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Q9B6D8 (COX3_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Encoded onMitochondrion
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Composed of at least 11 subunits.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Cytochrome c oxidase subunit 3
PRO_0000183873

Regions

Transmembrane23 – 4321Helical; Potential
Transmembrane49 – 6921Helical; Potential
Transmembrane88 – 10821Helical; Potential
Transmembrane141 – 16121Helical; Potential
Transmembrane166 – 18621Helical; Potential
Transmembrane203 – 22321Helical; Potential
Transmembrane246 – 26621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9B6D8 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: E1ED609DDBFC5FED

FASTA26830,467
        10         20         30         40         50         60 
MNLTLKKFQV HPFHLVAPSP WPILVSFSVM SIMLTLVFNM HGFMHNNYWV VFSAIVAIMT 

        70         80         90        100        110        120 
MALWFRDIIS EATYLGDHTL AVRKGLNIGF ILFVVSELFF FIAIFWAFFH SAMAPTIELG 

       130        140        150        160        170        180 
GVWPPVGIEA IGPSELPLLN TILLLCSGAT LTWSHHALLG GNRFNTLLGL ILTIALAVTF 

       190        200        210        220        230        240 
MICQYMEYSN APFTISDGIF GSVFYFGTGF HGLHIIIGII MLGVSLWRIY TYQLTNNHHV 

       250        260 
GYETSILYYH FVDVVWLFLY IVFYWWGT 

« Hide

References

[1]"The complete mitochondrial genome of Yarrowia lipolytica."
Kerscher S., Durstewitz G., Casaregola S., Gaillardin C., Brandt U.
Comp. Funct. Genomics 2:80-90(2001)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 20460 / W29 / CBS 7504 / IFP29.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ307410 Genomic DNA. Translation: CAC28101.2.
PIRS51505.
RefSeqNP_075434.2. NC_002659.1.

3D structure databases

ProteinModelPortalQ9B6D8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4952.Q9B6D8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID802599.
KEGGyli:YalifMp14.

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02262.
OrthoDBEOG7V76HP.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_YARLI
AccessionPrimary (citable) accession number: Q9B6D8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families