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Q9BPV8

- P2Y13_HUMAN

UniProt

Q9BPV8 - P2Y13_HUMAN

Protein

P2Y purinoceptor 13

Gene

P2RY13

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 126 (01 Oct 2014)
      Sequence version 3 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.1 Publication

    GO - Molecular functioni

    1. G-protein coupled purinergic nucleotide receptor activity Source: Ensembl

    GO - Biological processi

    1. negative regulation of adenylate cyclase activity Source: InterPro

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_18289. P2Y receptors.
    REACT_19231. G alpha (i) signalling events.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    P2Y purinoceptor 13
    Short name:
    P2Y13
    Alternative name(s):
    G-protein coupled receptor 86
    G-protein coupled receptor 94
    Gene namesi
    Name:P2RY13
    Synonyms:GPR86, GPR94
    ORF Names:FKSG77
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:4537. P2RY13.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354P2Y purinoceptor 13PRO_0000070040Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi23 – 231N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi31 – 311N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi116 ↔ 194PROSITE-ProRule annotation
    Glycosylationi285 – 2851N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ9BPV8.
    PRIDEiQ9BPV8.

    PTM databases

    PhosphoSiteiQ9BPV8.

    Expressioni

    Tissue specificityi

    Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined.

    Gene expression databases

    BgeeiQ9BPV8.
    CleanExiHS_P2RY13.
    GenevestigatoriQ9BPV8.

    Organism-specific databases

    HPAiHPA049047.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000320376.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2B6Umodel-A22-354[»]
    ProteinModelPortaliQ9BPV8.
    SMRiQ9BPV8. Positions 36-331.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 4949ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini71 – 777CytoplasmicSequence Analysis
    Topological domaini99 – 11719ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini139 – 16123CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini183 – 21129ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini233 – 25220CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini274 – 30027ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini322 – 33312CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei50 – 7021Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei78 – 9821Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei118 – 13821Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei162 – 18221Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei212 – 23221Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei253 – 27321Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei301 – 32121Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG148143.
    HOVERGENiHBG108228.
    InParanoidiQ9BPV8.
    KOiK08388.
    OMAiFYVVIAK.
    OrthoDBiEOG7JQBNQ.
    PhylomeDBiQ9BPV8.
    TreeFamiTF330969.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR008109. P2Y13_rcpt.
    [Graphical view]
    PANTHERiPTHR24233:SF7. PTHR24233:SF7. 1 hit.
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR01735. P2Y13PRNCPTR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9BPV8-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MTAAIRRQRE LSILPKVTLE AMNTTVMQGF NRSERCPRDT RIVQLVFPAL    50
    YTVVFLTGIL LNTLALWVFV HIPSSSTFII YLKNTLVADL IMTLMLPFKI 100
    LSDSHLAPWQ LRAFVCRFSS VIFYETMYVG IVLLGLIAFD RFLKIIRPLR 150
    NIFLKKPVFA KTVSIFIWFF LFFISLPNTI LSNKEATPSS VKKCASLKGP 200
    LGLKWHQMVN NICQFIFWTV FILMLVFYVV IAKKVYDSYR KSKSKDRKNN 250
    KKLEGKVFVV VAVFFVCFAP FHFARVPYTH SQTNNKTDCR LQNQLFIAKE 300
    TTLFLAATNI CMDPLIYIFL CKKFTEKLPC MQGRKTTASS QENHSSQTDN 350
    ITLG 354
    Length:354
    Mass (Da):40,789
    Last modified:February 8, 2011 - v3
    Checksum:iA2CE5F8ED84C4CAF
    GO
    Isoform 2 (identifier: Q9BPV8-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-21: Missing.

    Show »
    Length:333
    Mass (Da):38,410
    Checksum:i3F88E7EAC8F5428F
    GO

    Sequence cautioni

    The sequence AAH29363.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
    The sequence AAH41116.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAG36024.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti179 – 1791T → M.8 Publications
    Corresponds to variant rs1466684 [ dbSNP | Ensembl ].
    VAR_028299

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 2121Missing in isoform 2. 3 PublicationsVSP_036226Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF411113 Genomic DNA. Translation: AAL26484.1.
    AF406692 mRNA. Translation: AAL01038.1.
    AF295368 mRNA. Translation: AAK01864.1.
    AF345565 mRNA. Translation: AAK29068.1.
    AB083597 Genomic DNA. Translation: BAB89310.1.
    AK313208 mRNA. Translation: BAG36024.1. Different initiation.
    AC024886 Genomic DNA. No translation available.
    CH471052 Genomic DNA. Translation: EAW78805.1.
    BC029363 mRNA. Translation: AAH29363.1. Sequence problems.
    BC041116 mRNA. Translation: AAH41116.2. Different initiation.
    BC066887 mRNA. Translation: AAH66887.1.
    AF178982 mRNA. Translation: AAK18752.1.
    CCDSiCCDS3158.2. [Q9BPV8-1]
    RefSeqiNP_795713.2. NM_176894.2. [Q9BPV8-1]
    UniGeneiHs.546396.

