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Protein
Submitted name:

H2-T22 protein

Gene

H2-T22

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-1236974 ER-Phagosome pathway
R-MMU-1236977 Endosomal/Vacuolar pathway
R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
R-MMU-6798695 Neutrophil degranulation
R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Names & Taxonomyi

Protein namesi
Submitted name:
H2-T22 proteinImported
Submitted name:
Histocompatibility 2, T region locus 22Imported
Gene namesi
Name:H2-T22Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:95956 H2-T22

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501431265220 – 344Sequence analysisAdd BLAST325

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi126 ↔ 176Combined sources
Disulfide bondi135 ↔ 158Combined sources
Disulfide bondi215 ↔ 271Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000056116

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YPZX-ray3.40A/C29-288[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini197 – 275Ig-likeInterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00740000114936
HOGENOMiHOG000296917
HOVERGENiHBG016709
KOiK06751

Family and domain databases

Gene3Di2.60.40.101 hit
3.30.500.101 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9BCZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWVLRAAVV CALLLQLDAR PSWTRIPLGS HSLRYFYTAV SRPGLGEPWF
60 70 80 90 100
IIVGYVDDMQ VLRFSSKEET PRMAPWLEQE EADNWEQQTR IVTIQGQLSE
110 120 130 140 150
RNLMTLVHFY NKSMDDSHTL QWLQGCDVEP DRHLCLWYNQ LAYDSEDLPT
160 170 180 190 200
LNENPSSCTV GNSTVPHISQ DLKSHCSDLL QKYLEKGKER LLRSDPPKAH
210 220 230 240 250
VTRHPRPEGD VTLRCWALGF YPADITLTWQ LNGEELTQDM ELVETRPAGD
260 270 280 290 300
GTFQKWAAVV VPLGKEQSYT CHVYHEGLPE PLILRWGGRG RRDTQEAGRD
310 320 330 340
SPQDSSKTVV DDEEMGVCFW KIKSCKTCLG HSPGTSVGES LLSP
Length:344
Mass (Da):39,100
Last modified:June 1, 2001 - v1
Checksum:iA8FE34EE998E614C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112970 Genomic DNA No translation available.
BC003819 mRNA Translation: AAH03819.1
RefSeqiNP_001334311.1, NM_001347382.1
XP_017172753.1, XM_017317264.1
UniGeneiMm.195061

Genome annotation databases

EnsembliENSMUST00000058801; ENSMUSP00000056041; ENSMUSG00000056116
GeneIDi15039
KEGGimmu:15039
UCSCiuc008cjv.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9BCZ1_MOUSE
AccessioniPrimary (citable) accession number: Q9BCZ1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 153 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported