Q9AI29 (Q9AI29_BURMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase WcbS EMBL AAK26475.1

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL AAU49852.1

Gene names

Name:	wcbS EMBL AAK26475.1
Ordered Locus Names:	BMA2288

Organism

Burkholderia mallei (Pseudomonas mallei) [Complete proteome] [HAMAP] EMBL AAK26475.1

Taxonomic identifier

13373 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9AI29 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: EED7108512266A71	FASTA	305	33,143
	10 20 30 40 50 60 MSVPTGWATS QGTLARALTI DGHGLHTGRR VGVRILPARP EDGVTGIAFR RVEQGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGVGVRTVEH LLASLLACEI DHAIVELDAE EVPILDGSAT 130 140 150 160 170 180 PWVDAIRTCG RVALDAPKRF IRVLRTVVVT EGEGEQRREM RIEPAPRYEL SVRNDLRGFG 190 200 210 220 230 240 EMHWDGALTP AAFATEIAPS RSYGRVKWAV PAILAGYLRG MPILRGARPS CTASIVGKRV 250 260 270 280 290 300 LGGMRLPDEF VRHRVLDLVG DLALAGAPLL ARVSAVRPGH EMNFRLVDAL LAEPGAWQWA DFSEA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant." DeShazer D., Waag D.M., Fritz D.L., Woods D.E. Microb. Pathog. 30:253-269(2001) [PubMed: 11373120] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC23344 EMBL AAK26475.1.
[2]	"Structural flexibility in the Burkholderia mallei genome." Nierman W.C., DeShazer D., Kim H.S., Tettelin H., Nelson K.E., Feldblyum T.V., Ulrich R.L., Ronning C.M., Brinkac L.M., Daugherty S.C., Davidsen T.D., DeBoy R.T., Dimitrov G., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Khouri H.M. , Kolonay J.F., Madupu R., Mohammoud Y., Nelson W.C., Radune D., Romero C.M., Sarria S., Selengut J., Shamblin C., Sullivan S.A., White O., Yu Y., Zafar N., Zhou L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 101:14246-14251(2004) [PubMed: 15377793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23344.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF285636 Genomic DNA. Translation: AAK26475.1. CP000010 Genomic DNA. Translation: AAU49852.1.
RefSeq	YP_103850.1. NC_006348.1.
3D structure databases
ProteinModelPortal	Q9AI29.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3090585.
GenomeReviews	Gene locus BMA2288 in contig CP000010_GR.
KEGG	bma:BMA2288.
PATRIC	19119701. VBIBurMal55007_2355.
TIGR	BMA2288.
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
PhylomeDB	Q9AI29.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

Q9AI29_BURMA

Accession

Primary (citable) accession number: Q9AI29
Secondary accession number(s): Q62HH0

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)