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Q9BPY3

- F118B_HUMAN

UniProt

Q9BPY3 - F118B_HUMAN

Protein

Protein FAM118B

Gene

FAM118B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM118B
    Gene namesi
    Name:FAM118B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:26110. FAM118B.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA145008413.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed2 Publications
    Chaini2 – 351350Protein FAM118BPRO_0000295103Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine2 Publications
    Modified residuei9 – 91Phosphoserine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ9BPY3.
    PaxDbiQ9BPY3.
    PeptideAtlasiQ9BPY3.
    PRIDEiQ9BPY3.

    PTM databases

    PhosphoSiteiQ9BPY3.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9BPY3.
    BgeeiQ9BPY3.
    CleanExiHS_FAM118B.
    GenevestigatoriQ9BPY3.

    Organism-specific databases

    HPAiHPA041644.
    HPA042100.

    Interactioni

    Protein-protein interaction databases

    BioGridi122742. 22 interactions.
    IntActiQ9BPY3. 21 interactions.
    MINTiMINT-1425805.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9BPY3.
    SMRiQ9BPY3. Positions 39-67.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FAM118 family.Curated

    Phylogenomic databases

    eggNOGiNOG46711.
    HOGENOMiHOG000072713.
    HOVERGENiHBG055230.
    InParanoidiQ9BPY3.
    OMAiLYETKSF.
    OrthoDBiEOG7RJPRH.
    PhylomeDBiQ9BPY3.
    TreeFamiTF332439.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9BPY3-1 [UniParc]FASTAAdd to Basket

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    MASTGSQASD IDEIFGFFND GEPPTKKPRK LLPSLKTKKP RELVLVIGTG    50
    ISAAVAPQVP ALKSWKGLIQ ALLDAAIDFD LLEDEESKKF QKCLHEDKNL 100
    VHVAHDLIQK LSPRTSNVRS TFFKDCLYEV FDDLESKMED SGKQLLQSVL 150
    HLMENGALVL TTNFDNLLEL YAADQGKQLE SLDLTDEKKV LEWAQEKRKL 200
    SVLHIHGVYT NPSGIVLHPA GYQNVLRNTE VMREIQKLYE NKSFLFLGCG 250
    WTVDDTTFQA LFLEAVKHKS DLEHFMLVRR GDVDEFKKLR ENMLDKGIKV 300
    ISYGDDYADL PEYFKRLTCE ISTRGTSAGM VREGQLNGSS AAHSEIRGCS 350
    T 351
    Length:351
    Mass (Da):39,499
    Last modified:June 1, 2001 - v1
    Checksum:iD298067C1D17E339
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti133 – 1331D → G in BAB14987. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK024756 mRNA. Translation: BAB14987.1.
    CR457334 mRNA. Translation: CAG33615.1.
    BC001340 mRNA. Translation: AAH01340.1.
    BC001647 mRNA. Translation: AAH01647.1.
    CCDSiCCDS8470.1.
    RefSeqiNP_078832.1. NM_024556.3.
    UniGeneiHs.276315.

    Genome annotation databases

    EnsembliENST00000533050; ENSP00000433343; ENSG00000197798.
    GeneIDi79607.
    KEGGihsa:79607.
    UCSCiuc001qdf.3. human.

    Polymorphism databases

    DMDMi74732801.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK024756 mRNA. Translation: BAB14987.1 .
    CR457334 mRNA. Translation: CAG33615.1 .
    BC001340 mRNA. Translation: AAH01340.1 .
    BC001647 mRNA. Translation: AAH01647.1 .
    CCDSi CCDS8470.1.
    RefSeqi NP_078832.1. NM_024556.3.
    UniGenei Hs.276315.

    3D structure databases

    ProteinModelPortali Q9BPY3.
    SMRi Q9BPY3. Positions 39-67.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122742. 22 interactions.
    IntActi Q9BPY3. 21 interactions.
    MINTi MINT-1425805.

    PTM databases

    PhosphoSitei Q9BPY3.

    Polymorphism databases

    DMDMi 74732801.

    Proteomic databases

    MaxQBi Q9BPY3.
    PaxDbi Q9BPY3.
    PeptideAtlasi Q9BPY3.
    PRIDEi Q9BPY3.

    Protocols and materials databases

    DNASUi 79607.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000533050 ; ENSP00000433343 ; ENSG00000197798 .
    GeneIDi 79607.
    KEGGi hsa:79607.
    UCSCi uc001qdf.3. human.

    Organism-specific databases

    CTDi 79607.
    GeneCardsi GC11P126081.
    H-InvDB HIX0010251.
    HGNCi HGNC:26110. FAM118B.
    HPAi HPA041644.
    HPA042100.
    neXtProti NX_Q9BPY3.
    PharmGKBi PA145008413.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG46711.
    HOGENOMi HOG000072713.
    HOVERGENi HBG055230.
    InParanoidi Q9BPY3.
    OMAi LYETKSF.
    OrthoDBi EOG7RJPRH.
    PhylomeDBi Q9BPY3.
    TreeFami TF332439.

    Miscellaneous databases

    GenomeRNAii 79607.
    NextBioi 68646.
    PROi Q9BPY3.

    Gene expression databases

    ArrayExpressi Q9BPY3.
    Bgeei Q9BPY3.
    CleanExi HS_FAM118B.
    Genevestigatori Q9BPY3.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Cervix and Lung.
    4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiF118B_HUMAN
    AccessioniPrimary (citable) accession number: Q9BPY3
    Secondary accession number(s): Q9H7B0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3