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Protein
Submitted name:

Putative helicase Ski2

Gene

tst

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • helicase activity Source: FlyBase
  • RNA binding Source: InterPro
  • RNA helicase activity Source: InterPro

GO - Biological processi

  • regulation of alternative mRNA splicing, via spliceosome Source: FlyBase
  • RNA catabolic process Source: InterPro

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-429958. mRNA decay by 3' to 5' exoribonuclease.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative helicase Ski2Imported
Gene namesi
Name:tstImported
Synonyms:Ski2Imported
ORF Names:CG10210Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0039117. tst.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: FlyBase

PTM / Processingi

Proteomic databases

PaxDbiQ9BI21.
PRIDEiQ9BI21.

Expressioni

Gene expression databases

BgeeiFBgn0039117.

Structurei

3D structure databases

ProteinModelPortaliQ9BI21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini271 – 427Helicase ATP-bindingInterPro annotationAdd BLAST157
Domaini535 – 708Helicase C-terminalInterPro annotationAdd BLAST174

Phylogenomic databases

eggNOGiKOG0948. Eukaryota.
COG4581. LUCA.
OrthoDBiEOG091G0184.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR025696. rRNA_proc-arch_dom.
IPR016438. Ski2.
IPR012961. Ski2_C.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF08148. DSHCT. 1 hit.
PF00271. Helicase_C. 1 hit.
PF13234. rRNA_proc-arch. 1 hit.
PIRSFiPIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM01142. DSHCT. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9BI21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEIRGEDNL ERLRNYILRP ELSLHNPLPD VLPRKFDPMR LLHAPRCPGS
60 70 80 90 100
TKLAPRRDQS GHILEFVELD LEAVGANANN SMSMQREPGL LEDATRGSHS
110 120 130 140 150
NFPFWPGGFD EQRQQIAALD VSNFQFGDKL LTVPPGFSSG YDFFQSQSVT
160 170 180 190 200
LPPVVADPSN VDLLENLEQD LDVQEWMKLT RSEETSSTGT PKSPKQSNVQ
210 220 230 240 250
LPSEEFRDVD DHIMKADLKP VLNISTTTKN FKSDWAEMVD ISQPINNFKE
260 270 280 290 300
QIPCPAMDFP FELDVFQKQA ILKLEQRQYV FVAAHTSAGK TVVAEYAIAL
310 320 330 340 350
SKRDLTRTIY TSPIKALSNQ KYRDFRKTFK DVGLITGDLQ IEPTASCLIM
360 370 380 390 400
TTEILRSMLY CGSDVTRDLE WVIFDEVHYI NNPERGHVWE EVIILLPEHV
410 420 430 440 450
NIIMLSATVP NTLELADWVG STKKRKVYVI STLKRPVPLT HFLYTGAGGK
460 470 480 490 500
SRDDIFLLVD AQGKYLQGNY EKAVERKKEM QGKAKGGGGG PRNHLNAKQE
510 520 530 540 550
QYTWIGLIDF LRRSNMMPVV AFTLSRNRCD SNLAALQSVD LNTEKEKGAV
560 570 580 590 600
QKFFLQCLAK LKPPDRTIPQ VLVLKDALER GIGVHHSGIL PILKEIVEML
610 620 630 640 650
FQNGLVKLLF ATETFAMGVN MPARTVVFDS CKKFDGLEMR NLKPGEYIQM
660 670 680 690 700
AGRAGRRGHD ETGTAIIMCK GSVPPSMELR PMILGLPEKL QSQFILRYAV
710 720 730 740 750
ILTCLRIESI KVEDIMKFSF KEFNLKLQLP TQQKQLRLAE DKFAMLPTLG
760 770 780 790 800
EHLQPLVNFY DKAVEYWKEK HRIMKFVVTQ PKIQKELKAG RVIVITQGKH
810 820 830 840 850
YNKLAILLNT KSVPGKDTIY KVLVLDHQFK AKDSNSLQQG ELYYKILSLT
860 870 880 890 900
PRNMTFQPVG IGGHTVLDIK AIDIISITKS TLKVDADAII RNWEQRQLER
910 920 930 940 950
FKDSPPSGSV VKAVTELNQL NESYIDNPDN IKYVNLSKEI IVNADSEVAM
960 970 980 990 1000
LNYVDHLLRK VGEFLPHTNI AGFEQEFAKV YERRMLEIHI EELRFKNSAR
1010 1020 1030 1040 1050
NLTLYPDYCN KLKVLRALKY IDELDEVTLK GKVACEMGQN ELLITELILC
1060 1070 1080 1090 1100
NMFNDLEPAE IAALLSGLVF QAKMQDKPVI PEALKECVAA FEQINDTILA
1110 1120 1130 1140 1150
EEQRFQAAIE TDNRLNFGLL EVVYEWARNK PFAEIMKLTT VQEGIIVRCI
1160 1170 1180 1190
QQLNETVRDV KTAAIRIGNP GLQSKMEEAS AAIKRDIVFT ASLYTEL
Length:1,197
Mass (Da):135,754
Last modified:June 1, 2001 - v1
Checksum:iE125AB5DE57217A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ276896 mRNA. Translation: CAC35050.1.

Entry informationi

Entry nameiQ9BI21_DROME
AccessioniPrimary (citable) accession number: Q9BI21
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 5, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)