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Q9AAR8

- Q9AAR8_CAUCR

UniProt

Q9AAR8 - Q9AAR8_CAUCR

Protein
Submitted name:

Dihydroorotate dehydrogenase

Gene

CC_0528

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.SAAS annotation

    Catalytic activityi

    (S)-dihydroorotate + a quinone = orotate + a quinol.SAAS annotation

    Cofactori

    Binds 1 FMN per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. dihydroorotate oxidase activity Source: InterPro

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    OxidoreductaseSAAS annotation

    Keywords - Biological processi

    Pyrimidine biosynthesisSAAS annotation

    Keywords - Ligandi

    Flavoprotein, FMNSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00070; UER00946.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Dihydroorotate dehydrogenaseImported
    Gene namesi
    Ordered Locus Names:CC_0528Imported
    OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)Imported
    Taxonomic identifieri190650 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
    ProteomesiUP000001816: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    MembraneSAAS annotation

    Interactioni

    Subunit structurei

    Monomer.SAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ9AAR8.
    SMRiQ9AAR8. Positions 14-351.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000225103.
    KOiK00254.
    OMAiGECIDAF.
    OrthoDBiEOG65BDN8.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR012135. Dihydroorotate_DH_1_2.
    IPR005719. Dihydroorotate_DH_2.
    IPR001295. Dihydroorotate_DH_CS.
    [Graphical view]
    PfamiPF01180. DHO_dh. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000164. DHO_oxidase. 1 hit.
    TIGRFAMsiTIGR01036. pyrD_sub2. 1 hit.
    PROSITEiPS00911. DHODEHASE_1. 1 hit.
    PS00912. DHODEHASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9AAR8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLHDIAARA LHAFDPEDAH GWAIRGLKWG LGPRDAQPDD PILAVKIAGL    50
    ELPNCVGLAA GFDKNAEVPD AMLAAGFGFV EAGTVTPLAQ AGNPRPRLFR 100
    LTEDQAVINR MGFNNGGLEP FAQRLAARQG RGGVVGANIG ANKDATDRIQ 150
    DYVTGLTRLW GLSDYFTANI SSPNTPGLRA LQTKAALEEL LGRLAETRAA 200
    LKVASGADYP IFLKVAPDLE DGEVEAIVET VVGAGLDAII VSNTTIARPE 250
    TLKSRFAGES GGLSGAPLLE ASTAVLARFH AAAAGRVALI GAGGVADGAG 300
    AYAKIRAGAR AVQLYSALVY GGPGLVTRIK RDLAARLRAD GFAAVEDAIG 350
    AA 352
    Length:352
    Mass (Da):36,320
    Last modified:June 1, 2001 - v1
    Checksum:iA53E5216089C2FF9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005673 Genomic DNA. Translation: AAK22515.1.
    PIRiG87314.
    RefSeqiNP_419347.1. NC_002696.2.

    Genome annotation databases

    EnsemblBacteriaiAAK22515; AAK22515; CC_0528.
    GeneIDi941814.
    KEGGiccr:CC_0528.
    PATRICi21298002. VBICauCre124313_0538.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005673 Genomic DNA. Translation: AAK22515.1 .
    PIRi G87314.
    RefSeqi NP_419347.1. NC_002696.2.

    3D structure databases

    ProteinModelPortali Q9AAR8.
    SMRi Q9AAR8. Positions 14-351.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK22515 ; AAK22515 ; CC_0528 .
    GeneIDi 941814.
    KEGGi ccr:CC_0528.
    PATRICi 21298002. VBICauCre124313_0538.

    Phylogenomic databases

    HOGENOMi HOG000225103.
    KOi K00254.
    OMAi GECIDAF.
    OrthoDBi EOG65BDN8.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00946 .

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR012135. Dihydroorotate_DH_1_2.
    IPR005719. Dihydroorotate_DH_2.
    IPR001295. Dihydroorotate_DH_CS.
    [Graphical view ]
    Pfami PF01180. DHO_dh. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000164. DHO_oxidase. 1 hit.
    TIGRFAMsi TIGR01036. pyrD_sub2. 1 hit.
    PROSITEi PS00911. DHODEHASE_1. 1 hit.
    PS00912. DHODEHASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19089 / CB15Imported.

    Entry informationi

    Entry nameiQ9AAR8_CAUCR
    AccessioniPrimary (citable) accession number: Q9AAR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3