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Q9A805 (RNC_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:CC_1560
OrganismCaulobacter crescentus (strain ATCC 19089 / CB15) [Reference proteome] [HAMAP]
Taxonomic identifier190650 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 231231Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000180384

Regions

Domain8 – 135128RNase III
Domain161 – 23070DRBM

Sites

Active site521 Potential
Active site1241 By similarity
Metal binding481Magnesium By similarity
Metal binding1241Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9A805 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: B53F777CE9364C7B

FASTA23124,971
        10         20         30         40         50         60 
MDRRVAAVGD LERRIGHRFE DRELLERALT HASVGDGAKK VRDNEVLEFI GDRVLGLLAA 

        70         80         90        100        110        120 
EALAQRFPKA KEGELAPRLN ALVSRETCAR VARKAELGPA LRLSASSSKI GGRETDSILA 

       130        140        150        160        170        180 
GATEALMAAL YQDGGLEAAR KVFLDLWNDE FDRAGEGRPR DPKTALQEWA QGQGRPLPTY 

       190        200        210        220        230 
RVLDRTGPDH APVFTVEVSV TGVDPAIAKG KSRQEAEKAA AKALLEREGA G 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005673 Genomic DNA. Translation: AAK23539.1.
PIRG87442.
RefSeqNP_420371.1. NC_002696.2.

3D structure databases

ProteinModelPortalQ9A805.
SMRQ9A805. Positions 8-227.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK23539; AAK23539; CC_1560.
GeneID942457.
KEGGccr:CC_1560.
PATRIC21300144. VBICauCre124313_1589.

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246809.
KOK03685.
OMALTHKSCK.
OrthoDBEOG6T1WVS.
ProtClustDBCLSK890476.

Enzyme and pathway databases

BioCycCAULO:CC1560-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_CAUCR
AccessionPrimary (citable) accession number: Q9A805
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families