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Protein

Sulfate adenylyltransferase subunit 2

Gene

cysD

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + sulfate = diphosphate + adenylyl sulfate.UniRule annotation

Pathwayi: hydrogen sulfide biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Sulfate adenylyltransferase subunit 2 (cysD)
  2. no protein annotated in this organism
  3. Phosphoadenylyl-sulfate reductase (thioredoxin) (CC_1121)
This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAULO:CC1483-MONOMER.
UniPathwayiUPA00140; UER00204.

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate adenylyltransferase subunit 2UniRule annotation (EC:2.7.7.4UniRule annotation)
Alternative name(s):
ATP-sulfurylase small subunitUniRule annotation
Sulfate adenylate transferaseUniRule annotation
Short name:
SATUniRule annotation
Gene namesi
Name:cysDUniRule annotation
Ordered Locus Names:CC_1483
OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001816 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Sulfate adenylyltransferase subunit 2PRO_0000340190Add
BLAST

Interactioni

Subunit structurei

Heterodimer composed of CysD, the smaller subunit, and CysN.UniRule annotation

Protein-protein interaction databases

STRINGi190650.CC_1483.

Structurei

3D structure databases

ProteinModelPortaliQ9A881.
SMRiQ9A881. Positions 14-221.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PAPS reductase family. CysD subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C11. Bacteria.
COG0175. LUCA.
HOGENOMiHOG000263604.
KOiK00957.
OMAiQSASMEK.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00064. Sulf_adenylyltr_sub2. 1 hit.
InterProiIPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
IPR011784. SO4_adenylTrfase_ssu.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMsiTIGR02039. CysD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9A881-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPDLTQSAI TPARLTHLQR LEAESIHILR EVAAECERPV MLYSIGKDSA
60 70 80 90 100
VMLHLAAKAF YPSKPPFPLL HIDTTWKFRD MYALRDRIGS EMGFDLLVHK
110 120 130 140 150
NPDAQARGIN PFDHGSAVHT DLWKTEGLKQ ALSKYGFDAA FGGARRDEEK
160 170 180 190 200
SRAKERVFSF RSSEHRWDPK NQRPELWNLY NTRKHPGESL RVFPISNWTE
210 220 230 240 250
LDIWQYIHLE NIPIVPLYFA AERPVVERDG ALIMVDDDRF RLRDGEVPQM
260 270 280 290 300
RSVRFRTLGC YPLTGAVEST AATLPQVIQE MLLATTSERQ GRVIDHDQSA
310
SMEKKKQEGY F
Length:311
Mass (Da):35,751
Last modified:June 1, 2001 - v1
Checksum:iEEF93D8E39BB209B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23462.1.
PIRiB87433.
RefSeqiNP_420294.1. NC_002696.2.
WP_010919357.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK23462; AAK23462; CC_1483.
GeneIDi941837.
KEGGiccr:CC_1483.
PATRICi21299986. VBICauCre124313_1510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23462.1.
PIRiB87433.
RefSeqiNP_420294.1. NC_002696.2.
WP_010919357.1. NC_002696.2.

3D structure databases

ProteinModelPortaliQ9A881.
SMRiQ9A881. Positions 14-221.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190650.CC_1483.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK23462; AAK23462; CC_1483.
GeneIDi941837.
KEGGiccr:CC_1483.
PATRICi21299986. VBICauCre124313_1510.

Phylogenomic databases

eggNOGiENOG4105C11. Bacteria.
COG0175. LUCA.
HOGENOMiHOG000263604.
KOiK00957.
OMAiQSASMEK.

Enzyme and pathway databases

UniPathwayiUPA00140; UER00204.
BioCyciCAULO:CC1483-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00064. Sulf_adenylyltr_sub2. 1 hit.
InterProiIPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
IPR011784. SO4_adenylTrfase_ssu.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMsiTIGR02039. CysD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYSD_CAUCR
AccessioniPrimary (citable) accession number: Q9A881
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.