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Q9BPY3

- F118B_HUMAN

UniProt

Q9BPY3 - F118B_HUMAN

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Protein

Protein FAM118B

Gene

FAM118B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM118B
Gene namesi
Name:FAM118B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:26110. FAM118B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145008413.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed2 Publications
Chaini2 – 351350Protein FAM118BPRO_0000295103Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine2 Publications
Modified residuei9 – 91Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9BPY3.
PaxDbiQ9BPY3.
PeptideAtlasiQ9BPY3.
PRIDEiQ9BPY3.

PTM databases

PhosphoSiteiQ9BPY3.

Expressioni

Gene expression databases

BgeeiQ9BPY3.
CleanExiHS_FAM118B.
ExpressionAtlasiQ9BPY3. baseline and differential.
GenevestigatoriQ9BPY3.

Organism-specific databases

HPAiHPA041644.
HPA042100.

Interactioni

Protein-protein interaction databases

BioGridi122742. 29 interactions.
IntActiQ9BPY3. 21 interactions.
MINTiMINT-1425805.

Structurei

3D structure databases

ProteinModelPortaliQ9BPY3.
SMRiQ9BPY3. Positions 39-67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM118 family.Curated

Phylogenomic databases

eggNOGiNOG46711.
GeneTreeiENSGT00390000010215.
HOGENOMiHOG000072713.
HOVERGENiHBG055230.
InParanoidiQ9BPY3.
OMAiLYETKSF.
OrthoDBiEOG7RJPRH.
PhylomeDBiQ9BPY3.
TreeFamiTF332439.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BPY3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASTGSQASD IDEIFGFFND GEPPTKKPRK LLPSLKTKKP RELVLVIGTG
60 70 80 90 100
ISAAVAPQVP ALKSWKGLIQ ALLDAAIDFD LLEDEESKKF QKCLHEDKNL
110 120 130 140 150
VHVAHDLIQK LSPRTSNVRS TFFKDCLYEV FDDLESKMED SGKQLLQSVL
160 170 180 190 200
HLMENGALVL TTNFDNLLEL YAADQGKQLE SLDLTDEKKV LEWAQEKRKL
210 220 230 240 250
SVLHIHGVYT NPSGIVLHPA GYQNVLRNTE VMREIQKLYE NKSFLFLGCG
260 270 280 290 300
WTVDDTTFQA LFLEAVKHKS DLEHFMLVRR GDVDEFKKLR ENMLDKGIKV
310 320 330 340 350
ISYGDDYADL PEYFKRLTCE ISTRGTSAGM VREGQLNGSS AAHSEIRGCS

T
Length:351
Mass (Da):39,499
Last modified:June 1, 2001 - v1
Checksum:iD298067C1D17E339
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti133 – 1331D → G in BAB14987. (PubMed:14702039)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024756 mRNA. Translation: BAB14987.1.
CR457334 mRNA. Translation: CAG33615.1.
BC001340 mRNA. Translation: AAH01340.1.
BC001647 mRNA. Translation: AAH01647.1.
CCDSiCCDS8470.1.
RefSeqiNP_078832.1. NM_024556.3.
UniGeneiHs.276315.

Genome annotation databases

EnsembliENST00000533050; ENSP00000433343; ENSG00000197798.
GeneIDi79607.
KEGGihsa:79607.
UCSCiuc001qdf.3. human.

Polymorphism databases

DMDMi74732801.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024756 mRNA. Translation: BAB14987.1 .
CR457334 mRNA. Translation: CAG33615.1 .
BC001340 mRNA. Translation: AAH01340.1 .
BC001647 mRNA. Translation: AAH01647.1 .
CCDSi CCDS8470.1.
RefSeqi NP_078832.1. NM_024556.3.
UniGenei Hs.276315.

3D structure databases

ProteinModelPortali Q9BPY3.
SMRi Q9BPY3. Positions 39-67.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122742. 29 interactions.
IntActi Q9BPY3. 21 interactions.
MINTi MINT-1425805.

PTM databases

PhosphoSitei Q9BPY3.

Polymorphism databases

DMDMi 74732801.

Proteomic databases

MaxQBi Q9BPY3.
PaxDbi Q9BPY3.
PeptideAtlasi Q9BPY3.
PRIDEi Q9BPY3.

Protocols and materials databases

DNASUi 79607.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000533050 ; ENSP00000433343 ; ENSG00000197798 .
GeneIDi 79607.
KEGGi hsa:79607.
UCSCi uc001qdf.3. human.

Organism-specific databases

CTDi 79607.
GeneCardsi GC11P126081.
H-InvDB HIX0010251.
HGNCi HGNC:26110. FAM118B.
HPAi HPA041644.
HPA042100.
neXtProti NX_Q9BPY3.
PharmGKBi PA145008413.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG46711.
GeneTreei ENSGT00390000010215.
HOGENOMi HOG000072713.
HOVERGENi HBG055230.
InParanoidi Q9BPY3.
OMAi LYETKSF.
OrthoDBi EOG7RJPRH.
PhylomeDBi Q9BPY3.
TreeFami TF332439.

Miscellaneous databases

GenomeRNAii 79607.
NextBioi 68646.
PROi Q9BPY3.

Gene expression databases

Bgeei Q9BPY3.
CleanExi HS_FAM118B.
ExpressionAtlasi Q9BPY3. baseline and differential.
Genevestigatori Q9BPY3.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Cervix and Lung.
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF118B_HUMAN
AccessioniPrimary (citable) accession number: Q9BPY3
Secondary accession number(s): Q9H7B0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3