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Q9AUR7 (COPA2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Coatomer subunit alpha-2
Alternative name(s):
Alpha-coat protein 2
Short name=Alpha-COP 2
Gene names
Ordered Locus Names:Os03g0711500, LOC_Os03g50350
ORF Names:OsJ_011823, OSJNBb0033N16.11
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length1218 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins By similarity.

Subunit structure

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits By similarity.

Subcellular location

Cytoplasm By similarity. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cytoplasmic vesicle › COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it By similarity.

Sequence similarities

Contains 8 WD repeats.

Sequence caution

The sequence AK058652 differs from that shown. Reason: Frameshift at position 659.

The sequence BAF12971.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12181218Coatomer subunit alpha-2
PRO_0000285602

Regions

Repeat7 – 4842WD 1
Repeat49 – 8840WD 2
Repeat91 – 13242WD 3
Repeat133 – 17240WD 4
Repeat202 – 24140WD 5
Repeat246 – 28540WD 6
Repeat288 – 32639WD 7
Repeat363 – 40442WD 8

Experimental info

Sequence conflict6691E → G in AK058652. Ref.5
Sequence conflict11761D → G in AK058652. Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q9AUR7 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: DB50A264741977F9

FASTA1,218136,308
        10         20         30         40         50         60 
MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 

        70         80         90        100        110        120 
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHECPWIVS ASDDQTIRIW 

       130        140        150        160        170        180 
NWQSRTCVAV LTGHNHYVMC ASFHPKEDLV VSASLDQTVR VWDISALRKK SVSPADDILR 

       190        200        210        220        230        240 
LTQMNTDLFG GVDAVVKYVL EGHDRGVNWA SFHPTLPLIV SGADDRQVKI WRMNDTKAWE 

       250        260        270        280        290        300 
VDTLRGHMNN VSCVMFHAKQ DIIVSNSEDK SIRIWDATKR TGIQTFRREH DRFWILSAHP 

       310        320        330        340        350        360 
EMNLLAAGHD SGMIVFKLER ERPAFSVSGD TVFYVKDRFL RFFEFTTQKE VQLAPIRRPG 

       370        380        390        400        410        420 
SVSLNQSPKT LSYSPTENAV LICSDVDGGS YELYIVPKDS AGRADYLQDA KKGAGGSAVF 

       430        440        450        460        470        480 
VARNRFAVLE KSSNQVLVRN LKNEIVKKSP LPIATDAIYY AGTGSLLCKA EDRVTIFDLQ 

       490        500        510        520        530        540 
QRLILGELQA PSVKYVVWSS DMESVALLSK HAVVIANKKL VHRCTLHETI RVKSGAWDEN 

       550        560        570        580        590        600 
GVFIYTTLNH IKYCLPNGDS GIIKTLDVPI YITRVIGNNI FCLDRDGKNK LVTVDASEYI 

       610        620        630        640        650        660 
FKLALLRKRY DHVMSMIKNS QLCGQAVISY LQQKGFPEVA LHFVKDEKTR FNLALESGNI 

       670        680        690        700        710        720 
QIAVASAKEI DDKDHWYRLG IEALRQGNVG IVEYAYQRTK NFERLAFLYL ITGYMDKVGF 

       730        740        750        760        770        780 
MCKIAGQNNN LMGQFHNALY LGDAMKRVEI LENAGQLPLA YITATTHGLT EIADRLAAEL 

       790        800        810        820        830        840 
GENIPSLPEG KARSLLIPPA PLTASGDWPL LRVMRGIFEG GLDATGKAEL EEDDEAAGAD 

       850        860        870        880        890        900 
WGDEGLDIVD ASEAMANGGD GFDAEEGEAN EEDGEEGGWD LEDLELLPEA ETPKNAGNAR 

       910        920        930        940        950        960 
SAVFVAPPPG MPVSLIWTQK SSLAGEHAAA GNFDTAMRLL SRQLGIKNFA PLKPLFLDLH 

       970        980        990       1000       1010       1020 
MGSHSYLHAL ATAPIIPVAV EKGWSESASP NVRGPPALVF TFPQMEDRLK AAYKATTDGK 

      1030       1040       1050       1060       1070       1080 
FPEALRQFLS ILHTIPLIVV DSRREVDEVK ELIEIVREYV LGLRMELKRK ELRDDVNRQQ 

      1090       1100       1110       1120       1130       1140 
ELAAYFTNCK LQRVHMRLVL GSAMGLCYKQ KNFATAEHFA RMLLENNPNE AQARRARQVQ 

      1150       1160       1170       1180       1190       1200 
QQCSGKKDSS ELNYDYRNPF VVCGATYVPI YRGQKDVSCP YCGSRFVPSI EGQLCTICEL 

      1210 
AVVGADASGL VCSPTQLR

« Hide

References

« Hide 'large scale' references
[1]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 644-1218.
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC082645 Genomic DNA. Translation: AAK18837.1.
DP000009 Genomic DNA. Translation: ABF98514.1.
AP008209 Genomic DNA. Translation: BAF12971.1. Sequence problems.
CM000140 Genomic DNA. Translation: EAZ28340.1.
AK058652 mRNA. No translation available.
RefSeqNP_001051057.1. NM_001057592.1.
UniGeneOs.79017.

3D structure databases

ProteinModelPortalQ9AUR7.
ModBaseSearch...

Protein-protein interaction databases

STRING39947.LOC_Os03g50350.1.

Proteomic databases

PaxDbQ9AUR7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os03g50350.1; LOC_Os03g50350.1; LOC_Os03g50350.
GeneID4333886.
KEGGosa:4333886.

Organism-specific databases

GrameneQ9AUR7.

Phylogenomic databases

eggNOGCOG2319.
HOGENOMHOG000195913.
KOK05236.
OMAENSVLLC.

Gene expression databases

ArrayExpressQ9AUR7.

Family and domain databases

Gene3D2.130.10.10. 2 hits.
InterProIPR016391. Coatomer_asu.
IPR010714. Coatomer_asu_C.
IPR006692. Coatomer_WD-assoc_reg.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF04053. Coatomer_WDAD. 1 hit.
PF06957. COPI_C. 1 hit.
PF00400. WD40. 5 hits.
[Graphical view]
PIRSFPIRSF003354. Coatomer_alpha_subunit. 1 hit.
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMSSF50978. WD40_like. 1 hit.
PROSITEPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOPA2_ORYSJ
AccessionPrimary (citable) accession number: Q9AUR7
Secondary accession number(s): Q0DP67, Q10E14
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: June 1, 2001
Last modified: May 29, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents