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Q9BQF6

- SENP7_HUMAN

UniProt

Q9BQF6 - SENP7_HUMAN

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Protein

Sentrin-specific protease 7

Gene
SENP7, KIAA1707, SSP2, SUSP2
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.1 Publication

Catalytic activityi

Hydrolysis of the alpha-linked peptide bond in the sequence Gly-Gly-|-Ala-Thr-Tyr at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptide, Smt3, leading to the mature form of the protein. A second reaction involves the cleavage of an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei860 – 8601 By similarity
Active sitei992 – 9921 By similarity

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
  2. protein binding Source: IntAct
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Keywords - Biological processi

Ubl conjugation pathway

Protein family/group databases

MEROPSiC48.009.

Names & Taxonomyi

Protein namesi
Recommended name:
Sentrin-specific protease 7 (EC:3.4.22.68)
Alternative name(s):
SUMO-1-specific protease 2
Sentrin/SUMO-specific protease SENP7
Gene namesi
Name:SENP7
Synonyms:KIAA1707, SSP2, SUSP2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:30402. SENP7.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: LIFEdb
  2. nucleus Source: LIFEdb
Complete GO annotation...

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi775 – 7751F → W: Slightly increased deconjugation activity. 1 Publication
Mutagenesisi779 – 7791V → E: Reduces deconjugation activity. 1 Publication

Organism-specific databases

PharmGKBiPA134925171.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10501050Sentrin-specific protease 7PRO_0000101726Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei25 – 251Phosphoserine1 Publication
Modified residuei443 – 4431Phosphoserine1 Publication
Modified residuei444 – 4441Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9BQF6.
PaxDbiQ9BQF6.
PRIDEiQ9BQF6.

PTM databases

PhosphoSiteiQ9BQF6.

Expressioni

Gene expression databases

ArrayExpressiQ9BQF6.
BgeeiQ9BQF6.
CleanExiHS_SENP7.
GenevestigatoriQ9BQF6.

Organism-specific databases

HPAiHPA027259.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CBX5P459732EBI-766251,EBI-78219
TRIM28Q132632EBI-766251,EBI-78139

Protein-protein interaction databases

BioGridi121491. 2 interactions.
IntActiQ9BQF6. 3 interactions.
MINTiMINT-4717645.
STRINGi9606.ENSP00000377655.

Structurei

Secondary structure

1
1050
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi747 – 7526
Beta strandi756 – 7583
Beta strandi760 – 7634
Helixi764 – 7685
Helixi778 – 79114
Helixi795 – 7995
Beta strandi801 – 8033
Helixi807 – 8126
Helixi828 – 8336
Helixi837 – 8404
Helixi845 – 8473
Beta strandi849 – 8579
Beta strandi860 – 8678
Beta strandi933 – 9386
Helixi946 – 96520
Turni973 – 9753
Helixi992 – 100514
Helixi1023 – 10275
Helixi1029 – 104618

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3EAYX-ray2.40A728-1050[»]
ProteinModelPortaliQ9BQF6.
SMRiQ9BQF6. Positions 744-1047.

Miscellaneous databases

EvolutionaryTraceiQ9BQF6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni760 – 1050291ProteaseAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C48 family.

Phylogenomic databases

eggNOGiCOG5160.
HOVERGENiHBG079864.
KOiK08596.
OMAiFIFLELH.
OrthoDBiEOG780RMX.
PhylomeDBiQ9BQF6.
TreeFamiTF350136.

Family and domain databases

InterProiIPR003653. Peptidase_C48.
[Graphical view]
PfamiPF02902. Peptidase_C48. 1 hit.
[Graphical view]
PROSITEiPS50600. ULP_PROTEASE. 1 hit.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. Align

Note: Experimental confirmation may be lacking for some isoforms.

