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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:groELUniRule annotation, groEL1UniRule annotation
Ordered Locus Names:VV1_1260
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000635991 – 54660 kDa chaperonin 1Add BLAST546

Proteomic databases

PRIDEiQ9ALA9.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9ALA9.
SMRiQ9ALA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ALA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFGN DARVKMLEGV NILADAVKVT LGPKGRNVVL DKSFGAPTIT
60 70 80 90 100
KDGVSVAREI ELEDKFQNMG AQMVKQVASQ ANDVAGDGTT TATVLAQAIV
110 120 130 140 150
NEGLKAVAAG MNPMDLKRGI DKAVAAAVEE LKALSKDCST STEIEQVGTI
160 170 180 190 200
SANSDSSVGK IIAEAMEKVG RDGVITVEEG QALHDELDVV EGMQFDRGYL
210 220 230 240 250
SPYFINNQES GSVELESPFI LLVDKKISNI RELLPALEAV AKASRPLLII
260 270 280 290 300
AEDVEGEALA TLVVNNMRGI VKVAAVKAPG FGDRRKAMLQ DIAILTGGTV
310 320 330 340 350
ISEEVGLELE KATLEDLGQA KRVSITKENT TIIDGVGEEA MIQGRVAQIR
360 370 380 390 400
QQIEDATSDY DKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL
410 420 430 440 450
HATRAAVEEG IVAGGGVALI RAASKIVDLQ GDNEEQNVGI RVALRAMEAP
460 470 480 490 500
LRQITKNAGD EESVVANNVR AGEGSYGYNA ATGVYGDMLE MGILDPTKVT
510 520 530 540
RSALQFAASV AGLMITTEAM VTDLPQKDSG MPDMGGMGGM GGMGMM
Length:546
Mass (Da):57,516
Last modified:February 1, 2003 - v2
Checksum:i92869B7E517B3D2A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti134L → M in AAG48876 (Ref. 1) Curated1
Sequence conflicti220I → F in AAG48876 (Ref. 1) Curated1
Sequence conflicti256G → D in AAG48876 (Ref. 1) Curated1
Sequence conflicti272K → I in AAG48876 (Ref. 1) Curated1
Sequence conflicti277K → I in AAG48876 (Ref. 1) Curated1
Sequence conflicti388E → K in AAG48876 (Ref. 1) Curated1
Sequence conflicti474G → A in AAG48876 (Ref. 1) Curated1
Sequence conflicti545M → GM (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY017169 Genomic DNA. Translation: AAG48876.1.
AE016795 Genomic DNA. Translation: AAO09716.1.
RefSeqiWP_011079245.1. NC_004459.3.

Genome annotation databases

EnsemblBacteriaiAAO09716; AAO09716; VV1_1260.
GeneIDi33955582.
KEGGivvu:VV1_1260.

Similar proteinsi

Entry informationi

Entry nameiCH601_VIBVU
AccessioniPrimary (citable) accession number: Q9ALA9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: February 1, 2003
Last modified: November 22, 2017
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families