Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathway:iglycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei349 – 3491Proton donorBy similarity
Active sitei380 – 3801By similarity
Active sitei508 – 5081By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCAULO:CC0222-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:CC_0222
OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
ProteomesiUP000001816 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 539539Glucose-6-phosphate isomerasePRO_0000180617Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi190650.CC_0222.

Structurei

3D structure databases

ProteinModelPortaliQ9ABK5.
SMRiQ9ABK5. Positions 4-537.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ABK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLDAAWTR LEAAAKAAGD KRIVEFFDAE PGRLDALTLD VAGLHLDLSK
60 70 80 90 100
QAWDEAGLEA ALDLAHAADV EGARARMFDG EAINSSEGRA VLHTALRAPA
110 120 130 140 150
GADVKALGQP VMAEVDAVRQ RMKAFAQAVR SGAIKGATGK PFKAILHIGI
160 170 180 190 200
GGSDLGPRLL WDALRPVKPS IDLRFVANVD GAEFALTTAD MDPEETLVMV
210 220 230 240 250
VSKTFTTQET MANAGAARAW LVAALGEQGA NQHLAAISTA LDKTAAFGVP
260 270 280 290 300
DDRVFGFWDW VGGRYSLWSS VSLSVAVAAG WDAFQGFLDG GAAMDEHFRT
310 320 330 340 350
APLEQNAPVL VALAQIFNRN GLDRRARSVV PYSHRLRRLA AFLQQLEMES
360 370 380 390 400
NGKSVGPDGQ PAKRGTATVV FGDEGTNVQH AYFQCMHQGT DITPMELIGV
410 420 430 440 450
AKSDEGPAGM HEKLLSNLLA QAEAFMVGRT TDDVVAELTA KGVSDAEIAT
460 470 480 490 500
LAPQRTFAGN RPSTLVLLDR LTPQTFGALI ALYEHKTFVE GVIWGINSFD
510 520 530
QWGVELGKVM ANRILPELES GASGQHDPST AGLIQRLKR
Length:539
Mass (Da):57,526
Last modified:June 1, 2001 - v1
Checksum:iB233DFBAF7FD1595
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK22209.1.
PIRiE87276.
RefSeqiNP_419041.1. NC_002696.2.
WP_010918111.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK22209; AAK22209; CC_0222.
GeneIDi944285.
KEGGiccr:CC_0222.
PATRICi21297360. VBICauCre124313_0218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK22209.1.
PIRiE87276.
RefSeqiNP_419041.1. NC_002696.2.
WP_010918111.1. NC_002696.2.

3D structure databases

ProteinModelPortaliQ9ABK5.
SMRiQ9ABK5. Positions 4-537.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190650.CC_0222.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK22209; AAK22209; CC_0222.
GeneIDi944285.
KEGGiccr:CC_0222.
PATRICi21297360. VBICauCre124313_0218.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciCAULO:CC0222-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19089 / CB15.

Entry informationi

Entry nameiG6PI_CAUCR
AccessioniPrimary (citable) accession number: Q9ABK5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: June 1, 2001
Last modified: June 24, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.