Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uronate isomerase

Gene

uxaC

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciCAULO:CC1490-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:CC_1490
OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001816 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727661 – 487Uronate isomeraseAdd BLAST487

Interactioni

Protein-protein interaction databases

STRINGi190650.CC_1490.

Structurei

Secondary structure

1487
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni9 – 12Combined sources4
Helixi17 – 28Combined sources12
Turni29 – 32Combined sources4
Beta strandi35 – 37Combined sources3
Helixi45 – 49Combined sources5
Helixi56 – 59Combined sources4
Helixi65 – 72Combined sources8
Turni73 – 75Combined sources3
Turni79 – 82Combined sources4
Helixi94 – 103Combined sources10
Helixi105 – 108Combined sources4
Helixi112 – 123Combined sources12
Turni133 – 135Combined sources3
Helixi136 – 147Combined sources12
Helixi150 – 152Combined sources3
Helixi154 – 160Combined sources7
Beta strandi163 – 167Combined sources5
Helixi177 – 184Combined sources8
Turni199 – 201Combined sources3
Helixi208 – 219Combined sources12
Helixi226 – 242Combined sources17
Beta strandi247 – 250Combined sources4
Helixi262 – 274Combined sources13
Helixi279 – 300Combined sources22
Beta strandi303 – 306Combined sources4
Helixi316 – 321Combined sources6
Beta strandi324 – 327Combined sources4
Turni337 – 339Combined sources3
Helixi341 – 347Combined sources7
Beta strandi355 – 357Combined sources3
Helixi364 – 367Combined sources4
Helixi369 – 373Combined sources5
Beta strandi379 – 381Combined sources3
Helixi386 – 388Combined sources3
Helixi391 – 405Combined sources15
Helixi420 – 422Combined sources3
Helixi423 – 443Combined sources21
Helixi449 – 460Combined sources12
Helixi462 – 467Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Q01X-ray2.34A/B/C2-487[»]
ProteinModelPortaliQ9A874.
SMRiQ9A874.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9A874.

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9A874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARPLSFHED RLFPSDPATR SYARGLYALV KDLPIISPHG HTDPSWFATN
60 70 80 90 100
APFQDATDLL LAPDHYLFRM LYSQGVSLDA LKVRSKAGVP DTDPREAWRV
110 120 130 140 150
FASHFYLFRG TPSWVWLNHV FSQVFGFTEF LEASNADDYF DRITAALATD
160 170 180 190 200
AFRPRALFDR FNIETLATTE GPHESLQHHA AIRESGWGGH VITAYRPDAV
210 220 230 240 250
IDFEDERSPR AFERFAETSG QDVYSWKSYL EAHRLRRQAF IDAGATSSDH
260 270 280 290 300
GHPTAATADL SDVEAEALFN SLVKGDVTPE KAELFRAQML TEMAKMSLDD
310 320 330 340 350
GLVMQIHPGS HRNHNVGLLN SHGRDKGADI PMRTEYVDAL KPLLTRLGND
360 370 380 390 400
PRLSIILFTL DETTYSRELA PLAGHYPVLK LGPSWWFHDS PEGMMRFREQ
410 420 430 440 450
VTETAGFYNT VGFNDDTRAF LSIPARHDVA RRVDSAFLAR MVAEHRMDLV
460 470 480
EAEELIVDLT YNLPKKAYKL DQRPDWARPA TLRAAAE
Length:487
Mass (Da):55,052
Last modified:June 1, 2001 - v1
Checksum:i0FA4C80E085ED4F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23469.1.
PIRiA87434.
RefSeqiNP_420301.1. NC_002696.2.
WP_010919364.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK23469; AAK23469; CC_1490.
GeneIDi941836.
KEGGiccr:CC_1490.
PATRICi21300000. VBICauCre124313_1517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23469.1.
PIRiA87434.
RefSeqiNP_420301.1. NC_002696.2.
WP_010919364.1. NC_002696.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Q01X-ray2.34A/B/C2-487[»]
ProteinModelPortaliQ9A874.
SMRiQ9A874.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190650.CC_1490.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK23469; AAK23469; CC_1490.
GeneIDi941836.
KEGGiccr:CC_1490.
PATRICi21300000. VBICauCre124313_1517.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciCAULO:CC1490-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9A874.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_CAUCR
AccessioniPrimary (citable) accession number: Q9A874
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.