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Protein

Uncharacterized protein C7orf50

Gene

C7orf50

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:ENSG00000146540-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C7orf50
Gene namesi
Name:C7orf50
ORF Names:FP15621
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:22421. C7orf50.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000146540.
PharmGKBiPA162380546.

Polymorphism and mutation databases

BioMutaiC7orf50.
DMDMi74732893.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003095101 – 194Uncharacterized protein C7orf50Add BLAST194

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei23PhosphoserineCombined sources1
Modified residuei59PhosphoserineCombined sources1
Modified residuei97PhosphoserineCombined sources1
Modified residuei175PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9BRJ6.
MaxQBiQ9BRJ6.
PaxDbiQ9BRJ6.
PeptideAtlasiQ9BRJ6.
PRIDEiQ9BRJ6.

PTM databases

iPTMnetiQ9BRJ6.
PhosphoSitePlusiQ9BRJ6.

Expressioni

Gene expression databases

BgeeiENSG00000146540.
CleanExiHS_C7orf50.
ExpressionAtlasiQ9BRJ6. baseline and differential.
GenevisibleiQ9BRJ6. HS.

Organism-specific databases

HPAiHPA052281.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
THAP1Q9NVV93EBI-751612,EBI-741515

Protein-protein interaction databases

BioGridi124036. 26 interactors.
IntActiQ9BRJ6. 12 interactors.
MINTiMINT-5003494.
STRINGi9606.ENSP00000350011.

Structurei

3D structure databases

ProteinModelPortaliQ9BRJ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4829. Eukaryota.
ENOG411268U. LUCA.
GeneTreeiENSGT00390000017838.
HOGENOMiHOG000111595.
HOVERGENiHBG107666.
InParanoidiQ9BRJ6.
OMAiMYDRDKV.
OrthoDBiEOG091G0O74.
PhylomeDBiQ9BRJ6.
TreeFamiTF326634.

Family and domain databases

InterProiIPR019327. DUF2373.
[Graphical view]
PfamiPF10180. DUF2373. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BRJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQKRKVPE VTEKKNKKLK KASAEGPLLG PEAAPSGEGA GSKGEAVLRP
60 70 80 90 100
GLDAEPELSP EEQRVLERKL KKERKKEERQ RLREAGLVAQ HPPARRSGAE
110 120 130 140 150
LALDYLCRWA QKHKNWRFQK TRQTWLLLHM YDSDKVPDEH FSTLLAYLEG
160 170 180 190
LQGRARELTV QKAEALMREL DEEGSDPPLP GRAQRIRQVL QLLS
Length:194
Mass (Da):22,083
Last modified:June 1, 2001 - v1
Checksum:iEDFF8B6A335416F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF495721 mRNA. Translation: AAQ06675.1.
BC006224 mRNA. Translation: AAH06224.1.
CCDSiCCDS5320.1.
RefSeqiNP_001127867.1. NM_001134395.1.
NP_001127868.1. NM_001134396.1.
NP_001305181.1. NM_001318252.1.
NP_115726.1. NM_032350.5.
UniGeneiHs.653258.
Hs.732316.

Genome annotation databases

EnsembliENST00000357429; ENSP00000350011; ENSG00000146540.
ENST00000397098; ENSP00000380286; ENSG00000146540.
ENST00000397100; ENSP00000380288; ENSG00000146540.
GeneIDi84310.
KEGGihsa:84310.
UCSCiuc003sju.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF495721 mRNA. Translation: AAQ06675.1.
BC006224 mRNA. Translation: AAH06224.1.
CCDSiCCDS5320.1.
RefSeqiNP_001127867.1. NM_001134395.1.
NP_001127868.1. NM_001134396.1.
NP_001305181.1. NM_001318252.1.
NP_115726.1. NM_032350.5.
UniGeneiHs.653258.
Hs.732316.

3D structure databases

ProteinModelPortaliQ9BRJ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124036. 26 interactors.
IntActiQ9BRJ6. 12 interactors.
MINTiMINT-5003494.
STRINGi9606.ENSP00000350011.

PTM databases

iPTMnetiQ9BRJ6.
PhosphoSitePlusiQ9BRJ6.

Polymorphism and mutation databases

BioMutaiC7orf50.
DMDMi74732893.

Proteomic databases

EPDiQ9BRJ6.
MaxQBiQ9BRJ6.
PaxDbiQ9BRJ6.
PeptideAtlasiQ9BRJ6.
PRIDEiQ9BRJ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000357429; ENSP00000350011; ENSG00000146540.
ENST00000397098; ENSP00000380286; ENSG00000146540.
ENST00000397100; ENSP00000380288; ENSG00000146540.
GeneIDi84310.
KEGGihsa:84310.
UCSCiuc003sju.3. human.

Organism-specific databases

CTDi84310.
GeneCardsiC7orf50.
H-InvDBHIX0006412.
HGNCiHGNC:22421. C7orf50.
HPAiHPA052281.
neXtProtiNX_Q9BRJ6.
OpenTargetsiENSG00000146540.
PharmGKBiPA162380546.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4829. Eukaryota.
ENOG411268U. LUCA.
GeneTreeiENSGT00390000017838.
HOGENOMiHOG000111595.
HOVERGENiHBG107666.
InParanoidiQ9BRJ6.
OMAiMYDRDKV.
OrthoDBiEOG091G0O74.
PhylomeDBiQ9BRJ6.
TreeFamiTF326634.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000146540-MONOMER.

Miscellaneous databases

ChiTaRSiC7orf50. human.
GenomeRNAii84310.
PROiQ9BRJ6.

Gene expression databases

BgeeiENSG00000146540.
CleanExiHS_C7orf50.
ExpressionAtlasiQ9BRJ6. baseline and differential.
GenevisibleiQ9BRJ6. HS.

Family and domain databases

InterProiIPR019327. DUF2373.
[Graphical view]
PfamiPF10180. DUF2373. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCG050_HUMAN
AccessioniPrimary (citable) accession number: Q9BRJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.