Q9A873 (KDUI_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
EC=5.3.1.17

Alternative name(s):
5-keto-4-deoxyuronate isomerase
DKI isomerase

Gene names

Name:	kduI
Ordered Locus Names:	CC_1491

Organism

Caulobacter crescentus (Caulobacter vibrioides)

Taxonomic identifier

155892 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. HAMAP MF_00687
Pathway	Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 4/5. HAMAP MF_00687
Sequence similarities	Belongs to the kduI family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pectin catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 279	279	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase HAMAP MF_00687		PRO_0000215484

Sequences

	Sequence		Length	Mass (Da)
	Q9A873 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: BB1511A1959DF187	FASTA	279	31,050
	10 20 30 40 50 60 MFAKTYHATH PDMMFAVSND DLRDRYLMQG LFQDGQIVLT YNHAERFVVG GVVATSPIKL 70 80 90 100 110 120 PDQTEPASAA GHPFLERREL GVINVGDTTG KITVDGVAYE IVPRDGLYVT MGAKDVTFEG 130 140 150 160 170 180 VDGAARFYLV SLPAHAAFET KKLAFADAIP LERGALETSN ERTIYQYIVP TTCKSAQLLL 190 200 210 220 230 240 GMTVLKPGSV WNTMPPHLHD RRSEAYFYFG LGENDRVFHY MGEPDEMRHI VIANEEAVMS 250 260 270 PPWSIHMGSG TANYTFIWAM GGENLDYTDM NVLDICQLK

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed: 11259647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005673 Genomic DNA. Translation: AAK23470.1.
PIR	B87434.
RefSeq	NP_420302.1. NC_002696.2.
3D structure databases
ProteinModelPortal	Q9A873.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	941207.
GenomeReviews	Gene locus CC_1491 in contig AE005673_GR.
KEGG	ccr:CC_1491.
NMPDR	fig|190650.1.peg.1482.
PATRIC	21300002. VBICauCre124313_1518.
TIGR	CC_1491.
Phylogenomic databases
HOGENOM	HBG301328.
OMA	AKFYLVS.
ProtClustDB	PRK00924.
Family and domain databases
HAMAP	MF_00687. KduI. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR007045. KduI. IPR021120. KduI/IolB_isomerase. [Graphical view]
KO	K01815.
Pfam	PF04962. KduI. 1 hit. [Graphical view]
PIRSF	PIRSF006625. KduI. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KDUI_CAUCR

Accession

Primary (citable) accession number: Q9A873

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program