Isoform 1 (identifier: Q9BQF6-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MDKRKLGRRP SSSEIITEGK RKKSSSDLSE IRKMLNAKPE DVHVQSPLSK     50
FRSSERWTLP LQWERSLRNK VISLDHKNKK HIRGCPVTSK SSPERQLKVM 100
LTNVLWTDLG RKFRKTLPRN DANLCDANKV QSDSLPSTSV DSLETCQKLE 150
PLRQSLNLSE RIPRVILTNV LGTELGRKYI RTPPVTEGSL SDTDNLQSEQ 200
LSSSSDGSLE SYQNLNPHKS CYLSERGSQR SKTVDDNSAK QTAHNKEKRR 250
KDDGISLLIS DTQPEDLNSG SRGCDHLEQE SRNKDVKYSD SKVELTLISR 300
KTKRRLRNNL PDSQYCTSLD KSTEQTKKQE DDSTISTEFE KPSENYHQDP 350
KLPEEITTKP TKSDFTKLSS LNSQELTLSN ATKSASAGST TETVENSNSI 400
DIVGISSLVE KDENELNTIE KPILRGHNEG NQSLISAEPI VVSSDEEGPV 450
EHKSSEILKL QSKQDRETTN ENESTSESAL LELPLITCES VQMSSELCPY 500
NPVMENISSI MPSNEMDLQL DFIFTSVYIG KIKGASKGCV TITKKYIKIP 550
FQVSLNEISL LVDTTHLKRF GLWKSKDDNH SKRSHAILFF WVSSDYLQEI 600
QTQLEHSVLS QQSKSSEFIF LELHNPVSQR EELKLKDIMT EISIISGELE 650
LSYPLSWVQA FPLFQNLSSK ESSFIHYYCV STCSFPAGVA VAEEMKLKSV 700
SQPSNTDAAK PTYTFLQKQS SGCYSLSITS NPDEEWREVR HTGLVQKLIV 750
YPPPPTKGGL GVTNEDLECL EEGEFLNDVI IDFYLKYLIL EKASDELVER 800
SHIFSSFFYK CLTRKENNLT EDNPNLSMAQ RRHKRVRTWT RHINIFNKDY 850
IFVPVNESSH WYLAVICFPW LEEAVYEDFP QTVSQQSQAQ QSQNDNKTID 900
NDLRTTSTLS LSAEDSQSTE SNMSVPKKMC KRPCILILDS LKAASVQNTV 950
QNLREYLEVE WEVKLKTHRQ FSKTNMVDLC PKVPKQDNSS DCGVYLLQYV 1000
ESFFKDPIVN FELPIHLEKW FPRHVIKTKR EDIRELILKL HLQQQKGSSS 1050
Length:1,050
Mass (Da):119,658
Last modified:July 13, 2010 - v4
Checksum:iCB455A0B22709052
GO
Isoform 2 (identifier: Q9BQF6-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-33: Missing.

Show »
Length:1,017
Mass (Da):115,871
Checksum:iF0C8278BCC440AA8
GO
Isoform 3 (identifier: Q9BQF6-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-812: Missing.
     813-827: TRKENNLTEDNPNLS → MKKFLYIKSVFHTLR

Show »
Length:238
Mass (Da):28,124
Checksum:i9661C4384D6A30D7
GO
Isoform 4 (identifier: Q9BQF6-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-33: Missing.
     95-225: Missing.

Show »
Length:886
Mass (Da):101,195
Checksum:iB03DA49EB00C0007
GO
Isoform 5 (identifier: Q9BQF6-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     95-160: Missing.

Show »
Length:984
Mass (Da):112,159
Checksum:iE5EBB74CAC3E39C5
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti79 – 791K → Q.
Corresponds to variant rs6809436 [ dbSNP | Ensembl ].
VAR_029651
Natural varianti612 – 6121Q → H.1 Publication
Corresponds to variant rs2433031 [ dbSNP | Ensembl ].
VAR_029652

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 812812Missing in isoform 3. VSP_039498Add
BLAST
Alternative sequencei1 – 3333Missing in isoform 2 and isoform 4. VSP_039499Add
BLAST
Alternative sequencei95 – 225131Missing in isoform 4. VSP_039501Add
BLAST
Alternative sequencei95 – 16066Missing in isoform 5. VSP_039500Add
BLAST
Alternative sequencei813 – 82715TRKEN…NPNLS → MKKFLYIKSVFHTLR in isoform 3. VSP_039502Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti90 – 901K → R in CAB66534. 1 Publication
Sequence conflicti341 – 3411K → R in CAB66534. 1 Publication
Sequence conflicti396 – 3961N → Y in CAB66534. 1 Publication
Sequence conflicti785 – 7851L → H in AAL25651. 1 Publication
Sequence conflicti894 – 8941N → S in CAB66534. 1 Publication
Sequence conflicti947 – 9471Q → R in CAB66534. 1 Publication
Sequence conflicti1006 – 10061D → N in AAL25651. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF199458 mRNA. Translation: AAL25651.1.
AF217504 mRNA. Translation: AAG09703.1.
AL136599 mRNA. Translation: CAB66534.1.
BX537943 mRNA. Translation: CAD97911.1.
AC068764 Genomic DNA. No translation available.
AC073861 Genomic DNA. No translation available.
AC110994 Genomic DNA. No translation available.
BC129988 mRNA. Translation: AAI29989.1.
AB051494 mRNA. Translation: BAB21798.1.
CCDSiCCDS2941.2. [Q9BQF6-1]
CCDS63704.1. [Q9BQF6-4]
CCDS63705.1. [Q9BQF6-2]
CCDS63706.1. [Q9BQF6-5]
RefSeqiNP_001070671.1. NM_001077203.2.
NP_001269730.1. NM_001282801.1. [Q9BQF6-5]
NP_001269731.1. NM_001282802.1. [Q9BQF6-2]
NP_001269732.1. NM_001282803.1. [Q9BQF6-4]
NP_001269733.1. NM_001282804.1.
NP_065705.3. NM_020654.4. [Q9BQF6-1]
UniGeneiHs.529551.

Genome annotation databases

EnsembliENST00000314261; ENSP00000313624; ENSG00000138468. [Q9BQF6-5]
ENST00000348610; ENSP00000342159; ENSG00000138468. [Q9BQF6-2]
ENST00000358203; ENSP00000350936; ENSG00000138468. [Q9BQF6-4]
ENST00000394085; ENSP00000377647; ENSG00000138468. [Q9BQF6-3]
ENST00000394091; ENSP00000377651; ENSG00000138468. [Q9BQF6-4]
ENST00000394095; ENSP00000377655; ENSG00000138468. [Q9BQF6-1]
GeneIDi57337.
KEGGihsa:57337.
UCSCiuc003dus.3. human. [Q9BQF6-3]
uc003dut.3. human. [Q9BQF6-1]
uc003duw.3. human. [Q9BQF6-5]
uc003dux.3. human. [Q9BQF6-4]

Polymorphism databases

DMDMi300669717.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF199458 mRNA. Translation: AAL25651.1 .
AF217504 mRNA. Translation: AAG09703.1 .
AL136599 mRNA. Translation: CAB66534.1 .
BX537943 mRNA. Translation: CAD97911.1 .
AC068764 Genomic DNA. No translation available.
AC073861 Genomic DNA. No translation available.
AC110994 Genomic DNA. No translation available.
BC129988 mRNA. Translation: AAI29989.1 .
AB051494 mRNA. Translation: BAB21798.1 .
CCDSi CCDS2941.2. [Q9BQF6-1 ]
CCDS63704.1. [Q9BQF6-4 ]
CCDS63705.1. [Q9BQF6-2 ]
CCDS63706.1. [Q9BQF6-5 ]
RefSeqi NP_001070671.1. NM_001077203.2.
NP_001269730.1. NM_001282801.1. [Q9BQF6-5 ]
NP_001269731.1. NM_001282802.1. [Q9BQF6-2 ]
NP_001269732.1. NM_001282803.1. [Q9BQF6-4 ]
NP_001269733.1. NM_001282804.1.
NP_065705.3. NM_020654.4. [Q9BQF6-1 ]
UniGenei Hs.529551.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3EAY X-ray 2.40 A 728-1050 [» ]
ProteinModelPortali Q9BQF6.
SMRi Q9BQF6. Positions 744-1047.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121491. 2 interactions.
IntActi Q9BQF6. 3 interactions.
MINTi MINT-4717645.
STRINGi 9606.ENSP00000377655.

Chemistry

BindingDBi Q9BQF6.
ChEMBLi CHEMBL1741213.

Protein family/group databases

MEROPSi C48.009.

PTM databases

PhosphoSitei Q9BQF6.

Polymorphism databases

DMDMi 300669717.

Proteomic databases

MaxQBi Q9BQF6.
PaxDbi Q9BQF6.
PRIDEi Q9BQF6.

Protocols and materials databases

DNASUi 57337.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000314261 ; ENSP00000313624 ; ENSG00000138468 . [Q9BQF6-5 ]
ENST00000348610 ; ENSP00000342159 ; ENSG00000138468 . [Q9BQF6-2 ]
ENST00000358203 ; ENSP00000350936 ; ENSG00000138468 . [Q9BQF6-4 ]
ENST00000394085 ; ENSP00000377647 ; ENSG00000138468 . [Q9BQF6-3 ]
ENST00000394091 ; ENSP00000377651 ; ENSG00000138468 . [Q9BQF6-4 ]
ENST00000394095 ; ENSP00000377655 ; ENSG00000138468 . [Q9BQF6-1 ]
GeneIDi 57337.
KEGGi hsa:57337.
UCSCi uc003dus.3. human. [Q9BQF6-3 ]
uc003dut.3. human. [Q9BQF6-1 ]
uc003duw.3. human. [Q9BQF6-5 ]
uc003dux.3. human. [Q9BQF6-4 ]

Organism-specific databases

CTDi 57337.
GeneCardsi GC03M101043.
H-InvDB HIX0003507.
HGNCi HGNC:30402. SENP7.
HPAi HPA027259.
MIMi 612846. gene.
neXtProti NX_Q9BQF6.
PharmGKBi PA134925171.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5160.
HOVERGENi HBG079864.
KOi K08596.
OMAi FIFLELH.
OrthoDBi EOG780RMX.
PhylomeDBi Q9BQF6.
TreeFami TF350136.

Miscellaneous databases

EvolutionaryTracei Q9BQF6.
GeneWikii SENP7.
GenomeRNAii 57337.
NextBioi 63454.
PROi Q9BQF6.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9BQF6.
Bgeei Q9BQF6.
CleanExi HS_SENP7.
Genevestigatori Q9BQF6.

Family and domain databases

InterProi IPR003653. Peptidase_C48.
[Graphical view ]
Pfami PF02902. Peptidase_C48. 1 hit.
[Graphical view ]
PROSITEi PS50600. ULP_PROTEASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Choi S.J., Jeon Y.-J., Kim K.I., Nishimori S., Suzuki T., Uchida S., Shimbara N., Tanaka K., Chung C.H.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
  2. "SENP7, a novel human sentrin-specific protease."
    Gong L., Yeh E.T.H.
    Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    Tissue: Placenta.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5).
    Tissue: Brain.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Fetal kidney.
  5. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  7. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O.
    DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 295-1050, VARIANT HIS-612.
    Tissue: Brain.
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25; SER-443 AND SER-444, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  10. "Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7."
    Lima C.D., Reverter D.
    J. Biol. Chem. 283:32045-32055(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 728-1050, FUNCTION, MUTAGENESIS OF PHE-775 AND VAL-779.

Entry informationi

Entry nameiSENP7_HUMAN
AccessioniPrimary (citable) accession number: Q9BQF6
Secondary accession number(s): A1L3A5
, A8MW39, B7WNW8, Q7Z3F4, Q96PS5, Q9C0F6, Q9HBT5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 108 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Peptidase families
    Classification of peptidase families and list of entries
  7. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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