Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cocaine- and amphetamine-regulated transcript protein

Gene

CARTPT

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide, Neurotransmitter

Names & Taxonomyi

Protein namesi
Recommended name:
Cocaine- and amphetamine-regulated transcript protein
Cleaved into the following 2 chains:
Gene namesi
Name:CARTPT
Synonyms:CART
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000453821 – ›66Cocaine- and amphetamine-regulated transcript proteinAdd BLAST›66
PeptideiPRO_000000444021 – ›66CART(55-102)By similarityAdd BLAST›46
PeptideiPRO_000000444128 – ›66CART(62-102)By similarityAdd BLAST›39

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi34 ↔ 52By similarity
Disulfide bondi40 ↔ 60By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Proteomic databases

PaxDbiQ9BDP9.
PeptideAtlasiQ9BDP9.
PRIDEiQ9BDP9.

Expressioni

Gene expression databases

GenevisibleiQ9BDP9. SS.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017982.

Structurei

3D structure databases

ProteinModelPortaliQ9BDP9.
SMRiQ9BDP9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CART family.Curated

Phylogenomic databases

eggNOGiENOG410J0KJ. Eukaryota.
ENOG410YRI1. LUCA.
InParanoidiQ9BDP9.
OrthoDBiEOG091G0Y1C.

Family and domain databases

Gene3Di4.10.40.30. 1 hit.
InterProiView protein in InterPro
IPR009106. CART.
PANTHERiPTHR16655. PTHR16655. 1 hit.
PfamiView protein in Pfam
PF06373. CART. 1 hit.
SUPFAMiSSF64546. SSF64546. 1 hit.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BDP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HEKELIEALQ EVLKKLKSKR IPIYEKKYGQ VPMCDAGEQC AVRKGARIGK
60
LCDCPRGTSC NSFLLK
Length:66
Mass (Da):7,451
Last modified:June 1, 2001 - v1
Checksum:iD217D4B6E94155F1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei661

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF338229 mRNA. Translation: AAK26325.1.
UniGeneiSsc.15900.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCART_PIG
AccessioniPrimary (citable) accession number: Q9BDP9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: June 1, 2001
Last modified: March 15, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families