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Protein
Submitted name:

Tail spike protein

Gene

9

Organism
Salmonella phage HK620 (Bacteriophage HK620)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei309 – 3091N-acetyl-D-glucosamineCombined sources
Binding sitei316 – 3161N-acetyl-D-glucosamineCombined sources
Binding sitei345 – 3451GalactoseCombined sources
Binding sitei347 – 3471N-acetyl-D-glucosamineCombined sources
Binding sitei373 – 3731N-acetyl-D-glucosamineCombined sources
Binding sitei394 – 3941N-acetyl-D-glucosamineCombined sources
Binding sitei431 – 4311GlucoseCombined sources
Binding sitei472 – 4721N-acetyl-D-glucosamineCombined sources

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Tail spike proteinImported
Gene namesi
Name:9Imported
OrganismiSalmonella phage HK620 (Bacteriophage HK620)Imported
Taxonomic identifieri155148 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeP22likevirus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000725 Componenti: Genome

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2VJIX-ray1.38A111-710[»]
2VJJX-ray1.59A111-710[»]
2X6WX-ray1.35A111-710[»]
2X6XX-ray1.48A111-710[»]
2X6YX-ray1.35A111-710[»]
2X85X-ray1.50A111-710[»]
4AVZX-ray1.82A111-710[»]
4XKVX-ray2.10A115-710[»]
4XKWX-ray1.45A112-710[»]
4XL9X-ray2.02A114-710[»]
4XLAX-ray1.47A111-710[»]
4XLCX-ray1.85A112-710[»]
4XLEX-ray1.45A115-710[»]
4XLFX-ray1.75A112-710[»]
4XLHX-ray1.91A112-710[»]
4XM3X-ray1.27A112-710[»]
4XMYX-ray1.45A112-710[»]
4XN0X-ray1.75A114-710[»]
4XN3X-ray1.65A115-710[»]
4XNFX-ray1.68A112-710[»]
4XONX-ray2.10A112-710[»]
4XOPX-ray1.59A115-710[»]
4XORX-ray1.50A114-710[»]
4XOTX-ray1.06A114-710[»]
4XQFX-ray1.55A111-710[»]
4XQHX-ray1.71A111-710[»]
4XQIX-ray1.85A112-710[»]
4XR6X-ray1.78A114-710[»]
4YEJX-ray1.40A114-710[»]
4YELX-ray1.72A115-710[»]
ProteinModelPortaliQ9AYY6.
SMRiQ9AYY6. Positions 7-110.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9AYY6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 114111Head_bindingInterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni340 – 3423N-acetyl-D-glucosamine bindingCombined sources
Regioni398 – 4014N-acetyl-D-glucosamine bindingCombined sources
Regioni469 – 4702Glucose bindingCombined sources

Family and domain databases

Gene3Di2.160.20.10. 1 hit.
2.170.14.10. 1 hit.
InterProiIPR009093. P22_tailspike_N.
IPR012334. Pectin_lyas_fold.
IPR011050. Pectin_lyase_fold/virulence.
[Graphical view]
PfamiPF09008. Head_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51126. SSF51126. 1 hit.
SSF51327. SSF51327. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9AYY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSINANVV VSMPSQLFTM ARSFKAVANG KIYIGKIDTD PVNPENRIQV
60 70 80 90 100
YVENEDGSHV PVSQPIIINA AGYPVYNGQI AKFVTVQGHS MAVYDAYGAQ
110 120 130 140 150
QFYFPNVLKY DPDQFRAIIE SPEGAGHVGY QYRRNTGSTM RMVSDVLDER
160 170 180 190 200
VSLWDFHCDP SGNVIQPGPN VDSRQYLQAA IDYVSSNGGG TITIPAGYTW
210 220 230 240 250
YLGSYGVGGI AGHSGIIQLR SNVNLNIEGR IHLSPFFDLK PFQVFVGFDN
260 270 280 290 300
GDPASSGNLE NCHIYGHGVV DFGGYEFGAS SQLRNGVAFG RSYNCSVTGI
310 320 330 340 350
TFQNGDVTWA ITLGWNGYGS NCYVRKCRFI NLVNSSVNAD HSTVYVNCPY
360 370 380 390 400
SGVESCYFSM SSSFARNIAC SVELHQHDTF YRGSTVNGYC RGAYVVMHAA
410 420 430 440 450
EAAGAGSYAY NMQVENNIAV IYGQFVILGS DVTATVSGHL NDVIVSGNIV
460 470 480 490 500
SIGERAAFSA PFGAFIDIGP DNSGASNVQD IQRVLVTGNS FYAPANITDS
510 520 530 540 550
AAITLRANLN GCTFIANNFD CRYMVYNAPG TTSPVVQNLV WDKSNVIGGT
560 570 580 590 600
HANQRAGQNL FDMQFASVVN STIEVQLSCE DLSMFSCILF PASCQLSYSK
610 620 630 640 650
ITVDSAWTKS MSNTAVFEGN QQAGANVYVS YPATVNLTSY NTQGAVPFFS
660 670 680 690 700
TDTNYAWVTS AYSLSINENL DFSPPATYTN KANGQLVGVG YNEIGGVRSV
710
SVRLMLQRQV
Length:710
Mass (Da):76,782
Last modified:June 1, 2001 - v1
Checksum:i80BF4E986193952B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335538 Genomic DNA. Translation: AAK28905.1.
RefSeqiNP_112090.1. NC_002730.1.

