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Protein
Submitted name:

H2-T22 protein

Gene

H2-T22

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
H2-T22 proteinImported
Submitted name:
Protein H2-T22Imported
Gene namesi
Name:H2-T22Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:95956. H2-T22.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 344325Sequence analysisPRO_5007215730Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi126 ↔ 176Combined sources
Disulfide bondi135 ↔ 158Combined sources
Disulfide bondi215 ↔ 271Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YPZX-ray3.40A/C29-288[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini197 – 27579Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118960.
HOGENOMiHOG000296917.
HOVERGENiHBG016709.
OrthoDBiEOG7JT6WQ.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BCZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWVLRAAVV CALLLQLDAR PSWTRIPLGS HSLRYFYTAV SRPGLGEPWF
60 70 80 90 100
IIVGYVDDMQ VLRFSSKEET PRMAPWLEQE EADNWEQQTR IVTIQGQLSE
110 120 130 140 150
RNLMTLVHFY NKSMDDSHTL QWLQGCDVEP DRHLCLWYNQ LAYDSEDLPT
160 170 180 190 200
LNENPSSCTV GNSTVPHISQ DLKSHCSDLL QKYLEKGKER LLRSDPPKAH
210 220 230 240 250
VTRHPRPEGD VTLRCWALGF YPADITLTWQ LNGEELTQDM ELVETRPAGD
260 270 280 290 300
GTFQKWAAVV VPLGKEQSYT CHVYHEGLPE PLILRWGGRG RRDTQEAGRD
310 320 330 340
SPQDSSKTVV DDEEMGVCFW KIKSCKTCLG HSPGTSVGES LLSP
Length:344
Mass (Da):39,100
Last modified:June 1, 2001 - v1
Checksum:iA8FE34EE998E614C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112970 Genomic DNA. No translation available.
BC003819 mRNA. Translation: AAH03819.1.
RefSeqiXP_006523765.1. XM_006523702.2.
UniGeneiMm.195061.

Genome annotation databases

EnsembliENSMUST00000058801; ENSMUSP00000056041; ENSMUSG00000056116.
GeneIDi15039.
UCSCiuc008cjv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112970 Genomic DNA. No translation available.
BC003819 mRNA. Translation: AAH03819.1.
RefSeqiXP_006523765.1. XM_006523702.2.
UniGeneiMm.195061.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YPZX-ray3.40A/C29-288[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000058801; ENSMUSP00000056041; ENSMUSG00000056116.
GeneIDi15039.
UCSCiuc008cjv.1. mouse.

Organism-specific databases

CTDi15039.
MGIiMGI:95956. H2-T22.

Phylogenomic databases

GeneTreeiENSGT00760000118960.
HOGENOMiHOG000296917.
HOVERGENiHBG016709.
OrthoDBiEOG7JT6WQ.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Mix FVB/NImported.
    Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
  2. "Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22."
    Adams E.J., Chien Y.H., Garcia K.C.
    Science 308:227-231(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 29-288, DISULFIDE BONDS.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9BCZ1_MOUSE
AccessioniPrimary (citable) accession number: Q9BCZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 11, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.