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Protein

Small integral membrane protein 7

Gene

SMIM7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 7
Gene namesi
Name:SMIM7
Synonyms:C19orf42
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000214046.8
HGNCiHGNC:28419 SMIM7
neXtProtiNX_Q9BQ49

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini18 – 53ExtracellularSequence analysisAdd BLAST36
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Topological domaini75CytoplasmicSequence analysis1

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000214046
PharmGKBiPA144596475

Polymorphism and mutation databases

BioMutaiSMIM7
DMDMi193806332

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000028404718 – 75Small integral membrane protein 7Add BLAST58

Proteomic databases

EPDiQ9BQ49
MaxQBiQ9BQ49
PaxDbiQ9BQ49
PeptideAtlasiQ9BQ49
PRIDEiQ9BQ49
TopDownProteomicsiQ9BQ49

PTM databases

iPTMnetiQ9BQ49
PhosphoSitePlusiQ9BQ49

Expressioni

Gene expression databases

BgeeiENSG00000214046
CleanExiHS_C19orf42
ExpressionAtlasiQ9BQ49 baseline and differential
GenevisibleiQ9BQ49 HS

Organism-specific databases

HPAiHPA043127

Interactioni

Protein-protein interaction databases

BioGridi122534, 1 interactor
STRINGi9606.ENSP00000417147

Structurei

3D structure databases

ProteinModelPortaliQ9BQ49
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SMIM7 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J12F Eukaryota
ENOG4111VAP LUCA
GeneTreeiENSGT00390000014626
HOGENOMiHOG000015376
HOVERGENiHBG060869
InParanoidiQ9BQ49
PhylomeDBiQ9BQ49
TreeFamiTF332999

Family and domain databases

InterProiView protein in InterPro
IPR037659 SMIM7
PANTHERiPTHR28622 PTHR28622, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BQ49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGDILLFGT LLMNAGAVLN FKLKKKDTQG FGEESREPST GDNIREFLLS
60 70
LRYFRIFIAL WNIFMMFCMI VLFGS
Length:75
Mass (Da):8,631
Last modified:July 1, 2008 - v2
Checksum:i5CF77700933970D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK025602 mRNA No translation available.
AC024075 Genomic DNA No translation available.
BC001680 mRNA No translation available.
BC001948 mRNA No translation available.
CCDSiCCDS12348.2
RefSeqiNP_077009.2, NM_024104.3
UniGeneiHs.356467

Genome annotation databases

EnsembliENST00000481671; ENSP00000433833; ENSG00000214046
ENST00000487416; ENSP00000417147; ENSG00000214046
ENST00000593404; ENSP00000471355; ENSG00000214046
ENST00000593409; ENSP00000469962; ENSG00000214046
ENST00000597781; ENSP00000469440; ENSG00000214046
ENST00000599310; ENSP00000469918; ENSG00000214046
GeneIDi79086
KEGGihsa:79086
UCSCiuc002ner.4 human

Similar proteinsi

Entry informationi

Entry nameiSMIM7_HUMAN
AccessioniPrimary (citable) accession number: Q9BQ49
Secondary accession number(s): A8MX44
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: July 1, 2008
Last modified: February 28, 2018
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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