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Protein
Submitted name:

6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase

Gene

PFKFB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
6-phosphofructo-2-kinase/ fructose-2,6-bisphosphataseImported (EC:2.7.1.105Imported)
Gene namesi
Name:PFKFB3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ9BQU2.

Expressioni

Gene expression databases

BgeeiQ9BQU2.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369100.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0234. Eukaryota.
COG0406. LUCA.

Family and domain databases

InterProiIPR003094. 6Pfruct_kin.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9BQU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IYLNVESVCT HRERSEDAKK GPNPLMRRNS VTPLASPEPT KKPRINSFEE
60 70 80 90
HVASTSAALP SCLPPEVPTQ LPGQPLLGQA CLRTVCHIFS KFSPY
Length:95
Mass (Da):10,469
Last modified:June 1, 2001 - v1
Checksum:i98A9E8C410909E41
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272439 mRNA. Translation: CAC34793.1.
UniGeneiHs.195471.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272439 mRNA. Translation: CAC34793.1.
UniGeneiHs.195471.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369100.

Proteomic databases

PaxDbiQ9BQU2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0234. Eukaryota.
COG0406. LUCA.

Miscellaneous databases

ChiTaRSiPFKFB3. human.

Gene expression databases

BgeeiQ9BQU2.

Family and domain databases

InterProiIPR003094. 6Pfruct_kin.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain."
    Kessler R., Eschrich K.
    Brain Res. Mol. Brain Res. 87:190-195(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CaucasianImported.
    Tissue: BrainImported.
  2. "Alternative splicing of ubiquitous 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase in human brain."
    Kessler R., Eschrich K.
    FEBS Lett. 0:0-0(0)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CaucasianImported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ9BQU2_HUMAN
AccessioniPrimary (citable) accession number: Q9BQU2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: March 16, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.