ID   CALB_CAUCR              Reviewed;         485 AA.
AC   Q9A777;
DT   11-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   16-JUN-2009, entry version 46.
DE   RecName: Full=Probable coniferyl aldehyde dehydrogenase;
DE            Short=CALDH;
DE            EC=1.2.1.68;
GN   Name=calB; OrderedLocusNames=CC_1849;
OS   Caulobacter crescentus (Caulobacter vibrioides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=155892;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   MEDLINE=21173698; PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H.,
RA   Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J.,
RA   Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J.,
RA   Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L.,
RA   Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- CATALYTIC ACTIVITY: Coniferyl aldehyde + H(2)O + NAD(P)(+) =
CC       ferulate + NAD(P)H.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE005673; AAK23824.1; -; Genomic_DNA.
DR   PIR; D87478; D87478.
DR   RefSeq; NP_420656.1; -.
DR   HSSP; P11883; 1AD3.
DR   GeneID; 942308; -.
DR   GenomeReviews; AE005673_GR; CC_1849.
DR   KEGG; ccr:CC_1849; -.
DR   NMPDR; fig|190650.1.peg.1836; -.
DR   TIGR; CC_1849; -.
DR   HOGENOM; Q9A777; -.
DR   OMA; Q9A777; HPPYGTF.
DR   BRENDA; 1.2.1.68; 2191.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
DR   GO; GO:0050269; F:coniferyl-aldehyde dehydrogenase activity; IEA:EC.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR016160; Ald_DH_CS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   PANTHER; PTHR11699:SF15; ALDH; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    485       Probable coniferyl aldehyde
FT                                dehydrogenase.
FT                                /FTId=PRO_0000056586.
FT   ACT_SITE    226    226       By similarity.
FT   ACT_SITE    260    260       By similarity.
SQ   SEQUENCE   485 AA;  52721 MW;  8222ABB2DC5E78C1 CRC64;
     MNAPVNLSSD AHKAVMNDVL QRQKAAHLRD GPPSAEKRIQ WLNRCIDLLV GHQAEIAKAV
     NQDFGSRSPE ATSLTDVAGS IGPLKHAREH LTKWMKPEKH KTTPAILGLF GAKATVQWQP
     KGVVGVISPW NFPVNLTFAP LAGVFAAGNR AMIKPSEFTP ATSDLLKAMF AKAFNEEEVA
     VFVGGPEVGQ AFSGLAFDHL VFTGATSVAK HVMRAAAENL VPVTLELGGK SPVILSRGAD
     MATAAARVMN GKTLNAGQIC LAPDYVLAPQ EDVEAFVKEA QAAVSRYFPT IKDNPDYTAV
     VAQRHYDRVK GYVDDARAKG ARVIEINPAG EDLSQQEHRK IPPTLILDPT DDMKVMQEEI
     FGPVLPVKGY KTVDEAVDYV NAHDRPLALY WFGTDEAEKD RVLERTTSGG VTVNDVIFHV
     AQENLPFGGI GPAGMGAYHG YDGFREFSHR KAVFQQLKKD IAPMLGLRPP YGEGIRKYLA
     GQIKK
//