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Protein

Guanylate kinase

Gene

gmk

Organism
Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.By similarity

Catalytic activityi

ATP + GMP = ADP + GDP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi17 – 24ATPBy similarity8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAULO:CC1681-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
Name:gmk
Ordered Locus Names:CC_1681
OrganismiCaulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001816 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705171 – 213Guanylate kinaseAdd BLAST213

Interactioni

Protein-protein interaction databases

STRINGi190650.CC_1681.

Structurei

3D structure databases

ProteinModelPortaliQ9A7N9.
SMRiQ9A7N9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 189Guanylate kinase-likeAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.Curated

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037638.
KOiK00942.
OMAiAGNYYGT.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9A7N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSHHPHRG LLLMVVAPSG VGKTSLTRRL VSDHGDLHLS ISATTRDPRP
60 70 80 90 100
GEHDGRDYHF VSRDKFQGML AEDAFLEWAE VYGNFYGSPK APIMDALSRG
110 120 130 140 150
ESVLFDIDFQ GAMKVHKQAG ADSVLVYILP PSLAEMSRRL HTRSQDSEEV
160 170 180 190 200
IHRRLSRAKD EVAAWEQFDY VILNDDFDRA YADLAHIYHA ERLKRARNPW
210
IGDLVSDLLK EEI
Length:213
Mass (Da):24,219
Last modified:June 1, 2001 - v1
Checksum:iCA9796C7739EF056
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23659.1.
PIRiG87457.
RefSeqiNP_420491.1. NC_002696.2.
WP_010919552.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK23659; AAK23659; CC_1681.
GeneIDi942041.
KEGGiccr:CC_1681.
PATRICifig|190650.5.peg.1710.

Similar proteinsi

Entry informationi

Entry nameiKGUA_CAUVC
AccessioniPrimary (citable) accession number: Q9A7N9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome