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Protein

Profilin

Gene
N/A
Organism
Corylus avellana (European hazel) (Corylus maxima)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.UniRule annotation

Keywords - Ligandi

Actin-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
ProfilinUniRule annotation
OrganismiCorylus avellana (European hazel) (Corylus maxima)Imported
Taxonomic identifieri13451 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeCorylus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

Pathology & Biotechi

Protein family/group databases

Allergomei244. Cor a 2.
3217. Cor a 2.0101.

Interactioni

Subunit structurei

Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9AXH5.
SMRiQ9AXH5. Positions 2-131.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the profilin family.UniRule annotationSAAS annotation

Family and domain databases

InterProiIPR005455. PFN.
IPR027310. Profilin_CS.
[Graphical view]
PANTHERiPTHR11604. PTHR11604. 1 hit.
PfamiPF00235. Profilin. 1 hit.
[Graphical view]
PRINTSiPR00392. PROFILIN.
PR01640. PROFILINPLNT.
SMARTiSM00392. PROF. 1 hit.
[Graphical view]
SUPFAMiSSF55770. SSF55770. 1 hit.
PROSITEiPS00414. PROFILIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9AXH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWQTYGDEH LMCEIEGNRL AAAAIIGHDG SVWAQSSTFP QLKPEEITGV
60 70 80 90 100
MNDFNEPGSL APTGLYLGGT KYMVIQGEPG AVIRRKKGPG GVTVKKTSQA
110 120 130
LIIGIYDEPM TPGQCNMIVE RLGDYLIDQG L
Length:131
Mass (Da):14,142
Last modified:June 1, 2001 - v1
Checksum:i6545957D22F4FDEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF327622 mRNA. Translation: AAK01235.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF327622 mRNA. Translation: AAK01235.1.

3D structure databases

ProteinModelPortaliQ9AXH5.
SMRiQ9AXH5. Positions 2-131.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei244. Cor a 2.
3217. Cor a 2.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR005455. PFN.
IPR027310. Profilin_CS.
[Graphical view]
PANTHERiPTHR11604. PTHR11604. 1 hit.
PfamiPF00235. Profilin. 1 hit.
[Graphical view]
PRINTSiPR00392. PROFILIN.
PR01640. PROFILINPLNT.
SMARTiSM00392. PROF. 1 hit.
[Graphical view]
SUPFAMiSSF55770. SSF55770. 1 hit.
PROSITEiPS00414. PROFILIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization of minor allergen hazelnut profilin."
    Luettkopf D., Schocker F., Scheurer S., Haustein D., Vieths S.
    Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9AXH5_CORAV
AccessioniPrimary (citable) accession number: Q9AXH5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 11, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.