Protoporphyrinogen oxidase, chloroplastic precursor - Oryza sativa subsp. japonica (Rice)

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Q9AR38 (PPOC_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 67. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Protoporphyrinogen oxidase, chloroplastic
Short name=PPO
EC=1.3.3.4

Alternative name(s):
Protoporphyrinogen oxidase 1

Gene names

Name:	PPOX1
Ordered Locus Names:	Os01g0286600, LOC_Os01g18320
ORF Names:	P0498A12.42

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length	536 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Catalytic activity	Protoporphyrinogen-IX + 3 O₂ = protoporphyrin-IX + 3 H₂O₂.
Cofactor	FAD By similarity.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1. Porphyrin biosynthesis; chlorophyll biosynthesis.
Subcellular location	Plastid › chloroplast Probable.
Sequence similarities	Belongs to the protoporphyrinogen oxidase family.
Sequence caution	The sequence BAD81569.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Chlorophyll biosynthesis Heme biosynthesis Porphyrin biosynthesis
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway protoporphyrinogen IX biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	chloroplast envelope Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	oxygen-dependent protoporphyrinogen oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Transit peptide

1 – 36

Chloroplast Potential

Chain

37 – 536

500

Protoporphyrinogen oxidase, chloroplastic

PRO_0000376074

Regions

Nucleotide binding

62 – 67

FAD Potential

Sequences

Sequence

Length

Mass (Da)

Tools

Q9AR38 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 25D9E3EDD49A97C3
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FASTA

536

56,727

        10         20         30         40         50         60 
MAAAAAAMAT ATSATAAPPL RIRDAARRTR RRGHVRCAVA SGAAEAPAAP GARVSADCVV 

        70         80         90        100        110        120 
VGGGISGLCT AQALATKHGV GDVLVTEARA RPGGNITTAE RAGEGYLWEE GPNSFQPSDP 

       130        140        150        160        170        180 
VLTMAVDSGL KDDLVFGDPN APRFVLWEGK LRPVPSKPGD LPFFDLMSIP GKLRAGLGAL 

       190        200        210        220        230        240 
GVRAPPPGRE ESVEDFVRRN LGAEVFERLI EPFCSGVYAG DPSKLSMKAA FGKVWRLEDT 

       250        260        270        280        290        300 
GGSIIGGTIK TIQERGKNPK PPRDPRLPTP KGQTVASFRK GLTMLPDAIT SRLGSKVKLS 

       310        320        330        340        350        360 
WKLTSITKSD NKGYALVYET PEGVVSVQAK TVVMTIPSYV ASDILRPLSS DAADALSIFY 

       370        380        390        400        410        420 
YPPVAAVTVS YPKEAIRKEC LIDGELQGFG QLHPRSQGVE TLGTIYSSSL FPNRAPAGRV 

       430        440        450        460        470        480 
LLLNYIGGST NTGIVSKTES ELVEAVDRDL RKMLINPKAV DPLVLGVRVW PQAIPQFLIG 

       490        500        510        520        530 
HLDHLEAAKS ALGKGGYDGL FLGGNYVAGV ALGRCVEGAY ESASQISDYL TKYAYK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of a full length protoporphyrinogen oxidase I cDNA from Oryza sativa L." Ichikawa H., Okano E., Sugita T., Shimizu T., Osakabe K., Toki S. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. Strain: cv. Nipponbare. Tissue: Shoot.
[2]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. Gojobori T. Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB057749 mRNA. Translation: BAB39744.1. AB057771 Genomic DNA. Translation: BAB39760.1. AP003020 Genomic DNA. Translation: BAD81569.1. Sequence problems. AP008207 Genomic DNA. Translation: BAF04691.1.
RefSeq	NP_001042777.1. NM_001049312.1.
UniGene	Os.5439.
3D structure databases
HSSP	HSSP built from PDB template 1SEZ based on UniProtKB O24164.
ProteinModelPortal	Q9AR38.
ModBase	Search...
Proteomic databases
PRIDE	Q9AR38.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os01g18320.1; LOC_Os01g18320.1; LOC_Os01g18320.
GeneID	4327918.
KEGG	dosa:Os01t0286600-01. osa:4327918.
Organism-specific databases
Gramene	Q9AR38.
Phylogenomic databases
eggNOG	COG1232.
HOGENOM	HOG000269479.
KO	K00231.
OMA	SWPGKLR.
ProtClustDB	PLN02576.
Enzyme and pathway databases
UniPathway	UPA00251; UER00324. UPA00668.
Gene expression databases
ArrayExpress	Q9AR38.
Family and domain databases
InterPro	IPR002937. Amino_oxidase. IPR004572. Protoporphyrinogen_oxidase. [Graphical view]
Pfam	PF01593. Amino_oxidase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00562. proto_IX_ox. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPOC_ORYSJ

Accession

Primary (citable) accession number: Q9AR38
Secondary accession number(s): Q5NAD7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 26, 2009
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents