Q9BRT6 (LLPH_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein LLP homolog

Alternative name(s):
Protein LAPS18-like

Gene names

Name:	LLPH
Synonyms:	C12orf31

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	129 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the learning-associated protein family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 129	129	Protein LLP homolog		PRO_0000274346
Regions
	Compositional bias	3 – 125	123	Lys-rich
Experimental info
	Sequence conflict	76	1	E → G in AAI07781. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9BRT6 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 71C2CE6F79B63E4D	FASTA	129	15,225
	10 20 30 40 50 60 MAKSLRSKWK RKMRAEKRKK NAPKEASRLK SILKLDGDVL MKDVQEIATV VVPKPKHCQE 70 80 90 100 110 120 KMQCEVKDEK DDMKMETDIK RNKKTLLDQH GQYPIWMNQR QRKRLKAKRE KRKGKSKAKA VKVAKGLAW

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney and Skeletal muscle.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK091568 mRNA. Translation: BAC03699.1. BC006002 mRNA. Translation: AAH06002.1. BC070232 mRNA. Translation: AAH70232.1. BC107780 mRNA. Translation: AAI07781.1.
IPI	IPI00031615.
RefSeq	NP_115714.1. NM_032338.3.
UniGene	Hs.504820.
3D structure databases
ProteinModelPortal	Q9BRT6.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BRT6. 2 interactions.
MINT	MINT-1468069.
STRING	9606.ENSP00000266604.
PTM databases
PhosphoSite	Q9BRT6.
Polymorphism databases
DMDM	74732927.
Proteomic databases
PaxDb	Q9BRT6.
PRIDE	Q9BRT6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000266604; ENSP00000266604; ENSG00000139233. ENST00000446587; ENSP00000437372; ENSG00000139233.
GeneID	84298.
KEGG	hsa:84298.
UCSC	uc010ssw.2. human.
Organism-specific databases
CTD	84298.
GeneCards	GC12M066516.
HGNC	HGNC:28229. LLPH.
neXtProt	NX_Q9BRT6.
PharmGKB	PA164722116.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG299149.
HOGENOM	HOG000004847.
HOVERGEN	HBG081232.
InParanoid	Q9BRT6.
OMA	GQYPVWM.
OrthoDB	EOG4N04GJ.
PhylomeDB	Q9BRT6.
Gene expression databases
Bgee	Q9BRT6.
CleanEx	HS_LLPH.
Genevestigator	Q9BRT6.
Family and domain databases
InterPro	IPR018784. LAPS18-like. [Graphical view]
Pfam	PF10169. Laps. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LLPH. human.
GenomeRNAi	84298.
NextBio	73956.

Entry information

Entry name

LLPH_HUMAN

Accession

Primary (citable) accession number: Q9BRT6
Secondary accession number(s): Q3B766

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.