E., Cheng J.-F.
    Genomics 73:66-76(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS PRO-94 AND GLY-159.
    Tissue: Placenta.
  3. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart and Skeletal muscle.

Entry informationi

Entry nameiNPS3B_HUMAN
AccessioniPrimary (citable) accession number: Q9BS92
Secondary accession number(s): Q5VX30, Q9NUM2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.