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Protein

Protein LLP homolog

Gene

LLPH

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LLP homolog
Alternative name(s):
Protein LAPS18-like
Gene namesi
Name:LLPH
Synonyms:C12orf31
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:28229. LLPH.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164722116.

Polymorphism and mutation databases

BioMutaiLLPH.
DMDMi74732927.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 129129Protein LLP homologPRO_0000274346Add
BLAST

Proteomic databases

MaxQBiQ9BRT6.
PaxDbiQ9BRT6.
PRIDEiQ9BRT6.

PTM databases

PhosphoSiteiQ9BRT6.

Expressioni

Gene expression databases

BgeeiQ9BRT6.
CleanExiHS_LLPH.
ExpressionAtlasiQ9BRT6. baseline and differential.
GenevisibleiQ9BRT6. HS.

Interactioni

Protein-protein interaction databases

BioGridi124024. 12 interactions.
IntActiQ9BRT6. 4 interactions.
MINTiMINT-1468069.
STRINGi9606.ENSP00000266604.

Structurei

3D structure databases

ProteinModelPortaliQ9BRT6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi3 – 125123Lys-richAdd
BLAST

Sequence similaritiesi

Belongs to the learning-associated protein family.Curated

Phylogenomic databases

eggNOGiNOG299149.
GeneTreeiENSGT00390000012979.
HOGENOMiHOG000004847.
HOVERGENiHBG081232.
InParanoidiQ9BRT6.
OMAiQYPVWMN.
OrthoDBiEOG76T9V7.
PhylomeDBiQ9BRT6.
TreeFamiTF314654.

Family and domain databases

InterProiIPR018784. LAPS18-like.
[Graphical view]
PfamiPF10169. Laps. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BRT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKSLRSKWK RKMRAEKRKK NAPKEASRLK SILKLDGDVL MKDVQEIATV
60 70 80 90 100
VVPKPKHCQE KMQCEVKDEK DDMKMETDIK RNKKTLLDQH GQYPIWMNQR
110 120
QRKRLKAKRE KRKGKSKAKA VKVAKGLAW
Length:129
Mass (Da):15,225
Last modified:June 1, 2001 - v1
Checksum:i71C2CE6F79B63E4D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti76 – 761E → G in AAI07781 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK091568 mRNA. Translation: BAC03699.1.
BC006002 mRNA. Translation: AAH06002.1.
BC070232 mRNA. Translation: AAH70232.1.
BC107780 mRNA. Translation: AAI07781.1.
CCDSiCCDS8974.1.
RefSeqiNP_115714.1. NM_032338.3.
UniGeneiHs.504820.

Genome annotation databases

EnsembliENST00000266604; ENSP00000266604; ENSG00000139233.
ENST00000446587; ENSP00000437372; ENSG00000139233.
GeneIDi84298.
KEGGihsa:84298.
UCSCiuc010ssw.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK091568 mRNA. Translation: BAC03699.1.
BC006002 mRNA. Translation: AAH06002.1.
BC070232 mRNA. Translation: AAH70232.1.
BC107780 mRNA. Translation: AAI07781.1.
CCDSiCCDS8974.1.
RefSeqiNP_115714.1. NM_032338.3.
UniGeneiHs.504820.

3D structure databases

ProteinModelPortaliQ9BRT6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124024. 12 interactions.
IntActiQ9BRT6. 4 interactions.
MINTiMINT-1468069.
STRINGi9606.ENSP00000266604.

PTM databases

PhosphoSiteiQ9BRT6.

Polymorphism and mutation databases

BioMutaiLLPH.
DMDMi74732927.

Proteomic databases

MaxQBiQ9BRT6.
PaxDbiQ9BRT6.
PRIDEiQ9BRT6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000266604; ENSP00000266604; ENSG00000139233.
ENST00000446587; ENSP00000437372; ENSG00000139233.
GeneIDi84298.
KEGGihsa:84298.
UCSCiuc010ssw.2. human.

Organism-specific databases

CTDi84298.
GeneCardsiGC12M066516.
HGNCiHGNC:28229. LLPH.
neXtProtiNX_Q9BRT6.
PharmGKBiPA164722116.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG299149.
GeneTreeiENSGT00390000012979.
HOGENOMiHOG000004847.
HOVERGENiHBG081232.
InParanoidiQ9BRT6.
OMAiQYPVWMN.
OrthoDBiEOG76T9V7.
PhylomeDBiQ9BRT6.
TreeFamiTF314654.

Miscellaneous databases

ChiTaRSiLLPH. human.
GenomeRNAii84298.
NextBioi73956.
PROiQ9BRT6.

Gene expression databases

BgeeiQ9BRT6.
CleanExiHS_LLPH.
ExpressionAtlasiQ9BRT6. baseline and differential.
GenevisibleiQ9BRT6. HS.

Family and domain databases

InterProiIPR018784. LAPS18-like.
[Graphical view]
PfamiPF10169. Laps. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney and Skeletal muscle.

Entry informationi

Entry nameiLLPH_HUMAN
AccessioniPrimary (citable) accession number: Q9BRT6
Secondary accession number(s): Q3B766
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: June 1, 2001
Last modified: July 22, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.