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Protein

Glyceraldehyde-3-phosphate dehydrogenase

Gene

gap

Organism
Streptococcus agalactiae
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi21Magnesium; via carbonyl oxygenCombined sources1
Metal bindingi24Magnesium; via carbonyl oxygenCombined sources1
Metal bindingi27Magnesium; via carbonyl oxygenCombined sources1
Binding sitei34NADCombined sources1
Binding sitei78NAD; via carbonyl oxygenCombined sources1
Binding sitei99NADCombined sources1
Binding sitei121NADCombined sources1
Active sitei152NucleophileUniRule annotation1
Sitei179Activates thiol group during catalysisUniRule annotation1
Binding sitei182Glyceraldehyde 3-phosphateUniRule annotation1
Binding sitei235Glyceraldehyde 3-phosphateUniRule annotation1
Binding sitei316NADCombined sources1
Binding sitei320NADCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 13NADCombined sources2

GO - Molecular functioni

  • glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: CAFA
  • metal ion binding Source: UniProtKB-KW
  • NAD binding Source: CAFA
  • NADP binding Source: InterPro

GO - Biological processi

  • glucose metabolic process Source: InterPro
  • glycolytic process Source: CAFA

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandMagnesiumCombined sources, Metal-bindingCombined sources, NADCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Recommended name:
Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.-UniRule annotation)
Gene namesi
Name:gapImported
ORF Names:AX245_09885Imported, DX05_09270Imported, EN72_09590Imported, RDF_1710Imported
OrganismiStreptococcus agalactiaeImported
Taxonomic identifieri1311 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000093122 Componenti: Unassembled WGS sequence
  • UP000031749 Componenti: Chromosome
  • UP000028184 Componenti: Chromosome
  • UP000035305 Componenti: Chromosome

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5JY6X-ray2.00A/B/C/D1-336[»]
5JYAX-ray2.85A/B/C/D1-336[»]
5JYEX-ray2.23A/B/C/D1-336[»]
5JYFX-ray2.62A/B/C/D1-336[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 152Gp_dh_NInterPro annotationAdd BLAST150

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni151 – 153Glyceraldehyde 3-phosphate bindingUniRule annotation3
Regioni212 – 213Glyceraldehyde 3-phosphate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C17. Bacteria.
COG0057. LUCA.
KOiK00134.

Family and domain databases

InterProiView protein in InterPro
IPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006424. Glyceraldehyde-3-P_DH_1.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
PIRSFiPIRSF000149. GAP_DH. 1 hit.
PRINTSiPR00078. G3PDHDRGNASE.
SMARTiView protein in SMART
SM00846. Gp_dh_N. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01534. GAPDH-I. 1 hit.
PROSITEiView protein in PROSITE
PS00071. GAPDH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ALW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVKVGINGF GRIGRLAFRR IQNVEGVEVT RINDLTDPNM LAHLLKYDTT
60 70 80 90 100
QGRFDGTVEV KEGGFEVNGQ FVKVSAEREP ANIDWATDGV EIVLEATGFF
110 120 130 140 150
ASKEKAEQHI HENGAKKVVI TAPGGNDVKT VVFNTNHDIL DGTETVISGA
160 170 180 190 200
SCTTNCLAPM AKALQDNFGV KQGLMTTIHA YTGDQMILDG PHRGGDLRRA
210 220 230 240 250
RAGAANIVPN STGAAKAIGL VIPELNGKLD GAAQRVPVPT GSVTELVATL
260 270 280 290 300
EKDVTVEEVN AAMKAAANDS YGYTEDPIVS SDIVGISYGS LFDATQTKVQ
310 320 330
TVDGNQLVKV VSWYDNEMSY TSQLVRTLEY FAKIAK
Length:336
Mass (Da):36,006
Last modified:June 1, 2001 - v1
Checksum:i982E18A05CA343C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF338416 Genomic DNA. Translation: AAK14387.1.
CP007631 Genomic DNA. Translation: AIF87322.1.
CP007572 Genomic DNA. Translation: AIK76422.1.
CP010867 Genomic DNA. Translation: AKI96125.1.
MAWT01000022 Genomic DNA. Translation: OCM71507.1.
RefSeqiWP_000260656.1. NZ_NKQA01000058.1.

Genome annotation databases

EnsemblBacteriaiAIF87322; AIF87322; EN72_09590.
AIK76422; AIK76422; DX05_09270.
AKI96125; AKI96125; RDF_1710.
AOQ21664; AOQ21664; BBP08_10800.
CND64643; CND64643; ERS039640_00200.
OCM71507; OCM71507; AX245_09885.
ODG94867; ODG94867; TH70_1537.
KEGGisagc:DN94_07930.
sage:EN72_09590.
sagg:EN73_08665.
sagl:GBS222_1489.
sags:SaSA20_1475.
PATRICifig|1261567.3.peg.1588.

Similar proteinsi

Entry informationi

Entry nameiQ9ALW2_STRAG
AccessioniPrimary (citable) accession number: Q9ALW2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 22, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported