Q9AWL7 (GIGAN_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein GIGANTEA

Gene names

Name:	GI
Ordered Locus Names:	Os01g0182600, LOC_Os01g08700
ORF Names:	P0666G04.27-1, P0666G04.27-2

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	1160 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in regulation of circadian rhythm, and in the control of the photoperiodic flowering. Acts as suppressor of flowering under short-day (SD) and long-day (LD) conditions. Activates Hd1/CONSTANS gene. Ref.5
Subcellular location	Nucleus By similarity.
Induction	Expressed with a circadian rhythm with the highest level 8 hours into the light and the lowest level at dawn. The peak of expression in long days is slightly lower, shifted later and the decrease is slower. Ref.4
Sequence similarities	Belongs to the GIGANTEA family.
Sequence caution	The sequence BAD68053.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Biological rhythms Differentiation Flowering
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Molecular function	Developmental protein
Gene Ontology (GO)
Biological process	cell differentiation Inferred from electronic annotation. Source: UniProtKB-KW flower development Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9AWL7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform 2 (identifier: Q9AWL7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     278-959: Missing.

Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1160	1160	Protein GIGANTEA		PRO_0000087490
Natural variations
	Alternative sequence	278 – 959	682	Missing in isoform 2.		VSP_013910
Experimental info
	Sequence conflict	701	1	Missing Ref.2
	Sequence conflict	1149	1	Missing in CAB56058. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 7, 2005. Version 2. Checksum: F2422C69B5B5C6E3	FASTA	1,160	127,067
	10 20 30 40 50 60 MSASNEKWID GLQFSSLFWP PPQDSQQKQA QILAYVEYFG QFTADSEQFP EDIAQLIQSC 70 80 90 100 110 120 YPSKEKRLVD EVLATFVLHH PEHGHAVVHP ILSRIIDGTL SYDRNGFPFM SFISLFSHTS 130 140 150 160 170 180 EKEYSEQWAL ACGEILRVLT HYNRPIFKVD HQHSEAECSS TSDQASSCES MEKRANGSPR 190 200 210 220 230 240 NEPDRKPLRP LSPWITDILL AAPLGIRSDY FRWCGGVMGK YAAGGELKPP TTAYSRGSGK 250 260 270 280 290 300 HPQLMPSTPR WAVANGAGVI LSVCDEEVAR YETANLTAAA VPALLLPPPT TPLDEHLVAG 310 320 330 340 350 360 LPPLEPYARL FHRYYAIATP SATQRLLFGL LEAPPSWAPD ALDAAVQLVE LLRAAEDYDS 370 380 390 400 410 420 GMRLPKNWMH LHFLRAIGTA MSMRAGIAAD TSAALLFRIL SQPTLLFPPL RHAEGVELHH 430 440 450 460 470 480 EPLGGYVSSY KRQLEVPASE ATIDATAQGI ASMLCAHGPD VEWRICTIWE AAYGLLPLSS 490 500 510 520 530 540 SAVDLPEIVV AAPLQPPTLS WSLYLPLLKV FEYLPRGSPS EACLMRIFVA TVEAILRRTF 550 560 570 580 590 600 PSETSEQSRK PRSQSKNLAV AELRTMIHSL FVESCASMDL ASRLLFVVLT VCVSHQALPG 610 620 630 640 650 660 GSKRPTGSDN HSSEEVTNDS RLTNGRNRCK KRQGPVATFD SYVLAAVCAL SCELQLFPFI 670 680 690 700 710 720 SKNGNHSNLK DSIKIVIPGK TTGISNELHN SISSAILHTR RILGILEALF SLKPSSVGTS 730 740 750 760 770 780 WSYSSNEIVA AAMVAAHVSE LFRRSRPCLN ALSALKQCKW DAEISTRASS LYHLIDLHGK 790 800 810 820 830 840 TVTSIVNKAE PLEAHLTLTP VKKDEPPIEE KNINSSDGGA LEKKDASRSH RKNGFARPLL 850 860 870 880 890 900 KCAEDVILNG DVASTSGKAI ASLQVEASDL ANFLTMDRNG GYRGSQTLLR SVLSEKQELC 910 920 930 940 950 960 FSVVSLLWQK LIASPEMQMS AESTSAHQGW RKVVDALCDI VSASPTKASA AIVLQAEKDL 970 980 990 1000 1010 1020 QPWIARDDEQ GQKMWRVNQR IVKLIAELMR NHDSPEALVI LASASDLLLR ATDGMLVDGE 1030 1040 1050 1060 1070 1080 ACTLPQLELL EVTARAVHLI VEWGDSGVSV ADGLSNLLKC RLSTTIRCLS HPSAHVRALS 1090 1100 1110 1120 1130 1140 MSVLRDILNS GQINSSKLIQ GEHRNGIQSP TYQCLAASII NWQADVERCI EWEAHSRRAT 1150 1160 GLTLAFLTAA AKELGCPLTC
	Isoform 2 [UniParc]. Checksum: 1F4DE2C0ED47B2D8	FASTA	478	53,079
	10 20 30 40 50 60 MSASNEKWID GLQFSSLFWP PPQDSQQKQA QILAYVEYFG QFTADSEQFP EDIAQLIQSC 70 80 90 100 110 120 YPSKEKRLVD EVLATFVLHH PEHGHAVVHP ILSRIIDGTL SYDRNGFPFM SFISLFSHTS 130 140 150 160 170 180 EKEYSEQWAL ACGEILRVLT HYNRPIFKVD HQHSEAECSS TSDQASSCES MEKRANGSPR 190 200 210 220 230 240 NEPDRKPLRP LSPWITDILL AAPLGIRSDY FRWCGGVMGK YAAGGELKPP TTAYSRGSGK 250 260 270 280 290 300 HPQLMPSTPR WAVANGAGVI LSVCDEEVAR YETANLTLQP WIARDDEQGQ KMWRVNQRIV 310 320 330 340 350 360 KLIAELMRNH DSPEALVILA SASDLLLRAT DGMLVDGEAC TLPQLELLEV TARAVHLIVE 370 380 390 400 410 420 WGDSGVSVAD GLSNLLKCRL STTIRCLSHP SAHVRALSMS VLRDILNSGQ INSSKLIQGE 430 440 450 460 470 HRNGIQSPTY QCLAASIINW QADVERCIEW EAHSRRATGL TLAFLTAAAK ELGCPLTC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: cv. Nipponbare.
[3]	"GIGANTEA: a circadian clock-controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane-spanning domains." Fowler S., Lee K., Onouchi H., Samach A., Richardson K., Morris B., Coupland G., Putterill J. EMBO J. 18:4679-4688(1999) [PubMed: 10469647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 185-1160 (ISOFORM 1).
[4]	"Isolation of rice genes possibly involved in the photoperiodic control of flowering by a fluorescent differential display method." Hayama R., Izawa T., Shimamoto K. Plant Cell Physiol. 43:494-504(2002) [PubMed: 12040096] [Abstract] Cited for: INDUCTION.
[5]	"Adaptation of photoperiodic control pathways produces short-day flowering in rice." Hayama R., Yokoi S., Tamaki S., Yano M., Shimamoto K. Nature 422:719-722(2003) [PubMed: 12700762] [Abstract] Cited for: FUNCTION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003047 Genomic DNA. Translation: BAD68052.1. AP003047 Genomic DNA. Translation: BAD68053.1. Sequence problems. AK067038 mRNA. No translation available. AJ133787 mRNA. Translation: CAB56058.1.
RefSeq	NP_001042220.1. NM_001048755.1.
UniGene	Os.7987.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9AWL7.
Proteomic databases
PRIDE	Q9AWL7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os01g08700.1; LOC_Os01g08700.1; LOC_Os01g08700. LOC_Os01g08700.2; LOC_Os01g08700.2; LOC_Os01g08700. LOC_Os01g08700.3; LOC_Os01g08700.3; LOC_Os01g08700. LOC_Os01g08700.4; LOC_Os01g08700.4; LOC_Os01g08700. LOC_Os01g08700.5; LOC_Os01g08700.5; LOC_Os01g08700. LOC_Os01g08700.6; LOC_Os01g08700.6; LOC_Os01g08700.
GeneID	4325329.
KEGG	osa:4325329.
Organism-specific databases
Gramene	Q9AWL7.
Phylogenomic databases
GeneTree	EPGT00050000017381.
OMA	PGSENEY.
PhylomeDB	Q9AWL7.
ProtClustDB	CLSN2687916.
Family and domain databases
KO	K12124.
ProtoNet	Search...

Entry information

Entry name

GIGAN_ORYSJ

Accession

Primary (citable) accession number: Q9AWL7
Secondary accession number(s): Q5VR72, Q5VR73, Q9SMB2

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	June 7, 2005
Last modified:	December 14, 2011
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program