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Q9B1P9 (COX3_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3A
ORF Names:CaalfMp04
AND
Name:COX3B
ORF Names:CaalfMp15
Encoded onMitochondrion
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000356870

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9B1P9 [UniParc].

Last modified July 5, 2004. Version 2.
Checksum: 270DFCE987B010C7

FASTA26930,422
        10         20         30         40         50         60 
MTNNVRGYLQ LHPFHLVGPS PWPIFTSFSL MDLALSLGLT AHGYIASIWP IFLAIIAVLY 

        70         80         90        100        110        120 
SMTLWFKDII AESTYLGDHT LAVKRGLNQG FLLFVVSEIL IFASLFWAYL HSALNPTMDL 

       130        140        150        160        170        180 
GMQWPPVGIP TISPAELPLL NTIILLASGV TVTYAHHALI NGNRTNTLYG FTYTTILIAL 

       190        200        210        220        230        240 
FVYFQYLEYS YAGFTLSDGV YGSTFFSLTG LHGLHMIMLT IMLMICTWRV YNYDFTNTSH 

       250        260 
VGAETTILYL HVLDVIWLFI YIIVYWWGS 

« Hide

References

[1]"Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans."
Anderson J.B., Wickens C., Khan M., Cowen L.E., Federspiel N.A., Jones T., Kohn L.M.
J. Bacteriol. 183:865-872(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF285261 Genomic DNA. Translation: AAG59590.2.
AF285261 Genomic DNA. Translation: AAG59599.2.
RefSeqNP_075033.2. NC_002653.1.
NP_075042.2. NC_002653.1.

3D structure databases

ProteinModelPortalQ9B1P9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAF0007363.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID802550.
802563.
KEGGcal:CaalfMp04.
cal:CaalfMp15.

Organism-specific databases

CGDCAF0007363. COX3A.
CAF0007403. COX3B.

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02262.
OrthoDBEOG7V76HP.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_CANAL
AccessionPrimary (citable) accession number: Q9B1P9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names