Reviewed, UniProtKB/Swiss-Prot Q9B8D5 (ATP9_CANAL)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit 9, mitochondrial
Alternative name(s):
    Lipid-binding protein

Gene names

Name:	ATP9
ORF Names:	CaalfMp05

Encoded on

Mitochondrion

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	76 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element By similarity.
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Mitochondrion membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ATPase C chain family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Membrane Mitochondrion
Domain	Transmembrane
Ligand	Lipid-binding
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrion Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 76	76	ATP synthase subunit 9, mitochondrial		PRO_0000356858
Regions
	Transmembrane	14 – 34	21	Potential
	Transmembrane	52 – 72	21	Potential
Sites
	Site	59	1	Reversibly protonated during proton transport By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9B8D5-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 07C2F17024E055A5	FASTA	76	7,790
	10 20 30 40 50 60 MQLALAAKYI GASIATLGLG GAAIGIALVF VALINGTSRN PSLRSTLFPQ AILGFALSEA 70 CGLFCLMISF LLLYAV

References

[1]

"Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans." Anderson J.B., Wickens C., Khan M., Cowen L.E., Federspiel N.A., Jones T., Kohn L.M. J. Bacteriol. 183:865-872(2001) [PubMed: 11208783] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF285261 Genomic DNA. Translation: AAG59591.1.
RefSeq	NP_075034.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	802561.
KEGG	cal:CaalfMp05.
Organism-specific databases
CGD	CAF0007370. ATP9.
Phylogenomic databases
HOGENOM	HBG753983.
OrthoDB	EOG9GMWDG.
Family and domain databases
InterPro	IPR000454. ATPase_F0-cplx_csu. IPR020537. ATPase_F0-cplx_csu_DDCD_BS. IPR002379. ATPase_F0/V0-cplx_csu. [Graphical view]
Pfam	PF00137. ATP-synt_C. 1 hit. [Graphical view]
PRINTS	PR00124. ATPASEC.
PROSITE	PS00605. ATPASE_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATP9_CANAL

Accession

Primary (citable) accession number: Q9B8D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 16, 2008
Last sequence update:	June 1, 2001
Last modified:	December 15, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)