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Protein
Submitted name:

TDP1 protein

Gene

TDP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TDP1 proteinImported
Submitted name:
Tyrosyl-DNA phosphodiesterase 1Imported
Gene namesi
Name:TDP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000042088.13
HGNCiHGNC:18884 TDP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042088

PTM / Processingi

Proteomic databases

MaxQBiQ9BRS7
PRIDEiQ9BRS7

Expressioni

Gene expression databases

BgeeiENSG00000042088
ExpressionAtlasiQ9BRS7 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2031 Eukaryota
ENOG410XQPZ LUCA
GeneTreeiENSGT00390000002211

Family and domain databases

InterProiView protein in InterPro
IPR010347 Tdp1
PANTHERiPTHR12415 PTHR12415, 1 hit
PfamiView protein in Pfam
PF06087 Tyr-DNA_phospho, 1 hit

Sequencei

Sequence statusi: Complete.

Q9BRS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE
60 70 80 90 100
AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM
110 120 130 140 150
PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE EEDEYETSGE
160 170 180 190 200
GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA
210 220 230 240 250
QFNYCFDVDW LVKQYPPEFR KKPILLVHGD KREAKAHLHA QAKPYENISL
260 270 280 290
CQAKLDIAFG THHTKMMLLL YEEGLRVVIH TSNLIHADWH QKTQGTHL
Length:298
Mass (Da):33,646
Last modified:June 1, 2001 - v1
Checksum:iC87ABB7048BBE56D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137128 Genomic DNA No translation available.
BC006083 mRNA Translation: AAH06083.1
UniGeneiHs.209945

Genome annotation databases

EnsembliENST00000545686; ENSP00000444587; ENSG00000042088
UCSCiuc059efq.1 human

Similar proteinsi

Entry informationi

Entry nameiQ9BRS7_HUMAN
AccessioniPrimary (citable) accession number: Q9BRS7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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