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Q9B6D8

- COX3_YARLI

UniProt

Q9B6D8 - COX3_YARLI

Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:COX3
    Encoded oniMitochondrion
    OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
    Taxonomic identifieri284591 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
    ProteomesiUP000001300: Mitochondrion

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 268268Cytochrome c oxidase subunit 3PRO_0000183873Add
    BLAST

    Interactioni

    Subunit structurei

    Composed of at least 11 subunits.

    Protein-protein interaction databases

    STRINGi4952.Q9B6D8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9B6D8.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei23 – 4321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei49 – 6921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei88 – 10821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei141 – 16121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei166 – 18621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei203 – 22321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei246 – 26621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1845.
    HOGENOMiHOG000264954.
    KOiK02262.
    OrthoDBiEOG7V76HP.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9B6D8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLTLKKFQV HPFHLVAPSP WPILVSFSVM SIMLTLVFNM HGFMHNNYWV    50
    VFSAIVAIMT MALWFRDIIS EATYLGDHTL AVRKGLNIGF ILFVVSELFF 100
    FIAIFWAFFH SAMAPTIELG GVWPPVGIEA IGPSELPLLN TILLLCSGAT 150
    LTWSHHALLG GNRFNTLLGL ILTIALAVTF MICQYMEYSN APFTISDGIF 200
    GSVFYFGTGF HGLHIIIGII MLGVSLWRIY TYQLTNNHHV GYETSILYYH 250
    FVDVVWLFLY IVFYWWGT 268
    Length:268
    Mass (Da):30,467
    Last modified:June 1, 2001 - v1
    Checksum:iE1ED609DDBFC5FED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ307410 Genomic DNA. Translation: CAC28101.2.
    PIRiS51505.
    RefSeqiNP_075434.2. NC_002659.1.

    Genome annotation databases

    GeneIDi802599.
    KEGGiyli:YalifMp14.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ307410 Genomic DNA. Translation: CAC28101.2 .
    PIRi S51505.
    RefSeqi NP_075434.2. NC_002659.1.

    3D structure databases

    ProteinModelPortali Q9B6D8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4952.Q9B6D8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 802599.
    KEGGi yli:YalifMp14.

    Phylogenomic databases

    eggNOGi COG1845.
    HOGENOMi HOG000264954.
    KOi K02262.
    OrthoDBi EOG7V76HP.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete mitochondrial genome of Yarrowia lipolytica."
      Kerscher S., Durstewitz G., Casaregola S., Gaillardin C., Brandt U.
      Comp. Funct. Genomics 2:80-90(2001)
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 20460 / W29 / CBS 7504 / IFP29.

    Entry informationi

    Entry nameiCOX3_YARLI
    AccessioniPrimary (citable) accession number: Q9B6D8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3