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Q9B1P9

- COX3_CANAL

UniProt

Q9B1P9 - COX3_CANAL

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Protein

Cytochrome c oxidase subunit 3

Gene

COX3A

more
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: CGD

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
  2. hydrogen ion transmembrane transport Source: GOC
  3. mitochondrial electron transport, cytochrome c to oxygen Source: CGD
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COX3A
ORF Names:CaalfMp04
AND
Name:COX3B
ORF Names:CaalfMp15
Encoded oniMitochondrion
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Mitochondrion

Organism-specific databases

CGDiCAF0007363. COX3A.
CAF0007403. COX3B.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial respiratory chain complex IV Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Cytochrome c oxidase subunit 3PRO_0000356870Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5476.CAF0007363.

Structurei

3D structure databases

ProteinModelPortaliQ9B1P9.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121HelicalSequence AnalysisAdd
BLAST
Transmembranei45 – 6521HelicalSequence AnalysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence AnalysisAdd
BLAST
Transmembranei127 – 14721HelicalSequence AnalysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence AnalysisAdd
BLAST
Transmembranei205 – 22521HelicalSequence AnalysisAdd
BLAST
Transmembranei247 – 26721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
HOGENOMiHOG000264954.
InParanoidiQ9B1P9.
KOiK02262.
OrthoDBiEOG7V76HP.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9B1P9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNNVRGYLQ LHPFHLVGPS PWPIFTSFSL MDLALSLGLT AHGYIASIWP
60 70 80 90 100
IFLAIIAVLY SMTLWFKDII AESTYLGDHT LAVKRGLNQG FLLFVVSEIL
110 120 130 140 150
IFASLFWAYL HSALNPTMDL GMQWPPVGIP TISPAELPLL NTIILLASGV
160 170 180 190 200
TVTYAHHALI NGNRTNTLYG FTYTTILIAL FVYFQYLEYS YAGFTLSDGV
210 220 230 240 250
YGSTFFSLTG LHGLHMIMLT IMLMICTWRV YNYDFTNTSH VGAETTILYL
260
HVLDVIWLFI YIIVYWWGS
Length:269
Mass (Da):30,422
Last modified:July 5, 2004 - v2
Checksum:i270DFCE987B010C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF285261 Genomic DNA. Translation: AAG59590.2.
AF285261 Genomic DNA. Translation: AAG59599.2.
RefSeqiNP_075033.2. NC_002653.1.
NP_075042.2. NC_002653.1.

Genome annotation databases

GeneIDi802550.
802563.
KEGGical:CaalfMp04.
cal:CaalfMp15.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF285261 Genomic DNA. Translation: AAG59590.2 .
AF285261 Genomic DNA. Translation: AAG59599.2 .
RefSeqi NP_075033.2. NC_002653.1.
NP_075042.2. NC_002653.1.

3D structure databases

ProteinModelPortali Q9B1P9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAF0007363.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 802550.
802563.
KEGGi cal:CaalfMp04.
cal:CaalfMp15.

Organism-specific databases

CGDi CAF0007363. COX3A.
CAF0007403. COX3B.

Phylogenomic databases

eggNOGi COG1845.
HOGENOMi HOG000264954.
InParanoidi Q9B1P9.
KOi K02262.
OrthoDBi EOG7V76HP.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans."
    Anderson J.B., Wickens C., Khan M., Cowen L.E., Federspiel N.A., Jones T., Kohn L.M.
    J. Bacteriol. 183:865-872(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiCOX3_CANAL
AccessioniPrimary (citable) accession number: Q9B1P9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3