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Protein

Putative pro-MCH-like protein 2

Gene

PMCHL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:ENSG00000169040-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pro-MCH-like protein 2
Alternative name(s):
Pro-melanin-concentrating hormone-like protein 2
Gene namesi
Name:PMCHL2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:9111. PMCHL2.

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi71153828.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001582721 – 86Putative pro-MCH-like protein 2Add BLAST86

Proteomic databases

PRIDEiQ9BQD1.

Expressioni

Tissue specificityi

Expressed in testis but not in brain.

Developmental stagei

Not expressed during brain development.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ9BQD1.
SMRiQ9BQD1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni31 – 49NGE-likeAdd BLAST19
Regioni52 – 64NEI-likeAdd BLAST13
Regioni68 – 86Melanin-concentrating hormone-likeAdd BLAST19

Sequence similaritiesi

Phylogenomic databases

HOVERGENiHBG052428.
InParanoidiQ9BQD1.
PhylomeDBiQ9BQD1.

Family and domain databases

InterProiIPR005456. Prepro-melanin_conc_hormone.
[Graphical view]
PANTHERiPTHR12091. PTHR12091. 1 hit.
PfamiPF05824. Pro-MCH. 1 hit.
[Graphical view]
PRINTSiPR01641. PROMCHFAMILY.

Sequencei

Sequence statusi: Complete.

Q9BQD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSQKTKKKH NFLNHGLSLN LVIKPYLALE GSVAFPAENG VQDTESTLEK
60 70 80
RETGDEENSA KFPIGRRDFD TLRCMLGRVY QRCWQV
Length:86
Mass (Da):9,856
Last modified:June 1, 2001 - v1
Checksum:i1C8D69B786B47471
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY008413 mRNA. Translation: AAK31297.1.
AY008412 mRNA. Translation: AAK31296.1.
AY028320 Genomic DNA. Translation: AAK31290.1.
UniGeneiHs.742169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY008413 mRNA. Translation: AAK31297.1.
AY008412 mRNA. Translation: AAK31296.1.
AY028320 Genomic DNA. Translation: AAK31290.1.
UniGeneiHs.742169.

3D structure databases

ProteinModelPortaliQ9BQD1.
SMRiQ9BQD1.
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

DMDMi71153828.

Proteomic databases

PRIDEiQ9BQD1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiPMCHL2.
HGNCiHGNC:9111. PMCHL2.
MIMi176794. gene.
neXtProtiNX_Q9BQD1.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG052428.
InParanoidiQ9BQD1.
PhylomeDBiQ9BQD1.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000169040-MONOMER.

Miscellaneous databases

PROiQ9BQD1.
SOURCEiSearch...

Family and domain databases

InterProiIPR005456. Prepro-melanin_conc_hormone.
[Graphical view]
PANTHERiPTHR12091. PTHR12091. 1 hit.
PfamiPF05824. Pro-MCH. 1 hit.
[Graphical view]
PRINTSiPR01641. PROMCHFAMILY.
ProtoNetiSearch...

Entry informationi

Entry nameiMCHL2_HUMAN
AccessioniPrimary (citable) accession number: Q9BQD1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.