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Q9BPF3 (CT121_CONPE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Conotoxin Pn-B01121
OrganismConus pennaceus (Feathered cone) (Conus episcopus)
Taxonomic identifier37335 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Protein attributes

Sequence length64 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted By similarity.

Tissue specificity

Expressed by the venom duct.

Domain

The cysteine framework is V (CC-CC).

Sequence similarities

Belongs to the conotoxin T superfamily.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionToxin
   PTMAmidation
Cleavage on pair of basic residues
Disulfide bond
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionion channel inhibitor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Propeptide23 – 4826 By similarity
PRO_0000274080
Peptide51 – 6313Conotoxin Pn-B01121
PRO_0000274081

Amino acid modifications

Modified residue631Tryptophan amide By similarity
Disulfide bond52 ↔ 59 By similarity
Disulfide bond53 ↔ 60 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9BPF3 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 5E5A04C6B6ADDF88

FASTA647,146
        10         20         30         40         50         60 
MCCLPVFVIL LLLIASAPSV DALPKTKDDM SLASFHDNAK RTLQILSNKR YCCVYDYSCC 


LSWG 

« Hide

References

[1]"Mechanisms for evolving hypervariability: the case of conopeptides."
Conticello S.G., Gilad Y., Avidan N., Ben-Asher E., Levy Z., Fainzilber M.
Mol. Biol. Evol. 18:120-131(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Venom duct.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF214976 mRNA. Translation: AAG60404.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

ConoServer663. Pn-B01121 precursor.

Family and domain databases

InterProIPR004214. Conotoxin.
[Graphical view]
PfamPF02950. Conotoxin. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCT121_CONPE
AccessionPrimary (citable) accession number: Q9BPF3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families