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Q9BR11 (ZSWM1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger SWIM domain-containing protein 1
Gene names
Name:ZSWIM1
Synonyms:C20orf162
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SWIM-type zinc finger.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 485485Zinc finger SWIM domain-containing protein 1
PRO_0000223095

Regions

Zinc finger363 – 40543SWIM-type

Natural variations

Natural variant1011R → Q.
Corresponds to variant rs3746500 [ dbSNP | Ensembl ].
VAR_020445

Sequences

Sequence LengthMass (Da)Tools
Q9BR11 [UniParc].

Last modified August 30, 2005. Version 2.
Checksum: F7447E98EFC6FD6E

FASTA48555,071
        10         20         30         40         50         60 
MLERLKAPWS AALQRKYFDL GIWTAPISPM ALTMLNGLLI KDSSPPMLLH QVNKTAQLDT 

        70         80         90        100        110        120 
FNYQSCFMQS VFDHFPEILF IHRTYNPRGK VLYTFLVDGP RVQLEGHLAR AVYFAIPAKE 

       130        140        150        160        170        180 
DTEGLAQMFQ VFKKFNPAWE RVCTILVDPH FLPLPILAME FPTAEVLLSA FHICKFLQAK 

       190        200        210        220        230        240 
FYQLSLERPV ERLLLTSLQS TMCSATAGNL RKLYTLLSNC IPPAKLPELH SHWLLNDRIW 

       250        260        270        280        290        300 
LAHRWRSRAE SSHYFQSLEV TTHILSQFFG TTPSEKQGMA SLFRYMQQNS ADKANFNQGL 

       310        320        330        340        350        360 
CAQNNHAPSD TIPESPKLEQ LVESHIQHSL NAICTGPAAQ LCLGELAVVQ KSTHLIGSGS 

       370        380        390        400        410        420 
EKMNIQILED THKVQPQPPA SCSCYFNQAF HLPCRHILAM LSARRQVLQP DMLPAQWTAG 

       430        440        450        460        470        480 
CATSLDSILG SKWSETLDKH LAVTHLTEEV GQLLQHCTKE EFERRYSTLR ELADSWIGPY 


EQVQL 

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Colon.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL008726 Genomic DNA. Translation: CAI20247.1.
BC001672 mRNA. Translation: AAH01672.3.
BC080525 mRNA. Translation: AAH80525.2.
RefSeqNP_542170.3. NM_080603.4.
XP_005260667.1. XM_005260610.2.
XP_005260668.1. XM_005260611.2.
UniGeneHs.517075.

3D structure databases

ProteinModelPortalQ9BR11.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid124678. 2 interactions.
IntActQ9BR11. 3 interactions.

PTM databases

PhosphoSiteQ9BR11.

Polymorphism databases

DMDM73920980.

Proteomic databases

PaxDbQ9BR11.
PRIDEQ9BR11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000372520; ENSP00000361598; ENSG00000168612.
ENST00000372523; ENSP00000361601; ENSG00000168612.
GeneID90204.
KEGGhsa:90204.
UCSCuc010ghi.3. human.

Organism-specific databases

CTD90204.
GeneCardsGC20P044509.
HGNCHGNC:16155. ZSWIM1.
HPAHPA041147.
HPA046751.
neXtProtNX_Q9BR11.
PharmGKBPA25704.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG45779.
HOGENOMHOG000231003.
HOVERGENHBG099855.
InParanoidQ9BR11.
OMAIWLAHRW.
OrthoDBEOG7327NB.
PhylomeDBQ9BR11.
TreeFamTF335703.

Enzyme and pathway databases

SignaLinkQ9BR11.

Gene expression databases

ArrayExpressQ9BR11.
BgeeQ9BR11.
CleanExHS_ZSWIM1.
GenevestigatorQ9BR11.

Family and domain databases

InterProIPR007527. Znf_SWIM.
[Graphical view]
PfamPF04434. SWIM. 1 hit.
[Graphical view]
PROSITEPS50966. ZF_SWIM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSZSWIM1. human.
GenomeRNAi90204.
NextBio76599.
PROQ9BR11.

Entry information

Entry nameZSWM1_HUMAN
AccessionPrimary (citable) accession number: Q9BR11
Secondary accession number(s): Q5JZH2, Q9BR12, Q9BV30
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM