Q9BR11 (ZSWM1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc finger SWIM domain-containing protein 1

Gene names

Name:	ZSWIM1
Synonyms:	C20orf162

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SWIM-type zinc finger.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Domain	Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 485	485	Zinc finger SWIM domain-containing protein 1		PRO_0000223095
Regions
	Zinc finger	363 – 405	43	SWIM-type
Natural variations
	Natural variant	101	1	R → Q. Corresponds to variant rs3746500 [ dbSNP | Ensembl ].		VAR_020445

Sequences

	Sequence		Length	Mass (Da)
	Q9BR11 [UniParc]. Last modified August 30, 2005. Version 2. Checksum: F7447E98EFC6FD6E	FASTA	485	55,071
	10 20 30 40 50 60 MLERLKAPWS AALQRKYFDL GIWTAPISPM ALTMLNGLLI KDSSPPMLLH QVNKTAQLDT 70 80 90 100 110 120 FNYQSCFMQS VFDHFPEILF IHRTYNPRGK VLYTFLVDGP RVQLEGHLAR AVYFAIPAKE 130 140 150 160 170 180 DTEGLAQMFQ VFKKFNPAWE RVCTILVDPH FLPLPILAME FPTAEVLLSA FHICKFLQAK 190 200 210 220 230 240 FYQLSLERPV ERLLLTSLQS TMCSATAGNL RKLYTLLSNC IPPAKLPELH SHWLLNDRIW 250 260 270 280 290 300 LAHRWRSRAE SSHYFQSLEV TTHILSQFFG TTPSEKQGMA SLFRYMQQNS ADKANFNQGL 310 320 330 340 350 360 CAQNNHAPSD TIPESPKLEQ LVESHIQHSL NAICTGPAAQ LCLGELAVVQ KSTHLIGSGS 370 380 390 400 410 420 EKMNIQILED THKVQPQPPA SCSCYFNQAF HLPCRHILAM LSARRQVLQP DMLPAQWTAG 430 440 450 460 470 480 CATSLDSILG SKWSETLDKH LAVTHLTEEV GQLLQHCTKE EFERRYSTLR ELADSWIGPY EQVQL

References

[1]

"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL008726 Genomic DNA. Translation: CAI20247.1. BC001672 mRNA. Translation: AAH01672.3. BC080525 mRNA. Translation: AAH80525.2.
IPI	IPI00094590.
RefSeq	NP_542170.3. NM_080603.4.
UniGene	Hs.517075.
3D structure databases
ProteinModelPortal	Q9BR11.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BR11. 3 interactions.
PTM databases
PhosphoSite	Q9BR11.
Polymorphism databases
DMDM	73920980.
Proteomic databases
PaxDb	Q9BR11.
PRIDE	Q9BR11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000372520; ENSP00000361598; ENSG00000168612. ENST00000372523; ENSP00000361601; ENSG00000168612.
GeneID	90204.
KEGG	hsa:90204.
UCSC	uc010ghi.3. human.
Organism-specific databases
CTD	90204.
GeneCards	GC20P044509.
HGNC	HGNC:16155. ZSWIM1.
HPA	HPA041147. HPA046751.
neXtProt	NX_Q9BR11.
PharmGKB	PA25704.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG45779.
HOGENOM	HOG000231003.
HOVERGEN	HBG099855.
InParanoid	Q9BR11.
OMA	DRIWLAH.
OrthoDB	EOG4QFWD0.
Gene expression databases
ArrayExpress	Q9BR11.
Bgee	Q9BR11.
CleanEx	HS_ZSWIM1.
Genevestigator	Q9BR11.
GermOnline	ENSG00000168612. Homo sapiens.
Family and domain databases
InterPro	IPR007527. Znf_SWIM. [Graphical view]
Pfam	PF04434. SWIM. 1 hit. [Graphical view]
PROSITE	PS50966. ZF_SWIM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ZSWIM1. human.
GenomeRNAi	90204.
NextBio	76599.

Entry information

Entry name

ZSWM1_HUMAN

Accession

Primary (citable) accession number: Q9BR11
Secondary accession number(s): Q5JZH2, Q9BR12, Q9BV30

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	August 30, 2005
Last modified:	April 3, 2013
This is version 82 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.