Genome annotation databases

GeneIDi920967.
KEGGivg:920967.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335538 Genomic DNA. Translation: AAK28905.1.
RefSeqiNP_112090.1. NC_002730.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2VJIX-ray1.38A111-710[»]
2VJJX-ray1.59A111-710[»]
2X6WX-ray1.35A111-710[»]
2X6XX-ray1.48A111-710[»]
2X6YX-ray1.35A111-710[»]
2X85X-ray1.50A111-710[»]
4AVZX-ray1.82A111-710[»]
4XKVX-ray2.10A115-710[»]
4XKWX-ray1.45A112-710[»]
4XL9X-ray2.02A114-710[»]
4XLAX-ray1.47A111-710[»]
4XLCX-ray1.85A112-710[»]
4XLEX-ray1.45A115-710[»]
4XLFX-ray1.75A112-710[»]
4XLHX-ray1.91A112-710[»]
4XM3X-ray1.27A112-710[»]
4XMYX-ray1.45A112-710[»]
4XN0X-ray1.75A114-710[»]
4XN3X-ray1.65A115-710[»]
4XNFX-ray1.68A112-710[»]
4XONX-ray2.10A112-710[»]
4XOPX-ray1.59A115-710[»]
4XORX-ray1.50A114-710[»]
4XOTX-ray1.06A114-710[»]
4XQFX-ray1.55A111-710[»]
4XQHX-ray1.71A111-710[»]
4XQIX-ray1.85A112-710[»]
4XR6X-ray1.78A114-710[»]
4YEJX-ray1.40A114-710[»]
4YELX-ray1.72A115-710[»]
ProteinModelPortaliQ9AYY6.
SMRiQ9AYY6. Positions 7-110.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi920967.
KEGGivg:920967.

Miscellaneous databases

EvolutionaryTraceiQ9AYY6.

Family and domain databases

Gene3Di2.160.20.10. 1 hit.
2.170.14.10. 1 hit.
InterProiIPR009093. P22_tailspike_N.
IPR012334. Pectin_lyas_fold.
IPR011050. Pectin_lyase_fold/virulence.
[Graphical view]
PfamiPF09008. Head_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51126. SSF51126. 1 hit.
SSF51327. SSF51327. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequence of coliphage HK620 and the evolution of lambdoid phages."
    Clark A.J., Inwood W., Cloutier T., Dhillon T.S.
    J. Mol. Biol. 311:657-679(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related."
    Barbirz S., Muller J.J., Uetrecht C., Clark A.J., Heinemann U., Seckler R.
    Mol. Microbiol. 69:303-316(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.38 ANGSTROMS) OF 111-710 IN COMPLEX WITH GALACTOSE; GLUCOSE AND N-ACETYL-D-GLUCOSAMINE.
  3. "Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity."
    Broeker N.K., Gohlke U., Muller J.J., Uetrecht C., Heinemann U., Seckler R., Barbirz S.
    Glycobiology 23:59-68(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS) OF 111-710 IN COMPLEX WITH GLUCOSE AND N-ACETYL-D-GLUCOSAMINE.
  4. "Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein."
    Gohlke U., Broeker N.K., Kunstmann S., Santer M., Heinemann U., Lipowski R., Seckler R., Barbirz S.
    Submitted (JAN-2015) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.06 ANGSTROMS) OF 114-710.

Entry informationi

Entry nameiQ9AYY6_BPHK6
AccessioniPrimary (citable) accession number: Q9AYY6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 11, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.