ID   Q9A8Y1_CAUVC            Unreviewed;       507 AA.
AC   Q9A8Y1;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 121.
DE   RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE            EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN   OrderedLocusNames=CC_1216 {ECO:0000313|EMBL:AAK23198.1};
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650 {ECO:0000313|EMBL:AAK23198.1, ECO:0000313|Proteomes:UP000001816};
RN   [1] {ECO:0000313|EMBL:AAK23198.1, ECO:0000313|Proteomes:UP000001816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15 {ECO:0000313|Proteomes:UP000001816};
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R., Ohta N., Maddock J.R., Potocka I.,
RA   Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T.,
RA   Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J.,
RA   Craven M.B., Khouri H., Shetty J., Berry K., Utterback T., Tran K.,
RA   Wolf A., Vamathevan J., Ermolaeva M., White O., Salzberg S.L., Venter J.C.,
RA   Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; AE005673; AAK23198.1; -; Genomic_DNA.
DR   PIR; B87400; B87400.
DR   RefSeq; NP_420030.1; NC_002696.2.
DR   RefSeq; WP_010919098.1; NC_002696.2.
DR   AlphaFoldDB; Q9A8Y1; -.
DR   SMR; Q9A8Y1; -.
DR   STRING; 190650.CC_1216; -.
DR   EnsemblBacteria; AAK23198; AAK23198; CC_1216.
DR   KEGG; ccr:CC_1216; -.
DR   PATRIC; fig|190650.5.peg.1240; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_1_2_5; -.
DR   BioCyc; CAULO:CC1216-MONOMER; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07130; ALDH_F7_AASADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR044638; ALDH7A1-like.
DR   PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001816}.
FT   DOMAIN          31..488
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        261
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   507 AA;  53639 MW;  4088076B9C3F233F CRC64;
     MTQVFPTPAA HAREILAKLG APPLPADAGE PVRGPIDGAI LGHVVYDDAR QIEAKVAAAC
     RAFADWRVVP APRRGELVRL FGEELRAAKA DLAALVTLEA GKIASEAAGE VQEMIDICDF
     AVGLSRQLHG LTIASERPGH AMRETWHPLG PVAVISAFNF PVAVWAWNAC LALVCGDPVI
     WKPSEKTPLT ALATQAILER ALARFRDAPQ GLSSVVLGAR DAGERLARDP RIPLVSATGS
     TRMGRAVAPM VAERFGRSIL ELGGNNAMIV TPSADLSLAL RAIVFSAAGT AGQRCTSLRR
     LIVHESLVDK VSDAVEAAFQ RLSVGDPRDP KTLLGPLIDK AAYDAFIAAM NQVRAEGGSV
     AGGERVLIDE HPDAYYVRPA LARLPAPAPC MQRETFAPLL HVVPYNSFDM AIAIQNDVPQ
     GLSSCVMTND VREAERFLAA AGSDCGIANV NIGPSGAEIG GAFGGEKETG GGRESGSDSW
     KQYMRRQTAT VNYSGALPLA QGVRFDL
//