    Genome annotation databases

    EnsembliENST00000325602; ENSP00000320376; ENSG00000181631. [Q9BPV8-1]
    GeneIDi53829.
    KEGGihsa:53829.
    UCSCiuc003eyv.2. human. [Q9BPV8-1]

    Polymorphism databases

    DMDMi322510112.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF411113 Genomic DNA. Translation: AAL26484.1 .
    AF406692 mRNA. Translation: AAL01038.1 .
    AF295368 mRNA. Translation: AAK01864.1 .
    AF345565 mRNA. Translation: AAK29068.1 .
    AB083597 Genomic DNA. Translation: BAB89310.1 .
    AK313208 mRNA. Translation: BAG36024.1 . Different initiation.
    AC024886 Genomic DNA. No translation available.
    CH471052 Genomic DNA. Translation: EAW78805.1 .
    BC029363 mRNA. Translation: AAH29363.1 . Sequence problems.
    BC041116 mRNA. Translation: AAH41116.2 . Different initiation.
    BC066887 mRNA. Translation: AAH66887.1 .
    AF178982 mRNA. Translation: AAK18752.1 .
    CCDSi CCDS3158.2. [Q9BPV8-1 ]
    RefSeqi NP_795713.2. NM_176894.2. [Q9BPV8-1 ]
    UniGenei Hs.546396.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2B6U model - A 22-354 [» ]
    ProteinModelPortali Q9BPV8.
    SMRi Q9BPV8. Positions 36-331.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000320376.

    Chemistry

    GuidetoPHARMACOLOGYi 329.

    Protein family/group databases

    GPCRDBi Search...

    PTM databases

    PhosphoSitei Q9BPV8.

    Polymorphism databases

    DMDMi 322510112.

    Proteomic databases

    PaxDbi Q9BPV8.
    PRIDEi Q9BPV8.

    Protocols and materials databases

    DNASUi 53829.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000325602 ; ENSP00000320376 ; ENSG00000181631 . [Q9BPV8-1 ]
    GeneIDi 53829.
    KEGGi hsa:53829.
    UCSCi uc003eyv.2. human. [Q9BPV8-1 ]

    Organism-specific databases

    CTDi 53829.
    GeneCardsi GC03M151044.
    H-InvDB HIX0200553.
    HGNCi HGNC:4537. P2RY13.
    HPAi HPA049047.
    MIMi 606380. gene.
    neXtProti NX_Q9BPV8.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG148143.
    HOVERGENi HBG108228.
    InParanoidi Q9BPV8.
    KOi K08388.
    OMAi FYVVIAK.
    OrthoDBi EOG7JQBNQ.
    PhylomeDBi Q9BPV8.
    TreeFami TF330969.

    Enzyme and pathway databases

    Reactomei REACT_18289. P2Y receptors.
    REACT_19231. G alpha (i) signalling events.

    Miscellaneous databases

    GeneWikii P2RY13.
    GenomeRNAii 53829.
    NextBioi 56152.
    PROi Q9BPV8.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9BPV8.
    CleanExi HS_P2RY13.
    Genevestigatori Q9BPV8.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR008109. P2Y13_rcpt.
    [Graphical view ]
    PANTHERi PTHR24233:SF7. PTHR24233:SF7. 1 hit.
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR01735. P2Y13PRNCPTR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Discovery and mapping of ten novel G protein-coupled receptor genes."
      Lee D.K., Nguyen T., Lynch K.R., Cheng R., Vanti W.B., Arkhitko O., Lewis T., Evans J.F., George S.R., O'Dowd B.F.
      Gene 275:83-91(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], ALTERNATIVE SPLICING (ISOFORM 2), VARIANT MET-179.
    2. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, VARIANT MET-179.
      Tissue: Spleen.
    3. "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors."
      Wittenberger T., Schaller H.C., Hellebrand S.
      J. Mol. Biol. 307:799-813(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT MET-179.
      Tissue: Amygdala, Caudate nucleus, Fetal brain and Placenta.
    4. "Molecular cloning of FKSG77, a novel gene encoding a putative G-protein-coupled receptor."
      Wang Y.-G., Gong L.
      Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT MET-179.
      Tissue: Heart.
    5. "Identification of G protein-coupled receptor genes from the human genome sequence."
      Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.
      FEBS Lett. 520:97-101(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT MET-179.
    7. "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
      , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
      Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT MET-179.
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT MET-179.
      Tissue: Brain and Placenta.
    10. "Molecular cloning of a probable G protein-coupled receptor with three transmembrane domains."
      Zhang W., Wan T., Cao X.
      Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 172-354, VARIANT MET-179.

    Entry informationi

    Entry nameiP2Y13_HUMAN
    AccessioniPrimary (citable) accession number: Q9BPV8
    Secondary accession number(s): B2R827
    , Q05C50, Q6DKN4, Q8IUT5, Q8TDU7, Q9BY61
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 126 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    6. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    7. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3