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Q9BR26 (CT123_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transmembrane protein C20orf123
Gene names
Name:C20orf123
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length566 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
   Cellular componentMembrane
   Coding sequence diversityPolymorphism
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 566566Transmembrane protein C20orf123
PRO_0000342121

Regions

Transmembrane52 – 7221Helical; Potential
Transmembrane82 – 10221Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane228 – 24821Helical; Potential
Transmembrane305 – 32521Helical; Potential
Transmembrane342 – 36221Helical; Potential
Transmembrane399 – 41921Helical; Potential
Compositional bias59 – 635Poly-Ala

Natural variations

Natural variant5651P → S.
Corresponds to variant rs847079 [ dbSNP | Ensembl ].
VAR_050919

Sequences

Sequence LengthMass (Da)Tools
Q9BR26 [UniParc].

Last modified July 1, 2008. Version 2.
Checksum: 3F2F24D0137F859E

FASTA56661,579
        10         20         30         40         50         60 
MPGHPGAAEQ LVKTGWRSWH LGFWKALAPL QAAWDAFSQP VPASCGQLLT QLLLCASLAA 

        70         80         90        100        110        120 
AAAGLVYHWL ASLLLYPPGP SAMVATVCGL LVFLSLGLVP PVRCLFALSV PTLGMEQGRR 

       130        140        150        160        170        180 
LLLSYSTATL AIAVVPNVLA NVGAAGQVLR CVTEGSLESL LNTTHQLHAA SRALGPTGQA 

       190        200        210        220        230        240 
GSRGLTFEAQ DNGSAFYLHM LRVTQQVLED FSGLESLARA AALGTQRVVT GLFMLGLLVE 

       250        260        270        280        290        300 
SAWYLHCYLT DLRFDNIYAT QQLTQRLAQA QATHLLAPPP TWLLQAAQLR LSQEELLSCL 

       310        320        330        340        350        360 
LRLGLLALLL VATAVAVATD HVAFLLAQAT VDWAQKLPTV PITLTVKYDV AYTVLGFIPF 

       370        380        390        400        410        420 
LFNQLAPESP FLSVHSSYQW ELRLTSARCP LLPARRPRAA APLAAGALQL LAGSTVLLEA 

       430        440        450        460        470        480 
YARRLRHAIA ASFFTAQEAR RVRHLHARLQ RRHDRHQGQQ LPLGDPSCVP TPRPACKPPA 

       490        500        510        520        530        540 
WIDYRLDALR TESSEGEGKE LWSCRDLSCN LGPVPPPCVT LGKSLHLSEP RFLHLHNDSI 

       550        560 
FTIDVTYFPR RDVVRMEGNT GHDRPG

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed: 11780052] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL034424 Genomic DNA. Translation: CAC36102.2.
IPIIPI00552151.
RefSeqNP_542452.1. NM_080721.1.
UniGeneHs.526636.

3D structure databases

ProteinModelPortalQ9BR26.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9BR26.

Polymorphism databases

DMDM193806176.

Proteomic databases

PRIDEQ9BR26.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000279028; ENSP00000279028; ENSG00000149635.
GeneID128506.
KEGGhsa:128506.

Organism-specific databases

CTD128506.
GeneCardsGC20M045169.
HGNCHGNC:16116. C20orf123.
HPAHPA031116.
neXtProtNX_Q9BR26.
PharmGKBPA25664.
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG07058.
GeneTreeENSGT00530000064296.
HOGENOMHBG506206.
HOVERGENHBG107776.
InParanoidQ9BR26.
OMAWYLHRYL.
OrthoDBEOG4PC9SP.

Gene expression databases

ArrayExpressQ9BR26.
BgeeQ9BR26.
CleanExHS_C20orf123.
GenevestigatorQ9BR26.

Family and domain databases

InterProIPR012858. DC_STAMP-like.
[Graphical view]
PfamPF07782. DC_STAMP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio82378.

Entry information

Entry nameCT123_HUMAN
AccessionPrimary (citable) accession number: Q9BR26
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents