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Protein

LBH domain-containing protein 1

Gene

LBHD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
LBH domain-containing protein 1Imported
Gene namesi
Name:LBHD1Imported
Synonyms:C11orf48Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:28351. LBHD1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672293.

Polymorphism and mutation databases

BioMutaiC11orf48.
DMDMi145558878.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289LBH domain-containing protein 1PRO_0000284493Add
BLAST

Proteomic databases

MaxQBiQ9BQE6.
PeptideAtlasiQ9BQE6.
PRIDEiQ9BQE6.

PTM databases

iPTMnetiQ9BQE6.
PhosphoSiteiQ9BQE6.

Expressioni

Tissue specificityi

Expressed in bladder cancer tissues (at protein level).1 Publication

Gene expression databases

BgeeiENSG00000162194.
CleanExiHS_C11orf48.
ExpressionAtlasiQ9BQE6. baseline and differential.
GenevisibleiQ9BQE6. HS.

Organism-specific databases

HPAiHPA012127.
HPA023592.

Interactioni

Protein-protein interaction databases

BioGridi122530. 8 interactions.
IntActiQ9BQE6. 1 interaction.
MINTiMINT-5003475.

Structurei

3D structure databases

ProteinModelPortaliQ9BQE6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00400000022873.
HOGENOMiHOG000070171.
HOVERGENiHBG107701.
InParanoidiQ9BQE6.
OrthoDBiEOG091G0MJ7.
PhylomeDBiQ9BQE6.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9BQE6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MALVPGRSKE DGLWTRNSPG SSQHPESPRL PNPLWDRGKI GKVEGHQHIQ
60 70 80 90 100
VSTSSACVWQ LAYPPVWPNL PAVPIQDFSQ KSHLPSIVVE SSEVNEESGD
110 120 130 140 150
LHLPHEELLL LTDGEEEDAE AFFQDQSEEP GWAWSPQDPR SPLRTFNAGL
160 170 180 190 200
SWGQDQDEED ACWILEDTAC LEATNHCPFW DSTGSRVCRS GFVEYSHLLP
210 220 230 240 250
PNSFEGAEEE AVQTPAGVES GAASEAPGGR GCDRPRADHA APPQEAGVQC
260 270 280
TCQHYTVREE AQKTPPADPA CPEREDSHGS GSPFKASQD
Note: No experimental confirmation available.
Length:289
Mass (Da):31,565
Last modified:April 17, 2007 - v3
Checksum:iDAE62DC699180B47
GO
Isoform 2 (identifier: Q9BQE6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     51-76: Missing.

Note: No experimental confirmation available.
Show »
Length:263
Mass (Da):28,759
Checksum:iD770AE303F378012
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei51 – 7626Missing in isoform 2. 1 PublicationVSP_024545Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055736 mRNA. No translation available.
BC001434 mRNA. Translation: AAH01434.2.
CCDSiCCDS8028.1. [Q9BQE6-2]
RefSeqiNP_077004.2. NM_024099.3. [Q9BQE6-2]
UniGeneiHs.9061.

Genome annotation databases

EnsembliENST00000354588; ENSP00000346600; ENSG00000162194. [Q9BQE6-2]
ENST00000431002; ENSP00000416856; ENSG00000162194. [Q9BQE6-1]
ENST00000532208; ENSP00000436848; ENSG00000162194. [Q9BQE6-2]
GeneIDi79081.
KEGGihsa:79081.
UCSCiuc001nuf.3. human. [Q9BQE6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055736 mRNA. No translation available.
BC001434 mRNA. Translation: AAH01434.2.
CCDSiCCDS8028.1. [Q9BQE6-2]
RefSeqiNP_077004.2. NM_024099.3. [Q9BQE6-2]
UniGeneiHs.9061.

3D structure databases

ProteinModelPortaliQ9BQE6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122530. 8 interactions.
IntActiQ9BQE6. 1 interaction.
MINTiMINT-5003475.

PTM databases

iPTMnetiQ9BQE6.
PhosphoSiteiQ9BQE6.

Polymorphism and mutation databases

BioMutaiC11orf48.
DMDMi145558878.

Proteomic databases

MaxQBiQ9BQE6.
PeptideAtlasiQ9BQE6.
PRIDEiQ9BQE6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000354588; ENSP00000346600; ENSG00000162194. [Q9BQE6-2]
ENST00000431002; ENSP00000416856; ENSG00000162194. [Q9BQE6-1]
ENST00000532208; ENSP00000436848; ENSG00000162194. [Q9BQE6-2]
GeneIDi79081.
KEGGihsa:79081.
UCSCiuc001nuf.3. human. [Q9BQE6-1]

Organism-specific databases

CTDi79081.
GeneCardsiLBHD1.
H-InvDBHIX0201619.
HGNCiHGNC:28351. LBHD1.
HPAiHPA012127.
HPA023592.
neXtProtiNX_Q9BQE6.
PharmGKBiPA142672293.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00400000022873.
HOGENOMiHOG000070171.
HOVERGENiHBG107701.
InParanoidiQ9BQE6.
OrthoDBiEOG091G0MJ7.
PhylomeDBiQ9BQE6.

Miscellaneous databases

ChiTaRSiC11orf48. human.
GenomeRNAii79081.
PROiQ9BQE6.

Gene expression databases

BgeeiENSG00000162194.
CleanExiHS_C11orf48.
ExpressionAtlasiQ9BQE6. baseline and differential.
GenevisibleiQ9BQE6. HS.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiLBHD1_HUMAN
AccessioniPrimary (citable) accession number: Q9BQE6
Secondary accession number(s): Q96NA4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: September 7, 2016
This is version 93 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.