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Protein
Submitted name:

6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase

Gene

PFKFB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 6-phosphofructo-2-kinase activity Source: UniProtKB-EC
  2. ATP binding Source: InterPro

GO - Biological processi

  1. fructose 2,6-bisphosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
6-phosphofructo-2-kinase/ fructose-2,6-bisphosphataseImported (EC:2.7.1.105Imported)
Gene namesi
Name:PFKFB3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiQ9BQU2.
ExpressionAtlasiQ9BQU2. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR003094. 6Pfruct_kin.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9BQU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IYLNVESVCT HRERSEDAKK GPNPLMRRNS VTPLASPEPT KKPRINSFEE
60 70 80 90
HVASTSAALP SCLPPEVPTQ LPGQPLLGQA CLRTVCHIFS KFSPY
Length:95
Mass (Da):10,469
Last modified:June 1, 2001 - v1
Checksum:i98A9E8C410909E41
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272439 mRNA. Translation: CAC34793.1.
UniGeneiHs.195471.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272439 mRNA. Translation: CAC34793.1.
UniGeneiHs.195471.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiPFKFB3. human.

Gene expression databases

BgeeiQ9BQU2.
ExpressionAtlasiQ9BQU2. baseline and differential.

Family and domain databases

InterProiIPR003094. 6Pfruct_kin.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain."
    Kessler R., Eschrich K.
    Brain Res. Mol. Brain Res. 87:190-195(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CaucasianImported.
    Tissue: BrainImported.
  2. "Alternative splicing of ubiquitous 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase in human brain."
    Kessler R., Eschrich K.
    FEBS Lett. 0:0-0(1)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CaucasianImported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ9BQU2_HUMAN
AccessioniPrimary (citable) accession number: Q9BQU2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 26, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.