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Q9BRT6 (LLPH_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein LLP homolog
Alternative name(s):
Protein LAPS18-like
Gene names
Name:LLPH
Synonyms:C12orf31
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length129 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the learning-associated protein family.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionpoly(A) RNA binding

Inferred from direct assay PubMed 22658674PubMed 22681889. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 129129Protein LLP homolog
PRO_0000274346

Regions

Compositional bias3 – 125123Lys-rich

Experimental info

Sequence conflict761E → G in AAI07781. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9BRT6 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 71C2CE6F79B63E4D

FASTA12915,225
        10         20         30         40         50         60 
MAKSLRSKWK RKMRAEKRKK NAPKEASRLK SILKLDGDVL MKDVQEIATV VVPKPKHCQE 

        70         80         90        100        110        120 
KMQCEVKDEK DDMKMETDIK RNKKTLLDQH GQYPIWMNQR QRKRLKAKRE KRKGKSKAKA 


VKVAKGLAW 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney and Skeletal muscle.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK091568 mRNA. Translation: BAC03699.1.
BC006002 mRNA. Translation: AAH06002.1.
BC070232 mRNA. Translation: AAH70232.1.
BC107780 mRNA. Translation: AAI07781.1.
CCDSCCDS8974.1.
RefSeqNP_115714.1. NM_032338.3.
UniGeneHs.504820.

3D structure databases

ProteinModelPortalQ9BRT6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid124024. 5 interactions.
IntActQ9BRT6. 3 interactions.
MINTMINT-1468069.
STRING9606.ENSP00000266604.

PTM databases

PhosphoSiteQ9BRT6.

Polymorphism databases

DMDM74732927.

Proteomic databases

MaxQBQ9BRT6.
PaxDbQ9BRT6.
PRIDEQ9BRT6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000266604; ENSP00000266604; ENSG00000139233.
ENST00000446587; ENSP00000437372; ENSG00000139233.
GeneID84298.
KEGGhsa:84298.
UCSCuc010ssw.2. human.

Organism-specific databases

CTD84298.
GeneCardsGC12M066516.
HGNCHGNC:28229. LLPH.
neXtProtNX_Q9BRT6.
PharmGKBPA164722116.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG299149.
HOGENOMHOG000004847.
HOVERGENHBG081232.
InParanoidQ9BRT6.
OMAQYPVWMN.
OrthoDBEOG76T9V7.
PhylomeDBQ9BRT6.
TreeFamTF314654.

Gene expression databases

BgeeQ9BRT6.
CleanExHS_LLPH.
GenevestigatorQ9BRT6.

Family and domain databases

InterProIPR018784. LAPS18-like.
[Graphical view]
PfamPF10169. Laps. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSLLPH. human.
GenomeRNAi84298.
NextBio73956.
PROQ9BRT6.

Entry information

Entry nameLLPH_HUMAN
AccessionPrimary (citable) accession number: Q9BRT6
Secondary accession number(s): Q3B766
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 12

Human chromosome 12: entries, gene names and cross-references to MIM