Q9A8J8 (Q9A8J8_CAUCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL AAK23336.1

Gene names

Ordered Locus Names:

CC_1355

Organism

Caulobacter crescentus (Caulobacter vibrioides)

Taxonomic identifier

155892 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Transferase RuleBase RU003693
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9A8J8 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 6167CCFABE604F56	FASTA	408	44,274
	10 20 30 40 50 60 MDYKAAFRSA VEQIREEGRY RVFADLKRQR GQFPRATWTR QDGSEHEVVV WCSNDYLGQG 70 80 90 100 110 120 QNPVVLEAMK AAVDEHGSGS GGTRNISGTN HDHVLLEQEL ADLHGKEAGL LFTSGYVSNE 130 140 150 160 170 180 ATLSVVQKIL PGLIIFSDEL NHASMIAGIR NGGGPRKIFK HNDLAHLEQL LAEAPADAPK 190 200 210 220 230 240 LIAFESVYSM DGDIADLAGT VALAKKYGAM TYLDEVHAVG MYGPRGGGVA ERDGLMGEID 250 260 270 280 290 300 IIEGTLGKAF GVMGGYITGD AEVIDAIRLM ASGFIFTTSL PPALTAGALA SVRWLKQHPE 310 320 330 340 350 360 VREIHQERAA TLKAMFKAAG LPVMDSVSHI VPVLVGDPVH CKMISDMLLA DFGVYVQPIN 370 380 390 400 YPTVPRGTER LRFTPTPFHT DDMMRKLVAA MEKLWAHCNV ARMGGYAA

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed: 11259647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005673 Genomic DNA. Translation: AAK23336.1.
PIR	D87417.
RefSeq	NP_420168.1. NC_002696.2.
3D structure databases
HSSP	HSSP built from PDB template 1FC4 based on UniProtKB P07912.
ProteinModelPortal	Q9A8J8.
SMR	Q9A8J8. Positions 2-395.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	940801.
GenomeReviews	Gene locus CC_1355 in contig AE005673_GR.
KEGG	ccr:CC_1355.
NMPDR	fig|190650.1.peg.1348.
PATRIC	21299724. VBICauCre124313_1384.
TIGR	CC_1355.
Phylogenomic databases
HOGENOM	HBG649839.
OMA	HLKESNE.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9A8J8_CAUCR

Accession

Primary (citable) accession number: Q9A8J8

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)