Glycosyltransferase GtfD - Amycolatopsis orientalis

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Unreviewed, UniProtKB/TrEMBL Q9AFC7 (Q9AFC7_AMYOR)

Last modified June 16, 2009. Version 29. History...

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Glycosyltransferase GtfD EMBL AAK31352.1

Gene names

Name:

gtfD EMBL AAK31352.1

Organism

Amycolatopsis orientalis EMBL AAK31352.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Amycolatopsis

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Molecular function	Transferase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro lipid glycosylation Inferred from electronic annotation. Source: InterPro
Molecular function	transferase activity, transferring hexosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q9AFC7-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 1233D71CD99D1FBD
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408

42,881

        10         20         30         40         50         60 
MRVLLSVCGT RGDVEIGVAL ADRLKALGVQ TRMCAPPAAE ERLAEVGVPH VPVGLPQHMM 

        70         80         90        100        110        120 
LQEGMPPPPP EEEQRLAAMT VEMQFDAVPG AAEGCAAVVA VGDLAAATGV RSVAEKLGLP 

       130        140        150        160        170        180 
FFYSVPSPVY LASPHLPPAY DEPTTPGVTD IRVLWEERAA RFADRYGPTL NRRRAEIGLP 

       190        200        210        220        230        240 
PVEDVFGYGH GERPCWPADP VLAPLQPDVD AVQTGAWLLS DERPLPPELE AFLAAGSPPV 

       250        260        270        280        290        300 
HIGFGSSSGR GIADAAKVAV EAIRAQGRRV ILSRGWTELV LPDDRDDCFA IDEVNFQALF 

       310        320        330        340        350        360 
RRVAAVIHHG SAGTEHVATR AGVPQLVIPR NTDQPYFAGR VAALGIGVAH DGPTPTFESL 

       370        380        390        400 
SAALTTVLAP ETRARAEAVA GMVLTDGAAA AADLVLAAVG REKPAVPA

References

[1]	"Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides." Losey H.C., Peczuh M.W., Chen Z., Eggert U.S., Dong S.D., Pelczer I., Kahne D., Walsh C.T. Biochemistry 40:4745-4755(2001) [PubMed: 11294642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC19795 EMBL AAK31352.1.
[2]	"Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands." Mulichak A.M., Lu W., Losey H.C., Walsh C.T., Garavito R.M. Biochemistry 43:5170-5180(2004) [PubMed: 15122882] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).

Cross-references

Sequence databases

AF351621 Genomic DNA. Translation: AAK31352.1.

3D structure databases

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1RRV	X-ray	2.00	A/B	1-408	[»]

ModBase

Protein family/group databases

CAZy

GT1. Glycosyltransferase Family 1.

Family and domain databases

InterPro

IPR004276. Glyco_trans_28.
IPR002213. UDP_glucos_trans.
[Graphical view]

PANTHER

PTHR11926. UDP_glucos_trans. 1 hit.

Pfam

PF03033. Glyco_transf_28. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q9AFC7_AMYOR

Accession

Primary (citable) accession number: Q9AFC7

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information